Thank you.Will look into the parameters again.

Regards,
Rishika


On Tue, Aug 13, 2013 at 4:35 PM, David Shteynberg <
[email protected]> wrote:

> Usually when the search returns no good results (which is what TPP is
> telling you here) it is one of three possible options:
>
> 1.  Bad data quality
> 2.  Wrong search parameters (incorrect static mass mod or wrong enzyme
> info. etc)
> 3.  Wrong database (incorrect organism etc)
>
> Please consider these possibilities in your search results.
>
> -David
>
>
> On Tue, Aug 13, 2013 at 12:00 PM, Rishika Bisaria <[email protected]
> > wrote:
>
>> I am sorry but I am really very new to Proteomics and I am not able to
>> figure out the reason for error.
>>
>>
>>
>>
>> On Tue, Aug 13, 2013 at 2:56 PM, David Shteynberg <
>> [email protected]> wrote:
>>
>>> Any reason you would see this other than Tandem search failed to
>>> generate results?
>>>
>>> Parsing search results "SP062512_062912_IP0201_AX01_23to24 (X! Tandem
>>> (k-score))"...
>>>   => Total of 0 hits.
>>>   => Total of 0 decoy hits.
>>>   => Total of 0 excluded hits.
>>>
>>>
>>> On Tue, Aug 13, 2013 at 11:41 AM, Rishika Bisaria <
>>> [email protected]> wrote:
>>>
>>>> Hi,
>>>> Thank you for the reply.
>>>> Actually I want to follow this pipeline:
>>>>
>>>> Tandem->peptideprophet->q3new->proteinprophet->Q3proteinRatioParser.
>>>>
>>>> And also when I am using Xinteract , I am getting the below error:
>>>>
>>>> running: "C:/Inetpub/tpp-bin/ProphetModels.pl -i
>>>> interact.iproph.pep.xml"
>>>> Analyzing interact.iproph.pep.xml ...
>>>> Reading NSS model  ...
>>>> Reading NRS model  ...
>>>> Reading NSE model  ...
>>>> Reading NSI model  ...
>>>> Reading NSM model  ...
>>>> Reading NSP model  ...
>>>> Parsing search results "SP062512_062912_IP0201_AX01_23to24 (X! Tandem
>>>> (k-score))"...
>>>>   => Total of 0 hits.
>>>>   => Total of 0 decoy hits.
>>>>   => Total of 0 excluded hits.
>>>> command completed in 1 sec
>>>>
>>>> running: "c:/Inetpub/wwwroot/../tpp-bin/PepXMLViewer.cgi -I
>>>> c:/xtandem/interact.iproph.pep.xml"
>>>>
>>>> command "c:/Inetpub/wwwroot/../tpp-bin/PepXMLViewer.cgi -I
>>>> c:/xtandem/interact.iproph.pep.xml" failed: Unknown error
>>>>
>>>> command "c:/Inetpub/wwwroot/../tpp-bin/PepXMLViewer.cgi -I
>>>> c:/xtandem/interact.iproph.pep.xml" exited with non-zero exit code:
>>>> -1073741819
>>>> QUIT - the job is incomplete
>>>>
>>>>
>>>>
>>>>
>>>>
>>>> On Tue, Aug 13, 2013 at 2:28 PM, David Shteynberg <
>>>> [email protected]> wrote:
>>>>
>>>>> You pipeline is missing the InteractParser step.  Once you have a
>>>>> pep.xml file from Tandem you can run "xinteract -ip -p0 "on it to generate
>>>>> InteractParser->PeptideProphet->iProphet->ProteinProphet pipeline results.
>>>>>
>>>>> -David
>>>>>
>>>>>
>>>>> On Tue, Aug 13, 2013 at 10:16 AM, Rishika Bisaria <
>>>>> [email protected]> wrote:
>>>>>
>>>>>> Hi,
>>>>>> I am able to run successfully the TPP pipeline on one of the mzXML
>>>>>> file.But on using TPP on other mzXML file , ProteinProphet is throwing
>>>>>> error stating that did you forgot to run PeptideProphet.
>>>>>> I have crossed checked all the parameters , they are correct.I am
>>>>>> using the latest version of TPP on windows and running it using 
>>>>>> commandline.
>>>>>>
>>>>>> 1.tandem input.xml
>>>>>> 2.Tandem2XML output.2013_07_24_13_24_28.t.xml
>>>>>> output.2013_07_24_13_24_28.pep.xml
>>>>>> 3.PeptideProphetParser output.2013_07_24_13_24_28.pep.xml MINPROB=0.2
>>>>>> 4.ProteinProphet output.2013_07_24_13_24_28.pep.xml
>>>>>>  c:\Inetpub\wwwroot\out1.prot.xml
>>>>>>
>>>>>> ****
>>>>>>
>>>>>> P.S. Everytime I am changing the parameters in input.xml file.I am
>>>>>> using k-score function.
>>>>>>
>>>>>>
>>>>>> Thanks,
>>>>>> Rishika
>>>>>>
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