----- Original Message ----- From: "Tad Burnett" <[EMAIL PROTECTED]> To: <[EMAIL PROTECTED]> Sent: Wednesday, December 08, 2004 1:34 PM Subject: Re: contagiousness of FELV and other thoughts.../strain
> I think I have heard of the A, B and C as stages rather than strain... Subgroups are not the same as stages. There are 6 stages of FeLV infection. Early Infection (Phases I to 3) Hemolymphatic and Intestinal Infection (Phase 4) Phase 4 is the pivotal phase. If the total virus burden exceeds the cat's anti-FeLV immune responses, the cat will develop persistent viremia. If the cat's immune response is successful in limiting or eliminating FeLV, the cat will develop either latent, extinguished, or sequestered FeLV infection. Marrow-Origin Viremia (Phase 5) Widespread Replication of FeLV (Phase 6) Ong > I have also heard that their are 8 differant strains of the virous...I > would think that would be a part of stage A.....Pretty sure it is > posible to identify what stage the cat is in...but I don't know if there > is anyway to identify what strain an A+ cat has.... FeLV-A is a *subgroup*. All FeLV positive cats are infected with FELV-A. Subgroups are determined by viral interference assays. > Tad (I don't know what I am talking about but just my guess) > > Ong Meo wrote: > > >----- Original Message ----- > >From: "Chris" <[EMAIL PROTECTED]> > >To: <[EMAIL PROTECTED]> > >Sent: Wednesday, December 08, 2004 12:56 PM > >Subject: RE: contagiousness of FELV and other thoughts.../strain > > > > > > > > > >>Thank you for clarification.. > >> > >> > > > >No no. It was my fault for not being clearer. I tend to ramble on since > >this disease is always on my mind. > > > > > > I think I understand now. I guess my question > > > > > >>is do FELV+ cats develop all strains? > >> > >> > > > >Not necessarily. > > > > > >Or do some get A and then either B or > > > > > >>C? > >> > >> > > > >All FeLV-infected cats are infected with FeLV-A. About 50% of the > >FeLV-infected cats generate FeLV-B, and only about 1% generate FeLV-C. > > > >A cat cannot have FeLV-B, or C without having FeLV-A. > > > >Ong. > > > > > > > > > >>Chris > >>[EMAIL PROTECTED] > >> > >>-----Original Message----- > >>From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On > >> > >> > >Behalf > > > > > >>Of Ong Meo > >>Sent: Wednesday, December 08, 2004 12:50 PM > >>To: [EMAIL PROTECTED] > >>Subject: Re: contagiousness of FELV and other thoughts.../strain > >> > >> > >>----- Original Message ----- > >>From: "Chris" <[EMAIL PROTECTED]> > >>To: <[EMAIL PROTECTED]> > >>Sent: Wednesday, December 08, 2004 12:35 PM > >>Subject: RE: contagiousness of FELV and other thoughts.../strain > >> > >> > >> > >> > >>>OK-- so what you're saying is that depending on the strain of FELV, it > >>> > >>> > >is > > > > > >>>NOT contagious? > >>> > >>> > >>No, I don't think that's what I said. I believe I said "FeLV-A occurs in > >>all FeLV-infected cats and causes severe immunosuppression" "Only FeLV-A > >> > >> > >is > > > > > >>transmitted contagiously among cats." > >> > >>"FeLV-B or -C are generated de novo by recombination between endogenous > >> > >> > >FeLV > > > > > >>sequences and the infecting FeLV-A. FeLV-B and FeLV-C are not transmitted > >>contagiously among cats in nature." > >> > >>IOW, all FeLV infected cats are infected with FeLV-A which is tramsmitted > >>contagiously among cats. FeLV-B and C are generated within the cat by > >>recombination with the infecting FeLV-A and endogenous FeLV sequences. > >> > >>I hope this clears up your confusion. > >> > >>Ong > >> > >> > >> > >>If so, then it really puts into question the tests > >> > >> > >>>routinely used? What tests could be used to determine the strain? > >>> > >>>Chris > >>>[EMAIL PROTECTED] > >>> > >>>-----Original Message----- > >>>From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On > >>> > >>> > >>Behalf > >> > >> > >>>Of Ong Meo > >>>Sent: Wednesday, December 08, 2004 12:26 PM > >>>To: [EMAIL PROTECTED] > >>>Subject: Re: contagiousness of FELV and other thoughts.../strain > >>> > >>> > >>>----- Original Message ----- > >>>From: "Gloria B. Lane" <[EMAIL PROTECTED]> > >>>To: <[EMAIL PROTECTED]> > >>>Sent: Wednesday, December 08, 2004 9:03 AM > >>>Subject: Re: contagiousness of FELV and other thoughts.../strain > >>> > >>> > >>> > >>> > >>>>I appreciate the thoughtfulness of what you've written so much. I've > >>>>mixed FELV with negatives, no prob. But always a question - shudder. > >>>> > >>>>Have wondered for some time about strains. Does anybody know if > >>>>there's an available test for the strain of FELV? > >>>> > >>>>Gloria > >>>> > >>>> > >>>Hi Gloria, > >>> > >>>I'm new to the group; I hope you don't mind if I butt in. > >>> > >>>The differences in the outcome of FeLV infection can be attributed to > >>>differences in virus subgroups that may be considered strains. FeLV-A, > >>>FeLV-B, and FeLV-C. > >>>Only FeLV-A is transmitted contagiously among cats. FeLV-B or -C are > >>>generated de novo by recombination between endogenous FeLV sequences and > >>> > >>> > >>the > >> > >> > >>>infecting FeLV-A. FeLV-B and FeLV-C are not transmitted contagiously > >>> > >>> > >>among > >> > >> > >>>cats in nature. The subgroups are determined by viral interference > >>> > >>> > >>assays. > >> > >> > >>>These are highly specialized tests and usually available only in > >>> > >>> > >research > > > > > >>>and specialized diagnostic labs. > >>> > >>>FeLV-A occurs in all FeLV-infected cats and causes severe > >>> > >>> > >>immunosuppression > >> > >> > >>>(weakened immune system). > >>> > >>>FeLV-B occurs in about 50% of all FeLV-infected cats and causes more > >>>neoplastic disease (i.e., tumors and other abnormal tissue growths) than > >>>cats infected only with FeLV-A. > >>> > >>>FeLV-C occurs in about 1% of FeLV-infected cats and causes severe > >>> > >>> > >anemia. > > > > > >>>hth, > >>> > >>>Ong > >>> > >>> > >>> > >>> > >>> > >>> > >>> > >>> > >> > >> > >> > >> > > > > > > > > > > > > > ---------------------------------------------------------------------------- ---- No virus found in this outgoing message. Checked by AVG Anti-Virus. Version: 7.0.289 / Virus Database: 265.4.7 - Release Date: 12/7/2004
