Hi,
I think you dont need to convert mascot .dat files to pepxml using 
Mascot2XML, you can directly run xinteract which takes care of the 
conversions. It should go something like:

xinteract -D/full/path/database -e(enzyme; T for Trypsin) (generaloptions) 
-O(prophetoptions) -Noutput.pep.xml summary1.dat summary2.dat....

I generally have the mzXML files in the same directory or I make a soft 
link in the search directory pointing to the original mzXML files. I dont 
think you can have mgf files because, if I am not wrong, mgf files dont 
store MS info.

I am fairly new with TPP so apologies if I have said anything wrong. Also 
note that I use the linux version of TPP.

Cheers,
Kshitiz

On Monday, June 27, 2011 10:45:37 PM UTC+1, Dhruti wrote:
>
> I tried to convert Mascot DTA to pepXML using MASCOT2XML program 
> without any success. I get following error 
>
>     c:/Inetpub/wwwroot/ISB/data/F002856.pep.xml [ Unreadable! ] 
>     c:/Inetpub/wwwroot/ISB/data/F002857.pep.xml [ Unreadable! ] 
>
> un_in c:/Inetpub/wwwroot/ISB/data; c:\Inetpub\tpp-bin\Mascot2XML c:/ 
> Inetpub/wwwroot/ISB/data/F002856.dat  -Dc:/Inetpub/wwwroot/ISB/data/ 
> dbase/uniprot_trembl.fasta -pI -Etrypsin -notgz -desc -shortid 
>
> command "c:\Inetpub\tpp-bin\Mascot2XML c:/Inetpub/wwwroot/ISB/data/ 
> F002856.dat -Dc:/Inetpub/wwwroot/ISB/data/dbase/uniprot_trembl.fasta - 
> pI -Etrypsin -notgz -desc -shortid" failed: Unknown error 
>
> Command FAILED 
>
> THe Dta was generated by searching  thermo  raw files using MASCOT 
> 2.3. 
>
> THanks

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