Thank you for clarification.. I think I understand now. I guess my question is do FELV+ cats develop all strains? Or do some get A and then either B or C?
Chris [EMAIL PROTECTED] -----Original Message----- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Ong Meo Sent: Wednesday, December 08, 2004 12:50 PM To: [EMAIL PROTECTED] Subject: Re: contagiousness of FELV and other thoughts.../strain ----- Original Message ----- From: "Chris" <[EMAIL PROTECTED]> To: <[EMAIL PROTECTED]> Sent: Wednesday, December 08, 2004 12:35 PM Subject: RE: contagiousness of FELV and other thoughts.../strain > OK-- so what you're saying is that depending on the strain of FELV, it is > NOT contagious? No, I don't think that's what I said. I believe I said "FeLV-A occurs in all FeLV-infected cats and causes severe immunosuppression" "Only FeLV-A is transmitted contagiously among cats." "FeLV-B or -C are generated de novo by recombination between endogenous FeLV sequences and the infecting FeLV-A. FeLV-B and FeLV-C are not transmitted contagiously among cats in nature." IOW, all FeLV infected cats are infected with FeLV-A which is tramsmitted contagiously among cats. FeLV-B and C are generated within the cat by recombination with the infecting FeLV-A and endogenous FeLV sequences. I hope this clears up your confusion. Ong If so, then it really puts into question the tests > routinely used? What tests could be used to determine the strain? > > Chris > [EMAIL PROTECTED] > > -----Original Message----- > From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf > Of Ong Meo > Sent: Wednesday, December 08, 2004 12:26 PM > To: [EMAIL PROTECTED] > Subject: Re: contagiousness of FELV and other thoughts.../strain > > > ----- Original Message ----- > From: "Gloria B. Lane" <[EMAIL PROTECTED]> > To: <[EMAIL PROTECTED]> > Sent: Wednesday, December 08, 2004 9:03 AM > Subject: Re: contagiousness of FELV and other thoughts.../strain > > > > I appreciate the thoughtfulness of what you've written so much. I've > > mixed FELV with negatives, no prob. But always a question - shudder. > > > > Have wondered for some time about strains. Does anybody know if > > there's an available test for the strain of FELV? > > > > Gloria > > > Hi Gloria, > > I'm new to the group; I hope you don't mind if I butt in. > > The differences in the outcome of FeLV infection can be attributed to > differences in virus subgroups that may be considered strains. FeLV-A, > FeLV-B, and FeLV-C. > Only FeLV-A is transmitted contagiously among cats. FeLV-B or -C are > generated de novo by recombination between endogenous FeLV sequences and the > infecting FeLV-A. FeLV-B and FeLV-C are not transmitted contagiously among > cats in nature. The subgroups are determined by viral interference assays. > These are highly specialized tests and usually available only in research > and specialized diagnostic labs. > > FeLV-A occurs in all FeLV-infected cats and causes severe immunosuppression > (weakened immune system). > > FeLV-B occurs in about 50% of all FeLV-infected cats and causes more > neoplastic disease (i.e., tumors and other abnormal tissue growths) than > cats infected only with FeLV-A. > > FeLV-C occurs in about 1% of FeLV-infected cats and causes severe anemia. > > hth, > > Ong > > > > > >
