Did you run peptideProphet before calling ProteinProphet?
On Wed, Mar 10, 2010 at 5:33 AM, hcadrexler <[email protected]>wrote:

> Thanks, Brian,  for your efforts! You may be right regrading the
> browser time out - sounds like a reasonable explanation. I will try
> the command line approach as you suggested.
> The tandem.xml file as well as the log file (HannesTPPlog.txt) are now
> uploaded under my username (hcadrexler) on the groups page file.
>
>
> On 9 Mrz., 23:46, Natalie Tasman <[email protected]> wrote:
> > To distribute your files, you could try posting them on the groups' file
> > page, and then reply with a post containing the filename:
> http://groups.google.com/group/spctools-discuss/files
> >
> > On 3/9/10 2:01 PM, Brian Pratt wrote:
> >
> > > I had a look at the three mzXML files you uploaded to Insilicos -
> > > they're quite large (about 1GB each) and it just takes X!Tandem a long
> > > time to process them.  I suspect that you're only getting two at a
> > > time done in the TPP web interface due to browser timeout, but you can
> > > work around that by copying the contents of the "Attempting to run the
> > > following commands" window to the command line.
> > > As to why you end up with no specta in ProteinProphet - most readers
> > > of this list don't have read access to the ISB ftp site, so you're
> > > better off just attaching files to an email message that everyone can
> > > look at.
> > > Hope this helps,
> > > Brian
> > > On Tue, Mar 9, 2010 at 1:52 AM, hcadrexler <[email protected]
> > > <mailto:[email protected]>> wrote:
> >
> > >     In the meantime I managed to get all of my 29 files through the
> > >     Xtandem pipeline (in tranches of two) up to the point where the
> pepXML
> > >     file is generated (interact.pep.xml). I can look at the data with
> the
> > >     PepXML Viewer and the data look OK (trypsin digest, X! TANDEM
> > >     (K-SCORE) search engine, quantitation: [none], displaying 797307 of
> > >     797307 total spectra, page 1 of 15947, 329503 unique peptides,
> 274865
> > >     unique stripped peptides, 34263 unique proteins, 5260 single hits),
> > >     however, when I try to run ProteinProphet I get a "no data" error
> > >     message:
> >
> > >     . . . reading in c:/Inetpub/wwwroot/ISB/data/Ooocyte/
> > >     20091125_AD_Boiani_oocyte_29.tandem.pep.xml. . .
> > >     . . . read in 0 1+, 0 2+, 0 3+, 0 4+, 0 5+, 0 6+, 0 7+ spectra with
> > >     min prob 0.05
> > >     no data - quittingEND OUTPUT
> > >     RETURN CODE:256
> > >     ###### End Command Execution ######
> >
> > >     Does anybody know what to make out of this error massage?
> >
> > >     The TPP log file as well as the Xtandem parameter file are uploaded
> to
> > >    ftp://ftp.systemsbiology.net/pub/incoming/ within the
> Hannes_Xtandem
> > >     folder.
> >
> > >     On 2 Mrz., 10:53, hcadrexler <[email protected]
> > >     <mailto:[email protected]>> wrote:
> > >     > Files are now uploaded in one zip file (Hannes_oocyte). Please et
> me
> > >     > know if you need additional information. Good luck!
> > >     > Hannes
> >
> > >     > On 1 Mrz., 16:14, Brian Pratt <[email protected]
> > >     <mailto:[email protected]>> wrote:
> >
> > >     > > Oh, and send the xtandem inputs (mzxml and fasta), not the raw
> > >     files.
> >
> > >     > > On Mon, Mar 1, 2010 at 7:14 AM, Brian Pratt
> > >     <[email protected] <mailto:[email protected]
> >>wrote:
> >
> > >     > > > Just put it in the pub directory, not a subdirectry.
> > >      Consider using
> > >     > > > something like gzip to make the files smaller, too.
> >
> > >     > > > On Mon, Mar 1, 2010 at 2:40 AM, hcadrexler
> > >     <[email protected] <mailto:[email protected]
> >>wrote:
> >
> > >     > > >> Hi Brian,
> >
> > >     > > >> I just tried to upload a few .raw files and the fasta db
> > >     into the pub
> > >     > > >> folder using filezilla, however, filezilla tells me that I
> > >     that there
> > >     > > >> is no adequate directory for the upload (see error
> message)??
> >
> > >     > > >> ..............
> > >     > > >> Command:        STOR
> > >     /pub/Hannes_20100301/20091125_AD_Boiani_oocyte_03.raw
> > >     > > >> Response:       550
> > >     /pub/Hannes_20100301/ipi.MOUSE.v3.64.fasta: No such
> > >     > > >> file
> > >     > > >> or directory
> > >     > > >> Command:        PASV
> > >     > > >> Response:       550
> > >     /pub/Hannes_20100301/20091125_AD_Boiani_oocyte_03.raw:
> > >     > > >> No such file or directory
> > >     > > >> Error:  Critical file transfer error
> > >     > > >> .............
> >
> > >     > > >> Kind regards,
> >
> > >     > > >> Hannes
> >
> > >     > > >> On 26 Feb., 19:18, Brian Pratt <[email protected]
> > >     <mailto:[email protected]>> wrote:
> > >     > > >> > Strange indeed.  If you can send me a minimum data set
> > >     that shows the
> > >     > > >> > problem I could take a look (presumably three files and
> > >     the fasta db).
> > >     > > >>  If
> > >     > > >> > they're too big to email, you can ftp toftp://
> > >     > > >> insilicos.serveftp.net/pub <
> http://insilicos.serveftp.net/pub>.
> > >     > > >> > Brian
> > >     > > >> > On Fri, Feb 26, 2010 at 7:10 AM, Hannes Drexler
> > >     > > >> > <[email protected]
> > >     <mailto:[email protected]>>wrote:
> >
> > >     > > >> > > Hi Brian,
> >
> > >     > > >> > > thought about it too, however, when I delete the first
> two
> > >     > > >> > > successfully handled files from the sequence and start
> > >     the database
> > >     > > >> > > search again with the next / third file of the list,
> > >     the subsequent
> > >     > > >> > > two files are also successfully sent through the
> > >     pipeline. I repeated
> > >     > > >> > > it a few more times now and to me it looks like as if
> > >     XTandem database
> > >     > > >> > > searches are currently only possible in tranches of
> > >     two. Strange,
> > >     > > >> > > isn�it?
> >
> > >     > > >> > > Hannes
> >
> > >     > > >> > > 2010/2/24 Brian Pratt <[email protected]
> > >     <mailto:[email protected]>>:
> > >     > > >> > > > You'll want to narrow it down to identify the problem
> > >     - for
> > >     > > >> example,
> > >     > > >> > > what
> > >     > > >> > > > happens when you omit that 3rd file?
> >
> > >     > > >> > > > On Wed, Feb 24, 2010 at 2:04 AM, hcadrexler <
> > >     > > >> [email protected] <mailto:[email protected]
> >>
> > >     > > >> > > > wrote:
> >
> > >     > > >> > > >> Hi there,
> >
> > >     > > >> > > >> I tried to perform an XTandem search following the
> > >     XTandem 2009
> > >     > > >> > > >> tutorial using my own data (29 mzXML files). The
> > >     Database search is
> > >     > > >> > > >> performed for the first two files in the sequence
> > >     without any
> > >     > > >> problems
> > >     > > >> > > >> but then stops and does not proceed any further with
> > >     the third (and
> > >     > > >> > > >> subsequent) files. I cannot figure out where the
> > >     mistake was made.
> > >     > > >> > > >> Does anybody know why this might happen?
> >
> > >     > > >> > > >> Kind regards,
> >
> > >     > > >> > > >> Hannes
> >
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