First, Vam, I did not inform D that he was wrong. I informed him that what
he saw on TV was wrong.

"What you saw on TV the other day was implicitly wrong. Prozac is an
SSRI, and has a specific and complex brain functionality."

(typo corrected).

Then I provided a wealth of information which gave the specifics of the
functionality of SSRI's, and their efficacy as compared to placebos. How is
it that you suggest this does not add to the conversation? I believe you
misread my post, my friend.

The placebo effect works with antidepressants because of somatic
manifestation. The patient has psychological issues that they should be
getting counseling for, analysis of some sort, but instead, they internalize
those issue, and begin manifesting physical symptoms in their place. Once
they are given a magic pill for those symptoms, the problem is solved...or
not. Sometimes, they will need to go through a regimen of pills, or stronger
pills...although upon further analysis of prescription history, many MD's
are simply switching out the same type or category of drug (i.e. various
types of fluoxetine (Prozac/Paxil), or substituting a Lamictal/Neurontin
combo for a Topamaxx/Zoloft combo).

http://en.wikipedia.org/wiki/Somatoform_disorder

Common Somatoform (or Somatization) disorders that you may be familiar with
include Fibromyalgia and Chronic Fatigue Syndrome. There is also strong
research showing that chronic lower back pain without causal injury may be
an SD.
On Fri, Aug 7, 2009 at 1:43 PM, Vamadevananda <[email protected]> wrote:

>
> Chris, I found your post informing D how wrong he is !
>
> That really does not add to the discussion. How, according to you,
> forget the statistics, does the the placebo work ?
>
> On Aug 7, 7:29 pm, Chris Jenkins <[email protected]> wrote:
> > What you saw on TV the other day was implicitly wrong. Prozan is an SSRI,
> > and has a specific and complex brain functionality.
> >
> > Additionally, the citation you provided is cleverly styled to appear to
> be
> > the APA website, but by navigating to the root domain, we see that it is
> in
> > actuality a virulently anti-psych website:
> >
> > http://www.antidepressantsfacts.com/
> >
> > This tends to color their data a bit, no?
> >
> > Here are some links to non-biased, peer reviewed studies at PubMed, the
> > general repository for scientific research in the US, directly addressing
> > the question of SSRI versus placebo.
> >
> > http://www.ncbi.nlm.nih.gov/pubmed/11405969?ordinalpos=1&itool=Entrez...
> >
> > http://www.ncbi.nlm.nih.gov/pubmed/19468281?ordinalpos=9&itool=Entrez...
> >
> > http://www.ncbi.nlm.nih.gov/pubmed/18922243?ordinalpos=25&itool=Entre...
> >
> > Here's a great quote:
> >
> > "In a 10-week randomised, double-blind trial in patients with panic
> > disorder, escitalopram (flexible doses 5-10 mg/d) was significantly more
> > effective than placebo in reducing the panic attack frequency, with a
> faster
> > onset of action than citalopram."
> >
> > In fact, in all the studies that I've seen where the efficacy of the
> > medication over placebo dropped to less than 30%, they were 'mild to
> > moderate' cases to begin with.
> >
> > In other words, the Prozac didn't help much because there wasn't much of
> a
> > chemical problem there to help with. Those cases should have been
> referred
> > to psychologists, not psychiatrists. Blaming the medication for not
> fixing a
> > problem that is not chemical in nature is downright silly. There's been a
> > cure for being stressed out and mildly depressed that humans have used
> for a
> > thousand years. It's called three friends and a Pub.
> >
> >
> >
> > On Fri, Aug 7, 2009 at 8:28 AM, deripsni <[email protected]> wrote:
> >
> > > I found this article that claims that the placebo effect accounts for
> > > 50% of the improvement in depressed patients taking anitdepressents,
> > > while only 27% is due to the actual drug. I also saw something on TV
> > > the other day stating that Prozac was basically a sugar coated
> > > placebo. This seems to support a lot of what Molly is saying.
> >
> > >http://www.antidepressantsfacts.com/1996-APA-placebo-vs-SSRI.htm- Hide
> quoted text -
> >
> > - Show quoted text -
> >
>

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