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> > On Wednesday 05 July 2006 14:18, Eleanor Dodson wrote:
> > I dont think that sort of Rfactor/Rfree difference at 2.7A is very
> > surprising..
>
> I disagree - although not surprising at this resolution, this gap in Rfactors
> is almost certainly a sign of overfitting. If I were to referee a manuscript
Disagreeing with the referees is dangerous, but disagreeing with Eleanor
is even worse ;-)
Nicholas
--
Dr Nicholas M. Glykos, Department of Molecular
Biology and Genetics, Democritus University of Thrace,
Dimitras 19, 68100 Alexandroupolis, GREECE, Fax ++302551030613
Tel ++302551030620 (77620), http://www.mbg.duth.gr/~glykos/
