On Monday, October 30, 2017 at 3:08:58 PM UTC+1, Quentin Anciaux wrote:
>
>
>
> 2017-10-30 14:58 GMT+01:00 PGC <[email protected] <javascript:>>:
>
>> On Sunday, October 29, 2017 at 6:40:53 PM UTC+1, Bruno Marchal wrote:
>>>
>>>
>>> Right.
>>>
>>>
>>>
>>> In acute, severe pain they are often the only thing that works, and 
>>> denying them to a suffering patient is inhumane. In chronic pain, their use 
>>> is more controversial. Perhaps not widely known is that in a way they are 
>>> very safe drugs in that they do not cause end organ damage, unlike, say, 
>>> alcohol or tobacco.
>>>
>>>
>>> Note that tobacco would be much less dangerous if people were informed, 
>>> and could have more choice. Since tobacco exists, it has been used orally 
>>> by many people, and today, studies shows that this mode of consumption is 
>>> far less dangerous than smoking it.
>>>
>>>
>>>
>>>
>>> Elephant-killing doses of fentanyl are used in cardiac surgery, and as 
>>> long as respiration is supported, the patient wakes up fine. The problem is 
>>> that some people (not all) enjoy the euphoric effect so much that they 
>>> misuse them, leading to tolerance, dose escalation and risk of overdose.
>>>
>>>
>>> That is right, but seems to be an effect of its prohibition.
>>>
>>
>> Then next time a person requires that kind of surgery, they can thus 
>> inform the doctor that a small salvia infusion and some chewing tobacco 
>> suffices for their analgesic needs before a scalpel is reached for? The 
>> efficacy of opiates is not merely an effect of prohibition. 
>>
>> Assuming something severe like heart surgery, a work related accident, a 
>> soldier being exposed to an IED and losing a limb in a war zone... anywhere 
>> where high levels of pain are a clear matter, I know why most humane 
>> doctors today turn to opiates. Efficacy at pain management. Stathis is 
>> correct. 
>>
>> In addition to their utility in surgery, it is a fact that said soldier 
>> with a lost limb, supplied with an appropriate dose of morphine, fentanyl, 
>> or one of its equivalents may not have their mortifying/traumatic level of 
>> pain disappear completely; i.e. the pain is still there but somehow, from a 
>> subjective point of view, *it matters much less than before the opiate 
>> was administered*. If pain is assumed to be nature's "argument of 
>> authority", then opiates are the best local god atm. This property is 
>> remarkable, useful, and well established. You could argue that some of the 
>> dynamics of prohibition are due to opiates' efficacy: they are so effective 
>> at relieving pain that people have waged war over their control/use.
>>  
>>
>>> In the city of Liege, in Belgium, they have made (two times) a three 
>>> year experience of legalizing heroin. You need a medical prescription. This 
>>> has confirmed that the best medication to quit heroin is ... heroin itself, 
>>> when cheap and medically prescribed. heroin then loose completely its 
>>> appeal for "beginners", and old consummers, not only get fine, got the time 
>>> to search a job, diminish by themselves the consumption, and eventually 
>>> most have stopped. Obviously, this is helpful for getting clean needles and 
>>> preventing AIDS. Despite this success, heroin is still illegal in Belgium, 
>>> for pure insane political reason.
>>>
>>  
>> What's so insane about the usual social dynamics of loosing face or being 
>> in office? Assuming you had a sizable bit of political reputation to 
>> uphold, would you risk it by switching sides on something that is clearly 
>> not decidable in public? Betting on your aesthetic preference for 
>> everything minimalism, you'd choose the path of minimal risk and uphold the 
>> very prohibition you flatter yourself denouncing.
>>
>> Because it's much easier to yodel conspiracy from the outside than to 
>> face the practicalities and admit the tension of two opposing facts:
>>
>> 1) Opiates are the most effective tools for pain management known, and 
>> their usefulness in surgery is well established, so we need them for now.
>> 2) With chronic pain, it is often impossible to distinguish between those 
>> that are "truly suffering from consistent and/or worsening pain" and those 
>> that want access to the drug for whatever reason (which the Christians 
>> demonize because they loose subscribers). All copies state that they are in 
>> severe pain for true reasons in their history. Unfortunately, interviewing 
>> them in a thought experiment sheds no light on the matter. Some of them 
>> will die of overdose and respiratory failure.
>>  
>>
>>>
>>> Note that heroin was first sold in Germany to cure young infant cough. 
>>>
>> Its illegality is one of the most source of finance of terrorism, and in 
>>> this case there are proof that the CIA have organized traffic. It seems 
>>> also that it is part of the reason the american have gone to Afghanistan 
>>> (to protect the field of Opiate-plant (Pavot, in french). I have verified 
>>> this, but it does not obvious to interpret all data; need to pursue the 
>>> research.
>>>
>>
>> By all means do so with a bit more rigor. This list is a place where 
>> wishful thinking is shared most liberally, but I do know that some folks 
>> read and interpret it literally and when I saw "Analgesic effect of opiates 
>> is a result of its prohibition"
>>
>
> Hi, I will only answer to this, as I think that's not what Bruno said, if 
> you reread the sentence here:
>
>> The problem is that some people (not all) enjoy the euphoric effect so 
>>> much that they misuse them, leading to tolerance, dose escalation and risk 
>>> of overdose.
>>>
>>>
>>> That is right, but seems to be an effect of its prohibition.
>>>
>>
> I think "seems to be an effect of its prohibition" refers to the misuse 
> and dose escalation, and not to the analgesic effect which would be false 
> of course...
>

Valiant try for a save but merely a variant of the same distortion of 
facts: the misuse and dose escalation is not merely an effect of 
prohibition.The misuse and dose escalation is due to what opiates are: 
extremely effective at treating pain. See reports of pre-prohibition opium 
use. Their attraction is well documented before prohibition.

You might argue that prohibition sharpens this needlessly but this still 
won't bring about a general, more careful attitude towards their use in 
populations currently affected by high death rates. PGC

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