Hi Mike,

Thanks for the clarification. I've sent the folks at ProteoWizard an 
e-mail. Anything I learn I'll post in the forum.

Best,

Adam

On Monday, July 30, 2018 at 7:10:23 PM UTC-5, Michael Hoopmann wrote:
>
> Hi Adam,
> Yes, that is the linux compatible driver. Specifically, it works through 
> Mono. However, I'm not sure if any existing converters have been updated to 
> make use of it. msconvert is maintained by ProteoWizard, and it might be 
> best to see if they have a linux version that uses those drivers. I am not 
> sure what VM we use for our msconvert via linux, but perhaps someone else 
> on this board knows.
> Cheers,
> Mike
>
> On Monday, July 30, 2018 at 12:54:45 PM UTC-7, Adam Rabalski wrote:
>>
>> Hi Mike,
>>
>> Do you know if this has changed recently? I see that Thermo has a 
>> RawFileReader that they say is compatible with linux now 
>> http://planetorbitrap.com/rawfilereader#.W19raqdKi71 Is this the linux 
>> compatible driver you speak of? Is there a msconvert version that can take 
>> the vendor library from thermo and convert raw -> mzML in linux? Or is this 
>> still only possible through mono or a windows vm? How does your group at 
>> ISB handle this and which VM setup do you recommend?
>>
>> Best,
>>
>> Adam
>>
>> On Saturday, June 2, 2018 at 11:06:48 AM UTC-5, Michael Hoopmann wrote:
>>>
>>> No, there isn't a native tool for Linux that reads vendor formats. 
>>> Unfortunately, vendor formats are proprietary and requires the vendor 
>>> drivers to access those files and convert them. All of those drivers are 
>>> Windows only, as the vendors have decided that is their platform of choice. 
>>> Thermo will eventually release a Linux compatible driver set for Mono, 
>>> maybe you can even get your hands on the development version - but it will 
>>> only read the file. Converting it to another format will require additional 
>>> coding or interfacing with ProteoWizard.
>>>
>>> One possible solution would be to create a Windows virtual machine for 
>>> converting vendor formats. It can be fired up inside Linux, then convert 
>>> the vendor files to mzML using msconvert from ProteoWizard, copy the mzML 
>>> files back to your Linux filesystem, and wind down the VM.
>>>
>>> Cheers,
>>> Mike
>>>
>>>

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