In the meantime I managed to get all of my 29 files through the
Xtandem pipeline (in tranches of two) up to the point where the pepXML
file is generated (interact.pep.xml). I can look at the data with the
PepXML Viewer and the data look OK (trypsin digest, X! TANDEM
(K-SCORE) search engine, quantitation: [none], displaying 797307 of
797307 total spectra, page 1 of 15947, 329503 unique peptides, 274865
unique stripped peptides, 34263 unique proteins, 5260 single hits),
however, when I try to run ProteinProphet I get a "no data" error
message:

. . . reading in c:/Inetpub/wwwroot/ISB/data/Ooocyte/
20091125_AD_Boiani_oocyte_29.tandem.pep.xml. . .
. . . read in 0 1+, 0 2+, 0 3+, 0 4+, 0 5+, 0 6+, 0 7+ spectra with
min prob 0.05
no data - quittingEND OUTPUT
RETURN CODE:256
###### End Command Execution ######

Does anybody know what to make out of this error massage?

The TPP log file as well as the Xtandem parameter file are uploaded to
ftp://ftp.systemsbiology.net/pub/incoming/  within the Hannes_Xtandem
folder.



On 2 Mrz., 10:53, hcadrexler <[email protected]> wrote:
> Files are now uploaded in one zip file (Hannes_oocyte). Please et me
> know if you need additional information. Good luck!
> Hannes
>
> On 1 Mrz., 16:14, Brian Pratt <[email protected]> wrote:
>
> > Oh, and send the xtandem inputs (mzxml and fasta), not the raw files.
>
> > On Mon, Mar 1, 2010 at 7:14 AM, Brian Pratt 
> > <[email protected]>wrote:
>
> > > Just put it in the pub directory, not a subdirectry.  Consider using
> > > something like gzip to make the files smaller, too.
>
> > > On Mon, Mar 1, 2010 at 2:40 AM, hcadrexler 
> > > <[email protected]>wrote:
>
> > >> Hi Brian,
>
> > >> I just tried to upload a few .raw files and the fasta db into the pub
> > >> folder using filezilla, however, filezilla tells me that I that there
> > >> is no adequate directory for the upload (see error message)??
>
> > >> ..............
> > >> Command:        STOR 
> > >> /pub/Hannes_20100301/20091125_AD_Boiani_oocyte_03.raw
> > >> Response:       550 /pub/Hannes_20100301/ipi.MOUSE.v3.64.fasta: No such
> > >> file
> > >> or directory
> > >> Command:        PASV
> > >> Response:       550 
> > >> /pub/Hannes_20100301/20091125_AD_Boiani_oocyte_03.raw:
> > >> No such file or directory
> > >> Error:  Critical file transfer error
> > >> .............
>
> > >> Kind regards,
>
> > >> Hannes
>
> > >> On 26 Feb., 19:18, Brian Pratt <[email protected]> wrote:
> > >> > Strange indeed.  If you can send me a minimum data set that shows the
> > >> > problem I could take a look (presumably three files and the fasta db).
> > >>  If
> > >> > they're too big to email, you can ftp toftp://
> > >> insilicos.serveftp.net/pub.
> > >> > Brian
> > >> > On Fri, Feb 26, 2010 at 7:10 AM, Hannes Drexler
> > >> > <[email protected]>wrote:
>
> > >> > > Hi Brian,
>
> > >> > > thought about it too, however, when I delete the first two
> > >> > > successfully handled files from the sequence and start the database
> > >> > > search again with the next / third file of the list, the subsequent
> > >> > > two files are also successfully sent through the pipeline. I repeated
> > >> > > it a few more times now and to me it looks like as if XTandem 
> > >> > > database
> > >> > > searches are currently only possible in tranches of two. Strange,
> > >> > > isn´it?
>
> > >> > > Hannes
>
> > >> > > 2010/2/24 Brian Pratt <[email protected]>:
> > >> > >  > You'll want to narrow it down to identify the problem - for
> > >> example,
> > >> > > what
> > >> > > > happens when you omit that 3rd file?
>
> > >> > > > On Wed, Feb 24, 2010 at 2:04 AM, hcadrexler <
> > >> [email protected]>
> > >> > > > wrote:
>
> > >> > > >> Hi there,
>
> > >> > > >> I tried to perform an XTandem search following the XTandem 2009
> > >> > > >> tutorial using my own data (29 mzXML files). The Database search 
> > >> > > >> is
> > >> > > >> performed for the first two files in the sequence without any
> > >> problems
> > >> > > >> but then stops and does not proceed any further with the third 
> > >> > > >> (and
> > >> > > >> subsequent) files. I cannot figure out where the mistake was made.
> > >> > > >> Does anybody know why this might happen?
>
> > >> > > >> Kind regards,
>
> > >> > > >> Hannes
>
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