Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help.
Good luck - don't give up!! Sandt W > On June 7, 2019 at 9:55 PM Patricia Oliveira <[email protected]> wrote: > > Nori did not want to eat by herself so they are syringing food. They > started another medication for nausea, although she does not vomit, they > think that may be why she does not eat. > > Blood work showed changes in neutrophils (bizarre core?), veternary says > it can be from leukemia. > > The result of this transfusion was not as good as the other time :( > > i´ll talk to veterinary tomorrow morning again. > > thank you! > > Patrícia > > > > Em sex, 7 de jun de 2019 às 16:13, Amani Oakley < [email protected] > mailto:[email protected] > escreveu: > > > > > > Still sounds more like a transfusion reaction than anything with > > the meds. > > > > > > > > Hang in there. See what the afternoon labs show. > > > > > > > > Amani > > > > > > > > From: Felvtalk <[email protected] > > mailto:[email protected] > On Behalf Of Patricia Oliveira > > Sent: June 7, 2019 1:44 PM > > To: [email protected] mailto:[email protected] > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > Hi, Amani > > > > > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > > > > > I know it can be a reaction but i thought higher dose of > > prednisolone would prevent hemolysis. > > > > > > > > I also know it's normal for part of the red blood cells to be > > cleared right after the transfusion, but i don´t remember if it was icteric > > plasma on last one. > > > > > > > > I was hopefull she would come back home tomorrow, now i don´t know > > if it will be possible. > > > > > > > > Today she must have am echocardiogram too because x-ray showed an > > enlarged heart. > > > > > > > > Thank you! > > > > > > > > > > > > > > > > Em sex, 7 de jun de 2019 às 14:18, Amani Oakley > > <[email protected] mailto:[email protected] > escreveu: > > > > > > > > > > Hi Patricia > > > > > > > > > > > > The Stanozolol often has a side-effect of elevating liver > > > enzymes, though I cannot remember if it also increased bilirubin (which > > > would be what would cause the icteric observation of the plasma). > > > However, hang in there. If it is the Stanozolol, my experience is that > > > the liver enzymes drop right back to normal, shortly after it is > > > discontinued, and there is no lasting damage to the liver. For now, what > > > you have described (low temp and slightly lower heart rate) seems more > > > likely to be related to the transfusion itself, rather than anything else > > > going on. > > > > > > > > > > > > It is also possible that with the additional transfusion, > > > there is a higher than normal red cell destruction going on, which would > > > be another explanation for the increased icterus in the blood (which will > > > also show as an increase in bilirubin). Elevated bilirubin can often be > > > caused by a reaction to a blood transfusion. If the high bilirubin is the > > > indirect or the unconjugated portion, it is related to red cell break > > > down. The direct bilirubin (conjugated portion) is related to liver > > > function. The lab results are usually broken down to Total bilirubin and > > > Direct bilirubin. The indirect portion is obtained by subtracting the > > > direct amount from the total amount. > > > > > > > > > > > > I myself went through the pressure of the vets wanting me to > > > discontinue the Stanozolol because of abnormal liver enzymes. My logic > > > was that there was nothing else. If I discontinued the Stanozolol, my cat > > > would die, period. I continued and found that in the end, the liver > > > enzymes normalized on their own, even though I had Zander on almost > > > continuous Stanozolol for close to two years. > > > > > > > > > > > > I know that you know that you are only temporarily helping > > > Nori with blood transfusions, and the virus is still attacking cells, > > > etc. In my opinion – and mine alone – my experience and research leads me > > > to the conclusion that the combination of > > > Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell > > > production, but I believe that the Doxycyline assisted in keeping the > > > viruses from properly reproducing. > > > > > > > > > > > > However, anticipate that when the vet gets back the second > > > set of blood work, she may well try to tell you to discontinue the > > > Stanozolol. > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk <[email protected] > > > mailto:[email protected] > On Behalf Of Patricia > > > Oliveira > > > Sent: June 7, 2019 12:53 PM > > > To: [email protected] > > > mailto:[email protected] > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > Nori got another transfusion last night, hematocrit was 11.9 > > > before it. > > > > > > > > > > > > Today morning, i talk to the hospital's veterinarian, she > > > said hematocrit went to 29 and Nori was fine, all normal parameters and > > > eating by herself again. > > > > > > > > > > > > But plasma was intensely icteric. I think this means red > > > cells being destroyed, isn't it? > > > > > > > > > > > > About one hour ago, veterinarian said Nori was with low > > > temperature and heart rate slightly lower than normal. She was waiting > > > the new blood work. In the morning, it was done only hematocrit, not > > > complete blood work. > > > > > > > > > > > > i am worried again. > > > > > > > > > > > > Thank you, > > > > > > > > > > > > Patrícia > > > > > > > > > > > > Em ter, 4 de jun de 2019 às 23:46, Amani Oakley > > > <[email protected] mailto:[email protected] > escreveu: > > > > > > > > > > > > > > I would be leery of the going the route suggested by > > > > the vet at this juncture. I seriously seriously doubt if the > > > > erythropoietin will help. See my earlier where I explain why. > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > From: Felvtalk <[email protected] > > > > mailto:[email protected] > On Behalf Of Patricia > > > > Oliveira > > > > Sent: June 4, 2019 8:53 PM > > > > To: [email protected] > > > > mailto:[email protected] > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > Hi, Lorraine > > > > > > > > > > > > > > > > Veterinary wants to increase prednisolone to > > > > immunosuppressive dose and add erythropoietin. She thinks it is > > > > immune-mediated anemia and not mycoplasma. > > > > > > > > > > > > > > > > Nori is receiving 1,2 mg prednisolone, twice a day. > > > > She weighs only 1 kg. > > > > > > > > > > > > > > > > We did x-ray today too. No visible tumor but we found a > > > > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > > > > > > > > > > > > > :( > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em ter, 4 de jun de 2019 às 20:50, Lorraine Johnston > > > > <[email protected] mailto:[email protected] > escreveu: > > > > > > > > > > > > > > > > > > Patricia, > > > > > > > > > > > > > > > > > > > > I would go with the transfusion and also start > > > > > erythropoietin. Stanozolol is supposed to stimulate erythropoietin > > > > > production, but she might need a boost of the ready-made drug just to > > > > > keep her alive until then. > > > > > > > > > > > > > > > > > > > > - Lorraine > > > > > > > > > > > > > > > > > > > > "Sometimes it is the people no one can imagine > > > > > anything of who do the things no one can imagine." - Alan Turing > > > > > > > > > > > > > > > > > > > > From: Felvtalk > > > > > [mailto:[email protected] > > > > > mailto:[email protected] ] On Behalf Of Patricia > > > > > Oliveira > > > > > Sent: Tuesday, June 4, 2019 6:34 PM > > > > > To: [email protected] > > > > > mailto:[email protected] > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > Hi, > > > > > > > > > > > > > > > > > > > > We did another blood work today, her hematocrit > > > > > is 13% now :( > > > > > > > > > > > > > > > > > > > > She is very sleepy but responsive when i talk to > > > > > her. > > > > > > > > > > > > > > > > > > > > I don´t know if i can wait some more days to see > > > > > if stanozolol is working. Or maybe it would be better get another > > > > > transfusion right now. > > > > > > > > > > > > > > > > > > > > Today, vet talk about erythropoietin. Do you know > > > > > if it can be used with stanozolol? > > > > > > > > > > > > > > > > > > > > Thank you, > > > > > > > > > > > > > > > > > > > > Patrícia > > > > > > > > > > > > > > > > > > > > Em sáb, 1 de jun de 2019 às 14:44, Amani Oakley > > > > > <[email protected] mailto:[email protected] > escreveu: > > > > > > > > > > > > > > > > > > > > > > Hi Patricia – I gave all the pills > > > > > > together, morning and evening, except for the metoclopramide which > > > > > > was given ½ or so before meals. The rest I gave with the meals. I > > > > > > didn’t observe a problem with giving them together. > > > > > > > > > > > > > > > > > > > > > > > > You might also try baby food to get Nori to > > > > > > eat. Get the pureed kind (beef or chicken with or without > > > > > > vegetables), so it can be sucked up into a syringe. If my Zander > > > > > > wasn’t eating (and he wasn’t at the start of the medication > > > > > > regime), then I would use a syringe to get the baby food into him. > > > > > > Baby food is easy to digest and has good things in it. I would > > > > > > target – say – five 3 cc syringe-fulls at each feeding. I would > > > > > > boost the number of syringe-fulls if possible. Eventually, Zander > > > > > > started eating the baby food on his own, and then I graduated to > > > > > > moist food, and really, anything he wanted until he put the weight > > > > > > back on. > > > > > > > > > > > > > > > > > > > > > > > > I had a look at the picture you sent and > > > > > > Nori is adorable. I am crossing my fingers for you and for Nori. > > > > > > Keep us updated on her progress. > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk > > > > > > <[email protected] > > > > > > mailto:[email protected] > On Behalf Of Patricia > > > > > > Oliveira > > > > > > Sent: June 1, 2019 12:36 PM > > > > > > To: [email protected] > > > > > > mailto:[email protected] > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv > > > > > > + > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > > > > > > > > > > > > > Thanky you very much for you email! > > > > > > > > > > > > > > > > > > > > > > > > Nori was discharged from the hospital > > > > > > yesterday night. She is eating baby dry food. I tried canned but > > > > > > she didn´t accept so weel. > > > > > > > > > > > > > > > > > > > > > > > > Today i bought other kinds of canned, i'll > > > > > > try them hoping she likes some one. > > > > > > > > > > > > > > > > > > > > > > > > Compound pharmacy must delivery stanozolol > > > > > > today. > > > > > > > > > > > > > > > > > > > > > > > > Are there any precautions regarding > > > > > > medication schedules? Close or far to doxy, for example? > > > > > > > > > > > > > > > > > > > > > > > > This is Nori: > > > > > > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > Patrícia > > > > > > > > > > > > > > > > > > > > > > > > Em qui, 30 de mai de 2019 às 20:52, Amani > > > > > > Oakley <[email protected] mailto:[email protected] > > > > > > > escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > Sorry Patricia – after going on and > > > > > > > on in my last email, I realized I hadn’t actually answered your > > > > > > > question. I think you can probably use the stanozolol with the > > > > > > > Doxycycline, without the prednisone, but prednisone itself has > > > > > > > properties which help to boost red cell production. Try it out, > > > > > > > keep close tabs on the haematology results and see if you are > > > > > > > getting a good response on just Doxycycline and the Stanozolol. > > > > > > > If not, add the prednisone. You may find that this combination > > > > > > > assists with the FIP as well, as per my previous email. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk > > > > > > > <[email protected] > > > > > > > mailto:[email protected] > On Behalf Of > > > > > > > Patricia Oliveira > > > > > > > Sent: May 30, 2019 12:56 PM > > > > > > > To: [email protected] > > > > > > > mailto:[email protected] > > > > > > > Subject: [Felvtalk] Rescued kitten > > > > > > > felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi from Brazil, > > > > > > > > > > > > > > > > > > > > > > > > > > > > I rescued a very weak, dehydrated, > > > > > > > extremely thin kitten. > > > > > > > > > > > > > > > > > > > > > She's hospitalized now. Her > > > > > > > hematocrit was 8, had blood transfusion which raised hematocrit > > > > > > > to 22, now it is 19. Low reticulocyte count. > > > > > > > > > > > > > > She has difficulty walking, which we > > > > > > > can not define if it is just weakness or neurological. Already > > > > > > > had a seizure. > > > > > > > > > > > > > > She also have changes in her kidneys. > > > > > > > It has been tested and is felv + > > > > > > > > > > > > > > She is receiving doxy and the > > > > > > > hospital vets would like to include prednisolone. > > > > > > > > > > > > > > However, as it is not possible yet to > > > > > > > rule out PIF, and the medication I could use in the case of PIF > > > > > > > does not work if the cat received prednisolone, I am trying to > > > > > > > avoid it. > > > > > > > > > > > > > > The veterinarian agreed to prescribe > > > > > > > stanozolol. > > > > > > > > > > > > > > Can it be used without prednisolone, > > > > > > > only with doxy she is already receiving? > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patrícia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > _______________________________________________ > Felvtalk mailing list > [email protected] > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >
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