----- Original Message ----- 
From: "Chris" <[EMAIL PROTECTED]>
To: <[EMAIL PROTECTED]>
Sent: Wednesday, December 08, 2004 12:56 PM
Subject: RE: contagiousness of FELV and other thoughts.../strain


> Thank you for clarification..

No no. It was my fault for not being clearer.  I tend to ramble on since
this disease is always on my mind.


 I think I understand now. I guess my question
> is do FELV+ cats develop all strains?

Not necessarily.


Or do some get A and then either B or
> C?

All FeLV-infected cats are infected with FeLV-A.  About 50% of the
FeLV-infected cats generate FeLV-B, and only about 1% generate FeLV-C.

A cat cannot have FeLV-B, or C without having FeLV-A.

Ong.


>
> Chris
> [EMAIL PROTECTED]
>
> -----Original Message-----
> From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On
Behalf
> Of Ong Meo
> Sent: Wednesday, December 08, 2004 12:50 PM
> To: [EMAIL PROTECTED]
> Subject: Re: contagiousness of FELV and other thoughts.../strain
>
>
> ----- Original Message ----- 
> From: "Chris" <[EMAIL PROTECTED]>
> To: <[EMAIL PROTECTED]>
> Sent: Wednesday, December 08, 2004 12:35 PM
> Subject: RE: contagiousness of FELV and other thoughts.../strain
>
>
> > OK-- so what you're saying is that depending on the strain of FELV, it
is
> > NOT contagious?
>
> No, I don't think that's what I said.  I believe I said "FeLV-A occurs in
> all FeLV-infected cats and causes severe immunosuppression"  "Only FeLV-A
is
> transmitted contagiously among cats."
>
> "FeLV-B or -C are generated de novo by recombination between endogenous
FeLV
> sequences and the infecting FeLV-A.  FeLV-B and FeLV-C are not transmitted
> contagiously among cats in nature."
>
> IOW, all FeLV infected cats are infected with FeLV-A which is tramsmitted
> contagiously among cats.  FeLV-B and C are generated within the cat by
> recombination with the infecting FeLV-A and endogenous FeLV sequences.
>
> I hope this clears up your confusion.
>
> Ong
>
>
>
> If so, then it really puts into question the tests
> > routinely used?  What tests could be used to determine the strain?
> >
> > Chris
> > [EMAIL PROTECTED]
> >
> > -----Original Message-----
> > From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On
> Behalf
> > Of Ong Meo
> > Sent: Wednesday, December 08, 2004 12:26 PM
> > To: [EMAIL PROTECTED]
> > Subject: Re: contagiousness of FELV and other thoughts.../strain
> >
> >
> > ----- Original Message ----- 
> > From: "Gloria B. Lane" <[EMAIL PROTECTED]>
> > To: <[EMAIL PROTECTED]>
> > Sent: Wednesday, December 08, 2004 9:03 AM
> > Subject: Re: contagiousness of FELV and other thoughts.../strain
> >
> >
> > > I appreciate the thoughtfulness of what you've written so much.  I've
> > > mixed FELV with negatives, no prob.  But always a question - shudder.
> > >
> > > Have wondered for some time about strains.  Does anybody know if
> > > there's an available test for the strain of FELV?
> > >
> > > Gloria
> >
> >
> > Hi Gloria,
> >
> > I'm new to the group; I hope you don't mind if I butt in.
> >
> > The differences in the outcome of FeLV infection can be attributed to
> > differences in virus subgroups that may be considered strains.  FeLV-A,
> > FeLV-B, and FeLV-C.
> > Only FeLV-A is transmitted contagiously among cats.  FeLV-B or -C are
> > generated de novo by recombination between endogenous FeLV sequences and
> the
> > infecting FeLV-A.  FeLV-B and FeLV-C are not transmitted contagiously
> among
> > cats in nature.  The subgroups are determined by viral interference
> assays.
> > These are highly specialized tests and usually available only in
research
> > and specialized diagnostic labs.
> >
> > FeLV-A occurs in all FeLV-infected cats and causes severe
> immunosuppression
> > (weakened immune system).
> >
> > FeLV-B occurs in about 50% of all FeLV-infected cats and causes more
> > neoplastic disease (i.e., tumors and other abnormal tissue growths) than
> > cats infected only with FeLV-A.
> >
> > FeLV-C occurs in about 1% of FeLV-infected cats and causes severe
anemia.
> >
> > hth,
> >
> > Ong
> >
> >
> >
> >
> >
> >
>
>
>
>


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