Introns are spaces between different coding sections of a gene (exons)... and 
are generally considered part of the gene...
or more precisely 5'UTR, Introns, Exons, and the 3'UTR make up a gene. These do 
not usually fall into the "junk DNA category"
http://www.accessexcellence.org/RC/VL/GG/rna_synth.html

In DNA there are also sections of DNA before and behind the gene that are used 
to regulate it (turn it on and off). This does fall into the Junk category. 
Around that there is more DNA that contains non-functional genes, places for 
scaffolding proteins to attach, places for histones to attach, and a ton of 
other stuff that we are unsure of what it's function is. This is also in the 
Junk category - tho IMO none of it is really junk.

There are a lot of "genetic" diseases like Type II diabetes, autism, and 
certian inheritable cancers that show patterns that are in the non-translated 
DNA (introns) or in the non-transcribed DNA (junk) that may be linked to the 
disease or may be a result of the disease, this becomes typical chicken and egg 
arguing - but it happens alot in science. I wasn't disputing your using it as 
hand waving science for an explination... as a matter of fact, if you want to 
model a very rare condition (like magery) it's probably the best way to do it. 
However, I'm anal enough to correct a mistake you made in your terminology 
(introns are part of your genes) and to try to get people and the media away 
from using the term "Junk DNA" - I term I abhor. I have worked on questions of 
gene regulation for a large part of my career, and I personally don't think I 
work on "Junk DNA", and I find the term misleads the public to what is really 
going on.

I definately think if you want to model Magery as a genetic condition working 
it as a mendalian inheritance (all the AA BB CC stuff) is not going to get you 
where you want. Modeling it after something like height, weight, or autism will 
probably give you the results you want.... It also means you can do a lot of 
hand waving and not describe the reasons behind the condition fully.
-Sue


----- Original Message ----
From: COYT WATTERS <[EMAIL PROTECTED]>
To: The GURPSnet mailing list <[email protected]>
Sent: Monday, April 30, 2007 6:41:25 AM
Subject: Re: [gurps] Fake scientific genetics for Magery...


I used the interviewer / interviewee's terms.  Honestly at the time I could not 
think of the spelling for intron (I keep wanting to inert another 'o' for some 
reason), and web access was problematic!

The long and the short of the interview was that they sequenced a number of 
patients with Type-II diabetes, and there were genetic and at least one 
intronic patterns which matched, the interviewee may have been simplifying or 
using the interviewer's terminology.

Since introns actual use isn't as clearly understood as genes, it's a 
convenient "hand waving science" for a "genetic" basis for anything, from 
Supers to Magery.




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