If you need a good MOSFET with a low Vgs(on), consider the DMN6040SVT. It 
has a low Rds(on), around 60 milliohms. My wristwatch uses this for the 
DC-DC converter for these reasons, and also because it has very low 
leakage. I drive the gate at 3.2V .

BUT.....if you use this device, you must use a transformer (basically 2 
coupled inductors), to reduce the "kickback" spike that occurs while the HV 
cap is charging. The DMN6040SVT will only tolerate 60V, so if you want to 
generate 180V, you will want a transformer that is at least a 4:1 turns 
ratio. Mine is 10:1 .

Finding low Vgs(on) devices with a high Vds is difficult; there are not 
very many and this was the best one I could find for my application.

You may want to look into circuit changes that will give you a higher Vgs.

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