The problem is, Mr. D. is that he peeps on the mailing list here go by ideology 
and the ideology is Progressive, where human concerns be damned ideological 
faith and loyalty is #1. It's not about the science it's about the "faith." For 
me personally? I am a Pfizer enthusiast, unsure of Moderna, and in both cases 
worried about young people croaking without cause. Please note, that these guys 
rock when discussing Alice & Bob experiments, but simply cannot let their 
emotions be uncontrolled when dealing outside their ideology. 
Me? A bit different. For politics, I switched from Trumpo to DeSantis for 2 
reasons, which are, Trump couldn't prove election fraud, and DeSantis does so 
more, with so much less. He is my Go-To guy. He is also not the ego that Donny 
was. Could I ever vote Dem again? Maybe, but they'd have to be better than the 
progressive and globalist scuzzos that proggies are now.
Policies are the only things that matter. So..For me?Good on Vaxing, but good 
on seeing for bad side effects.Good on solar. But interested in other energy 
makers.Likes battery power.Good on doing space mining as a economic and social 
fix.Good on Basic research funding but see engineering to be made real. If lab 
stuff stays in the lab, meh!Other policies can get argued later.Foreign 
Policies-Afraid of Putin and Xi. See these as a deliberately existential 
threat. 
But that's on just me, and I try not to get beyond tech, or cosmology, which is 
more, uplifting.
Spud. 


-----Original Message-----
From: Dylan Distasio <[email protected]>
To: [email protected]
Sent: Sat, Dec 17, 2022 6:01 pm
Subject: Re: Death, science, and politics

There are plenty of reputable researchers and MDs who have raised concerns over 
the safety of mRNA nanoparticles as a delivery vehicle; it's not necessary to 
go to the Epoch times to find these concerns, and it's not a conspiracy theory.
It is pretty clear at this point that the nanoparticles in many cases do not 
stay localized and get into other tissues.   In fact, a tissue distribution 
study in animals is in the original application paperwork which shows that the 
nanoparticle delivery system goes to nearly every tissue in the body.   No 
studies on tissue distribution of the nanoparticles WITH payload, particularly 
in humans, was conducted to my knowledge prior to approval which is a big red 
flag.
This is from BMJ which you hopefully hold in higher regard than the Epoch Times:
For COVID-19 mRNA Vaccine (Pfizer or Moderna), the biodistribution studies in 
animals were not conducted. The surrogate studies with luciferase and 
solid-lipid nanoparticles (Pfizer) confirm a biodistribution to the liver and 
other body tissues beyond the administration site [5]. For Moderna, the 
biodistribution of mRNA-1647 (encoding CMV genes) formulated in a similar lipid 
nanoparticulate delivery system confirms a biodistribution beyond the injection 
site, in particular, the distribution to the lymph nodes, spleen and the eye 
was noted [6]. However, the detailed tissue-specific distribution of mRNA 
vaccines encoding SARS-CoV-2 spike proteins (Pfizer or Moderna) is not fully 
known that can offer invaluable insights into the potential safety of these 
vaccines in peoples with pre-existing conditions or those on certain 
medications.

The detailed biodistribution data including pharmacokinetics of various CoViD 
vaccines were not conducted by the vaccine manufacturers because the studies 
demonstrating biodistribution of antigens were considered ‘not required' by the 
regulatory authorities on the premise that vaccines work by an immunological 
response than the classic pharmacological approach. However, such an exemption 
may barely justify the conventional vaccines such as those incorporating whole 
inactivated virus, split virion, or the sub-unit vaccines, that directly 
attracts an immune response post-injection.

bmj.com/content/373/bmj.n958/rr-1

There were also modifications made to the mRNA to make it more stable which 
were not tested in humans prior to the initial vaccine trials.
At that point, you have a spike protein (which appears to be toxic in and of 
itself to cells) being potentially distributed via mRNA to multiple tissues 
where beyond causing havoc from production of the spike protein directly, you 
have additional risk of autoimmune disorders occurring.
Caution in widespread rollout of these vaccines would have been advisable, 
particularly when you look at the IFR from Covid-19 in younger, healthy 
cohorts.   This is not conspiracy theory stuff; there are a lot of unknowns 
with this particular tech, and a number of European countries, particularly 
Scandinavian ones, (unlike the US where Big Pharma money talks even more 
loudly) have become more conservative with their recommendations on vaccinating 
/ boosting children.
There was also a concerted effort from government and the press to block all 
discussion on these potential risks, and to destroy the livelihood of anyone 
who raised them.   This is not the way science is supposed to be conducted.
We were also told in the beginning by US government agencies (it's on the 
record if you care to look it up) that these vaccines would do a very good job 
of stopping transmission.   We all know now that was a falsehood as they are 
incredibly leaky.
In aggregate, there are a large number of troubling red flags over how this 
rollout was handled by various government agencies.   It should not have been a 
one size fits all solution based on disparate IFRs in different cohorts based 
on age/comorbidities combined with very leaky vaccines, and there certainly 
shouldn't have been any mandates.
This is another more recent note published in the BMJ discussing risk/reward in 
younger cohorts:COVID-19 vaccine boosters for young adults: a risk benefit 
assessment and ethical analysis of mandate policies at universities

Abstract
In 2022, students at North American universities with third-dose COVID-19 
vaccine mandates risk disenrolment if unvaccinated. To assess the 
appropriateness of booster mandates in this age group, we combine empirical 
risk-benefit assessment and ethical analysis. To prevent one COVID-19 
hospitalisation over a 6-month period, we estimate that 31 207–42 836 young 
adults aged 18–29 years must receive a third mRNA vaccine. Booster mandates in 
young adults are expected to cause a net harm: per COVID-19 hospitalisation 
prevented, we anticipate at least 18.5 serious adverse events from mRNA 
vaccines, including 1.5–4.6 booster-associated myopericarditis cases in males 
(typically requiring hospitalisation). We also anticipate 1430–4626 cases of 
grade ≥3 reactogenicity interfering with daily activities (although typically 
not requiring hospitalisation). University booster mandates are unethical 
because they: (1) are not based on an updated (Omicron era) stratified 
risk-benefit assessment for this age group; (2) may result in a net harm to 
healthy young adults; (3) are not proportionate: expected harms are not 
outweighed by public health benefits given modest and transient effectiveness 
of vaccines against transmission; (4) violate the reciprocity principle because 
serious vaccine-related harms are not reliably compensated due to gaps in 
vaccine injury schemes; and (5) may result in wider social harms. We consider 
counterarguments including efforts to increase safety on campus but find these 
are fraught with limitations and little scientific support. Finally, we discuss 
the policy relevance of our analysis for primary series COVID-19 vaccine 
mandates.

https://jme.bmj.com/content/early/2022/12/05/jme-2022-108449

Mandates were unethical in my opinion, and it would appear that at least some 
are waking up to this fact 2+ years later.   I also think it is irresponsible 
to recommend vaccinating children with this tech when there are a lot of 
unknowns and the IFR in children for Covid-19 is miniscule.   For the record, I 
have always been fully supportive of traditional, well tested vaccines that are 
also safe and efficacious.   I also went to school for this stuff and although 
I have long since stopped doing any benchwork or anything else in the field can 
understand basic molecular biology/immunology to have had concerns early on 
with widespread rollout of mRNA tech, particularly when it was being forced on 
people.
On Fri, Dec 16, 2022 at 12:15 PM John Clark <[email protected]> wrote:


Do you really think these risks haven't been investigated 1000 times and the 
answers have come back 1000 times that the benefits of vaccination VASTLY 
outnumber the risks?!  
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