2017-10-30 14:58 GMT+01:00 PGC <[email protected]>:

> On Sunday, October 29, 2017 at 6:40:53 PM UTC+1, Bruno Marchal wrote:
>>
>>
>> Right.
>>
>>
>>
>> In acute, severe pain they are often the only thing that works, and
>> denying them to a suffering patient is inhumane. In chronic pain, their use
>> is more controversial. Perhaps not widely known is that in a way they are
>> very safe drugs in that they do not cause end organ damage, unlike, say,
>> alcohol or tobacco.
>>
>>
>> Note that tobacco would be much less dangerous if people were informed,
>> and could have more choice. Since tobacco exists, it has been used orally
>> by many people, and today, studies shows that this mode of consumption is
>> far less dangerous than smoking it.
>>
>>
>>
>>
>> Elephant-killing doses of fentanyl are used in cardiac surgery, and as
>> long as respiration is supported, the patient wakes up fine. The problem is
>> that some people (not all) enjoy the euphoric effect so much that they
>> misuse them, leading to tolerance, dose escalation and risk of overdose.
>>
>>
>> That is right, but seems to be an effect of its prohibition.
>>
>
> Then next time a person requires that kind of surgery, they can thus
> inform the doctor that a small salvia infusion and some chewing tobacco
> suffices for their analgesic needs before a scalpel is reached for? The
> efficacy of opiates is not merely an effect of prohibition.
>
> Assuming something severe like heart surgery, a work related accident, a
> soldier being exposed to an IED and losing a limb in a war zone... anywhere
> where high levels of pain are a clear matter, I know why most humane
> doctors today turn to opiates. Efficacy at pain management. Stathis is
> correct.
>
> In addition to their utility in surgery, it is a fact that said soldier
> with a lost limb, supplied with an appropriate dose of morphine, fentanyl,
> or one of its equivalents may not have their mortifying/traumatic level of
> pain disappear completely; i.e. the pain is still there but somehow, from a
> subjective point of view, *it matters much less than before the opiate
> was administered*. If pain is assumed to be nature's "argument of
> authority", then opiates are the best local god atm. This property is
> remarkable, useful, and well established. You could argue that some of the
> dynamics of prohibition are due to opiates' efficacy: they are so effective
> at relieving pain that people have waged war over their control/use.
>
>
>> In the city of Liege, in Belgium, they have made (two times) a three year
>> experience of legalizing heroin. You need a medical prescription. This has
>> confirmed that the best medication to quit heroin is ... heroin itself,
>> when cheap and medically prescribed. heroin then loose completely its
>> appeal for "beginners", and old consummers, not only get fine, got the time
>> to search a job, diminish by themselves the consumption, and eventually
>> most have stopped. Obviously, this is helpful for getting clean needles and
>> preventing AIDS. Despite this success, heroin is still illegal in Belgium,
>> for pure insane political reason.
>>
>
> What's so insane about the usual social dynamics of loosing face or being
> in office? Assuming you had a sizable bit of political reputation to
> uphold, would you risk it by switching sides on something that is clearly
> not decidable in public? Betting on your aesthetic preference for
> everything minimalism, you'd choose the path of minimal risk and uphold the
> very prohibition you flatter yourself denouncing.
>
> Because it's much easier to yodel conspiracy from the outside than to face
> the practicalities and admit the tension of two opposing facts:
>
> 1) Opiates are the most effective tools for pain management known, and
> their usefulness in surgery is well established, so we need them for now.
> 2) With chronic pain, it is often impossible to distinguish between those
> that are "truly suffering from consistent and/or worsening pain" and those
> that want access to the drug for whatever reason (which the Christians
> demonize because they loose subscribers). All copies state that they are in
> severe pain for true reasons in their history. Unfortunately, interviewing
> them in a thought experiment sheds no light on the matter. Some of them
> will die of overdose and respiratory failure.
>
>
>>
>> Note that heroin was first sold in Germany to cure young infant cough.
>>
> Its illegality is one of the most source of finance of terrorism, and in
>> this case there are proof that the CIA have organized traffic. It seems
>> also that it is part of the reason the american have gone to Afghanistan
>> (to protect the field of Opiate-plant (Pavot, in french). I have verified
>> this, but it does not obvious to interpret all data; need to pursue the
>> research.
>>
>
> By all means do so with a bit more rigor. This list is a place where
> wishful thinking is shared most liberally, but I do know that some folks
> read and interpret it literally and when I saw "Analgesic effect of opiates
> is a result of its prohibition"
>

Hi, I will only answer to this, as I think that's not what Bruno said, if
you reread the sentence here:

> The problem is that some people (not all) enjoy the euphoric effect so
>> much that they misuse them, leading to tolerance, dose escalation and risk
>> of overdose.
>>
>>
>> That is right, but seems to be an effect of its prohibition.
>>
>
I think "seems to be an effect of its prohibition" refers to the misuse and
dose escalation, and not to the analgesic effect which would be false of
course...

Quentin


> today, then somebody should beg to differ because this wishful thinking
> could be mistaken for medically sound advice. Concerning management of
> acute and severe pain, it is not only useless but may result in people
> suffering needlessly: If you are in Belgium and are faced with the
> misfortune of having to choose how to manage acute severe pain, I would be
> skeptical/unconvinced of using cannabis, hallucinogens, or salvia; I'd go
> with something like Piritramide and get some recovery and rest. Inform the
> CIA they have to be quicker and less obvious.
>
>
>>
>> In Russia, they have try to eradicate heroin in a large part of the
>> country. the result is the apparition of the drug Krokodil. That one is
>> total poison, in horrible pain and always leading to long agony and death
>> ...
>>
>> No medication at all should be demonized.
>>
>
> You just demonized Krokodil. One line above.
>
>
>> To use a drug/medication concerns only you and/or you shaman/doctor.
>>
>
> Well if said doctor advises you to chew tobacco before heart surgery, then
> I think it should be clear what kind of shaman that is. PGC
>
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