Hello,
I also can't get msconvert to perform peak picking from an MGF file.
Is that possible?
I'm experimenting with signal profile modelling and thus need a tool
for converting a calculated profile into a peak list. Of course, since
the signal isn't obtained with any instrument, I don't use any vendor
libraries, either.
I tried packing the profile data into mzXML as a binary insertion, but
peak picking with msconvert from mzXML doesn't work so far: no peaks
are detected. What can be the problem?

On Feb 10, 10:42 pm, Joe Slagel <[email protected]> wrote:
> I believe it is available using peakPicking true, but you can confirm by
> forwarding your question on the Proteowizard mailing list as they are the
> developers of msconvert.
>
> https://lists.sourceforge.net/lists/listinfo/proteowizard-support
>
>
>
> On Thu, Feb 10, 2011 at 11:19 AM, John Prince <[email protected]> wrote:
> > Is centroiding (peak picking) without vendor software implemented?
>
> > The interface for doing this is clearly suggested in the msconvert
> > help:
> >    peakPicking prefer_vendor:<true|false>  int_set(MS levels)
>
> > I run this kind of command on a system without thermo libraries:
> >    ./pwiz_bin/msconvert Hek_cells_100904050914.mzXML --mzXML -z --
> > filter "peakPicking false [1]" -o centroided_by_pwiz
>
> > It generates an output file that is identical to the profile file, but
> > with the added line:
> >    <dataProcessing centroided="1">
>
> > So, it would appear that no vendor-less centroiding is yet
> > implemented.  Can this be confirmed?
>
> > Much thanks for all the hard work on an outstanding tool set in
> > general.
>
> > --John
>
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> --
> Joe Slagel
> Institute for Systems Biology
> [email protected]
> (206) 732-1362

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