Nicholas M Glykos wrote:

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On Wednesday 05 July 2006 14:18, Eleanor Dodson wrote:
I dont think that sort of Rfactor/Rfree difference at 2.7A is very
surprising..
I disagree - although not surprising at this resolution, this gap in Rfactors is almost certainly a sign of overfitting. If I were to referee a manuscript

Disagreeing with the referees is dangerous, but disagreeing with Eleanor is even worse ;-)

Nicholas


Please disagree as often as necessary!
Eleanor
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