.uk/FBSBM1056>
To access Vacancy Management to view applications etc. use the link below:
https://jobs.leeds.ac.uk/VM/Applications.aspx?jobId=6948
<https://jobs.leeds.ac.uk/VM/Applications.aspx?jobId=6948>
I would be interested in seeing a diverse range of applicants!
Adrian Goldman, P
Molecular Biology. You will be supervised by Professor Adrian
Goldman (SBMS), and the work will involve close collaboration with the
University of Helsinki (Dr Henri Xhaard and Professor Seppo Meri) and with Drs.
Roman Tuma and Sarah Harris at the University of Leeds.
You will be a highly motivated
; Kurt Wüthrich, ETH Zurich
Session speakers include: Riita Hari, Aalto; Edgar Kramer, Hamburg; Carlos
Ibanez, Stockholm; Neil McDonald, Cancer Research, UK; Leo Sazanov,
Cambridge; Ville Kaila, Munich; Adrian Goldman, Leeds; Ulrich Brandt,
Nijmegen; Valerio Carelli, Bologna; Howy Jacobs
Without wishing to get into the terminology, and going back to the OP’s
question: our crystal structures of factor H 19-20 would be a citeable example.
In our hands, the wt 19-20 preferentially crystallises as a well-ordered D2
tetramer (cf Jokiranta et al 2006, EMBO J) that is completely
no, and that’s why they all needed to be stored at Diamond in case future
generations have better programs. And this applies also to those that have
already been digested - I mean, processed.
Adrian
On 01 Apr 2015, at 12:03, Keller, Jacob kell...@janelia.hhmi.org wrote:
Can anyone index
Our recent membrane protein structure (4av3) doesn’t have much in the way of
contacts either, as is characteristic of type 1 membrane protein crystals.
Adrian
On 06 Feb 2015, at 11:51, Andrew Leslie and...@mrc-lmb.cam.ac.uk wrote:
Just to
Well maybe some pressure should be put on Nature to retract the article, so
that we can get the publication out of the PDB? It’s not good that it is there
for the unwary.
Adrian
On 06 Feb 2015, at 11:44, Folmer Fredslund folm...@gmail.com wrote:
and physicists, and as part of the Astbury Centre
for Structural Molecular Biology. You will be supervised by Professor Adrian
Goldman (SBMS).
You will be a highly motivated individual with a strong basis in all aspects of
structural biology from expression to structure determination, and you
.
The applications (in English) should be sent to: Docent Taru Meri, P.O. Box 56,
FIN-00014 UNIVERSITY OF HELSINKI, Finland or by email to taru.m...@helsinki.fi.
The deadline for applications is 4 August 2014.
For more information please contact Adrian Goldman, tel. +44 79 18951821;
adrian.gold
Why not draw out a pasteur pipette using a bunsen burner to the desired
thinness? You’ll end up with something rather like an old-fashioned glass
capillary.
Adrian
On 7 Jul 2014, at 17:52, Matthew Franklin mfrank...@nysbc.org wrote:
Hi Frank -
How about a gel loading pipet tip as a
Well as s/w improvements don't necessarily happen on a yearly basis, but people
like being paid each year, I think the model is not unreasonable, as long as
the cost is reasonable - which, for instance, the Adobe s/w isn't. As one can
tell from the profit margins of s/w companies. So I do pay
and Muench at the addresses
above.
Adrian Goldman and
Stephen Muench
and Muench at the addresses
above.
Adrian Goldman and
Stephen Muench
.
Informal enquiries can be addressed to both Goldman and Muench at the addresses
above.
Adrian Goldman and
Stephen Muench
Hi,
Having now had a chance (finally) to play with the Asus VG27A, I can
say that (a) it works really well in stereo with both Coot and PyMol and (b) it
is easier and nicer to use than the Zalmans.
Though the technology is essentially the same (halving the vertical
Hi,
(and apologies if ANYONE has seen this twice - CCP4BB rejected my first
post as coming from an unknown (i.e. Leeds) address, and the second one because
I had already posted from my Leeds address….)
Here goes:
Having now had a chance (finally) to play with the Asus
…then the issue is to reduce the number of papers people publish: this is the
central problem in the system: nobody reads them, nobody cites them, etc etc.
There are papers out there - quite a number - that have no cites, meaning that
even the authors weren't interested in them. A long time
Yes, my understanding too is that they all work at HD resolution, which is
pretty unimpressive if you halve the vertical frequency. But that's what
constitutes a cheap high-resolution screen this days. One can only wait and
hope that people get into the 4K monitors, when life will become
)”
Linda Olson bought the ASUSVG27AH - and it worked.
hth,
Adrian
Adrian Goldman, Ph. D. |
Leadership Chair in Membrane Biology|
Astbury Centre for Structural Molecular Biology
Astbury 6108b
Hi,
I thought I'd pose my perennial question about 3D-stereo on Macs.
There is the Zalman solution (not terribly good, and are they making monitors
any more?) - are there other vendors doing the same thing? Maybe at higher
resolutions??
In addition, is there any evidence
Hi,
has anyone any joy with stereo visualisation on the mac? There's a
9/2012 note on the PyMOL page indicating that Zalman stereo no longer works on
the MAC, which is certainly my experience: I don't seem t get stereo using Lion
- not in Coot and not in PyMOL.
Is it
I say write them out onto acid-free paper: should be good for at least 300
years without active management, if there is no fire. If that doesn't work, I
believe babylonian clay tablets have an even longer expected life time….
Dale, I must say I am impressed… I gave up after the exabyte to DAT
Don't get your hopes up too high for ssd. I had one fail within 4 months of
buying it - and the company's attitude was 'this sometimes happens'. Yum
I think George is right - punched cards in two separate locations. (Hell any
form of paper output will do - surely they'll have decent OCR in 100
Bernard Dixon is merely copying the great essay by George Orwell 'politics and
the english language'. Its well worth a read.
In it, Orwell lays out about six simple rules for writing good english prose.
Three of them are:
never use the passive voice.
Always use the anglosaxon word instead
.
Adrian Goldman
Adrian Goldman
Institute of Biotechnology, University of Helsinki, Finland
This doesn't really give a useful answer. It tells you the overall
composition, but there is no means of knowing whether the metal ions are
equally present at all sites: some sites can favour Zn over Ca and vice versa.
Flame spectroscopy also works but has the same issue - and both have the
If the data sets are twinned, large differences between derivatives are to be
expected unless the twin fraction is very, very low (1-2%). Given the above,
I think nothing can be said until the data are all detwinned - and of course
the correct axial interchange done.
Adrian
On 30 May 2012,
You can find all the principle investigators you want collecting datums ;) at
the ESRF, as that is how the French spell it on the application form for beam
time! (Unless it has _finally_ been corrected: haven't checked since I
submitted my last BAG application in April.)
I signed, and I think so. Further information can be found here:
http://www.guardian.co.uk/science/2012/feb/02/academics-boycott-publisher-elsevier
On 16 Feb 2012, at 11:41, Boaz Shaanan wrote:
I initially thought that it had to do with a new Hampton Research thing.
But can non-American
Hi,
Just curious if anyone has experience with stereo solutions on the MAC
other than MacPro and stereographics glasses, or the Zalman monitors? Yes, the
Zalman is cheap, and _ok_, but you lose half the horizontal resolution. If the
monitor were 3600x2000 pixels, that wouldn't matter
We had a similar case in our Eib structure (2xzr), with large peaks on a
3-fold. We initially thought it was noise, but Andrei Lupas convinced us to
look more carefully, and it turned out to be chloride ion.
You could do an wavelength scan at a beamline looking for anomalous signal at
the
I agree: light yellow (straw-yellow) proteins often indicate metal-binding -
it's typically iron III. Zn salts tend to be colourless, and the Mn-pink is
too pale to be visible at protein (mM) concentrations. This can be determined
by doing flame-spectroscopy, if you don't mind destroying your
...@helsinki.fi.
Closing date: Wednesday November 30th at 3.45pm EET.
Adrian Goldman |
Research Director and Professor,|
Adjunct professor, Neuroscience Institute |Tel:358-(0)9-191 58923
Macromolecular X-ray Crystallography Group |FAX:358-(0
I have no problem with this idea as an opt-in. However I loathe being forced to
do things - for my own good or anyone else's. But unless I read the tenor of
this discussion completely wrongly, opt-in is precisely what is not being
proposed.
Adrian Goldman
Sent from my iPhone
On 31 Oct
fraction of the terabytes of frame data off the pilots is
needed...
Adrian Goldman
Sent from my iPad
On 27 Oct 2011, at 21:17, Ed Pozharski epozh...@umaryland.edu wrote:
Dear Garib,
I am afraid clarification is in order.
Firstly, the results are available here
https://docs.google.com
an idea just because we think today that 640K is
more memory than anyone will ever need
On Oct 27, 2011, at 3:47 PM, Adrian Goldman wrote:
2) I agree with Susan. In a time of limited funding, is this the most
important use of money?
where my mouth is. Our last five purchases have been i7
iMacs. It seems like quite a nice amount of oomph for the money.
Adrian Goldman
Sent from my iPhone
On 30 Sep 2011, at 19:46, Francis E Reyes francis.re...@colorado.edu wrote:
Bill
Thanks for focusing the thread
to the original
if one wants to do
stereo on MACS...
thanks for comment and advice...
Adrian Goldman
on the zalman as much
(as expected).
HTH,
Sabuj
On Thu, Sep 22, 2011 at 8:22 AM, Sabuj Pattanayek sab...@gmail.com wrote:
Am 22.09.11 11:58, schrieb Adrian Goldman:
Hi,
Anybody having problems with Zalmans and the newer macs? We can't
get the MACS to even _recognise_ the existence
Of course this has to be the case. I think most of us walk around with with
mobile phones that have memory and processing power more powerful than all of
the computers available before 1990.
Some of the things that seem difficult in Lion and are nanny-state-ish such as
automatic file
diligent about
reviewing.
Adrian Goldman
On 12 Aug 2011, at 01:46, Phoebe Rice pr...@uchicago.edu wrote:
Some people on this list seem to think that reviewers are on the whole lazy
and irresponsible and in need of some sort of public ridicule.
Please don't forget that reviewing manuscripts
In my experience, the most common cause of this is the locally correct,
globally wrong issue. You could be in the wrong space group (i.e P21212 when
you should be in P212121). Another possibility is missing some element of
local symmetry. Is the packing in the unit cell appropriate or are
First line up 10^9 poohbears...
Sent from my iPhone
On 22 Apr 2011, at 19:58, Jacob Keller j-kell...@fsm.northwestern.edu wrote:
I think soft crystallography uses fuzzy logic--it's a comforting
alternative to the usual SAD and MAD.
Yes, but this is not how you do it. I assume you have a stereo image to start
with generated from (eg) pymol. and you are trying to float the labels at the
same z as specific
atoms or objects. It is simple. Place the two labels for the two images at
the same y value (y up, x across in my
Just one comment on LEDs as we have them as part of an imaging system. While it
is true that the LEDs themselves emit cool light, the associated electronics is
hotter than I would have expected. FYI.
Adrian
Sent from my iPhone
On 24 Jan 2011, at 19:24, Sampson, Jared jared.samp...@nyumc.org
provides a richly collaborative
environment for studying problems at the interfaces between cell, molecular,
developmental and structural biology. For further information, please contact
Professor Adrian Goldman, Institute of Biotechnology, University of Helsinki.
Email: adrian.gold
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