malah makin bingung. di wiki pun nggak ada beda yang jelas. intinya adalah,
mereka bisa membedakan mana yang benar dan mana yang salah, they just don't
care.
Portrait of a 
sociopath<http://www.sociopathworld.com/p/portrait-of-sociopath.html>
  From Craig, M., Catani, M., Deeley, Q., Latham, R., Daly, E., Kanaan, R.,
Picchioni, M., McGuire, P., Fahy, T., & Murphy, D. (2009). Altered
connections on the road to psychopathy Molecular Psychiatry, 14 (10),
946-953 DOI: 10.1038/mp.2009.40

The manipulative con-man. The guy who lies to your face, even when he
doesn’t have to. The child who tortures animals. The cold-blooded killer.
Psychopaths are characterised by an absence of empathy and poor impulse
control, with a total lack of conscience. About 1% of the total population
can be defined as psychopaths, according to a detailed psychological profile
checklist. They tend to be egocentric, callous, manipulative, deceptive,
superficial, irresponsible and parasitic, even predatory. The majority of
psychopaths are not violent and many do very well in jobs where their
personality traits are advantageous and their social tendencies tolerated.
However, some have a predisposition to calculated, “instrumental” violence;
violence that is cold-blooded, planned and goal-directed. Psychopaths are
vastly over-represented among criminals; it is estimated they make up about
20% of the inmates of most prisons. They commit over half of all violent
crimes and are 3-4 times more likely to re-offend. They are almost entirely
refractory to rehabilitation. These are not nice people.

So how did they get that way? Is it an innate biological condition, a result
of social experience, or an interaction between these factors? Longitudinal
studies have shown that the personality traits associated with psychopathy
are highly stable over time. Early warning signs including
“callous-unemotional traits” and antisocial behaviour can be identified in
childhood and are highly predictive of future psychopathy. Large-scale twin
studies have shown that these traits are highly heritable – identical twins,
who share 100% of their genes, are much more similar to each other in this
trait than fraternal twins, who share only 50% of their genes. In one study,
over 80% of the variation in the callous-unemotional trait across the
population was due to genetic differences. In contrast, the effect of a
shared family environment was almost nil. Psychopathy seems to be a lifelong
trait, or combination of traits, which are heavily influenced by genes and
hardly at all by social upbringing.

The two defining characteristics of psychopaths, blunted emotional response
to negative stimuli, coupled with poor impulse control, can both be measured
in psychological and neuroimaging experiments. Several studies have found
decreased responsiveness of the amygdala to fearful or other negative
stimuli in psychopaths. They do not seem to process heavily loaded emotional
words, like “rape”, for example, any differently from how they process
neutral words, like “table”. This lack of response to negative stimuli can
be measured in other ways, such as the failure to induce a galvanic skin
response (heightened skin conduction due to sweating) when faced with an
impending electrical shock. Psychopaths have also been found to
underactivate limbic (emotional) regions of the brain during aversive
learning, correlating with an insensitivity to negative reinforcement. The
psychopath really just doesn’t care. In this, psychopaths differ from many
people who are prone to sudden, impulsive violence, in that those people
tend to have a hypersensitive negative emotional response to what would
otherwise be relatively innocuous stimuli.

What these two groups have in common is poor impulse control. This faculty
relies on the part of the brain called the prefrontal cortex, most
particularly the orbitofrontal cortex. It is known that lesions to this part
of the brain impair planning, prediction of consequences, and inhibition of
socially unacceptable behaviour – the cognitive mechanisms of “free won’t”,
rather than free will. This brain region is also normally activated by
aversive learning, and this activation is also reduced in psychopaths. In
addition, both the prefrontal cortex and the amygdala show substantial
average reductions in size in psychopaths, suggesting a structural
difference in their brains.

These findings have now been united by a recent study that directly analysed
connectivity between these two regions. Using diffusion tensor imaging (see
post of August 31st 2009), Craig and colleagues found that a measure of the
integrity of the axonal tract connecting these two regions, called the
uncinate fasciculus, was significantly reduced in psychopaths. Importantly,
connectivity of these regions to other parts of the brain was normal. These
data thus suggest a specific disruption of the network connecting
orbitofrontal cortex and amygdala in psychopaths, the degree of which
correlated strongly with the subjects’ scores on the psychopathy checklist.

All of these findings are pointing to a picture of psychopathy as an innate,
genetically driven difference in connectivity between parts of the brain
that normally drive empathy, conscience and impulse control. Not a fault
necessarily, and not something that could be classified as a disease or that
is always a disadvantage. At a certain frequency in the population, the
traits of psychopathy may be highly advantageous to the individual.

This conclusion has serious ethical and legal implications. Could a
psychopath mount a legal defense by saying “my brain made me do it”? Or my
“genes made me do it”? Is this any different from saying my rotten childhood
made me do it? Psychopaths know right from wrong – they just don’t care.
That is what society calls “bad”, not “mad”. But if they are
constitutionally incapable of caring, can they really be blamed for it? On
the other hand, if violent psychopaths are a continuing danger to society
and completely refractory to rehabilitation, what is to be done with them?
Perhaps, as has been proposed in the UK, people with the extreme
psychopathic personality profile (or maybe in the near future even a
specific genetic profile?) should be monitored or segregated even before
they commit a crime.

While it is crucial that these debates are informed by good science, these
issues have no clear-cut answers. They will be resolved on a pragmatic
basis, weighing the behaviour that society is willing to tolerate versus the
rights of the individual, whatever their brains look like, to define their
own moral standards.


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http://ryosaeba.wordpress.com/2010/08/16/membedah-artikel-jiplakan-di-koran-anak-indonesia/

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