In January of 2018, you added an article on Joseph Dougherty, the Canadian
buried in the Grange. His sister was my grandmother, Martha Doherty Clements
who lived at Lower Tully across the border in Londonderry before emigrating
to Canada.

Based on medical reactions and testing of descendants in both families,
Joseph and Martha were carriers of a genetic condition, known as malignant
hyperthermia or MH.  The University of Cork has centre for study of this
condition which is known in Irish families. It is an autosomal dominant
condition. DNA testing is not  definitive and muscle biopsies are often
used.

Links for description
https://en.wikipedia.org/wiki/Malignant_hyperthermia
https://www.mayoclinic.org/diseases-conditions/malignant-hyperthermia/symptoms-causes/syc-20353750

Until surgery under anesthetic became common, this condition was unknown.

The condition would have come from one of Joseph's parents either William
Doherty (1842-1926) or  Jane Thompson(1849-1945).  William's parents were
William Doherty and Peggy Dunn ( no data, haven't searched).  Jane's
parents were Nathaniel Thompson and Martha Martin( no data, haven't
searched).

I'm interested in knowing whether there are other descendant families who
may have condition whether they know it or not.

Dave Clements
Bowmanville, ON
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