At 04:41 PM 4/30/2007 -0700, you wrote: >Yeah, I'd go for epigentic effect too... but you pretty much can't mathematically model that at all, what with the various combinations of protiens interaction and mi/siRNA effects you can have with that. Not to mention all the womb condition possibilities. > >But if Hal wants something that's a bit more mathematically calculable then I'd go for a non-standard inheritance pattern - like the alzheimer's or parkinson's where the condition gets more severe the more repeated motifs you have. That way he can have incomplete penetrance effects; or high break over conditions droping the number of mages in the population even if it is a benifical mutation; or pretty much any bizzare numbers and combinations he wants. >With that type of model he can even get combinations of two magery 3 parents that have only mundane childern if after a certian number of repeats the gene disfunctions entirely giving a mundane child who can only have mundane childern. >;) >Basically >0-10 repeats = normal functioning proteins >10-20 repeats = magery 1 high activity protiens >20-30 repeats = magery 2 super high activity proteins >30-35 repeats = magery 3 mega high activity proteins >35+ repeats = gene is broken - no active proteins because the number of repeats is so large that it can't be read through. > >Usually these types of mutations are found in the promoter regions of a gene - tho sometimes in introns... so they aren't mendelian in inheritance pattern on top of all that, but I digress. >The nice thing with this is that if the parents know the number of repeats they had in their genetics (say in a shadowrun type universe) the break down is mathematical and basically mendelian (sort of, there are always exceptions)... you get weird punnett squares if you try to model it but you can get them... where one person has 3 or more possiblities for the state of a chromosome and the other has one or two (like a normal gene). >-Sue
Ok, so how would it break down and what would be the math behind it (more or less)? :) _______________________________________________ GurpsNet-L mailing list <[email protected]> http://mail.sjgames.com/mailman/listinfo/gurpsnet-l
