I installed the 4.0.7 binary version for RedHat in order to see whether I could use it for 'real work'. First, I think it is not easy to learn how to use OpenDX. To produce a simple line plot took me 1 hour. I finally gave up when I tried to import my own data in a manner which would make sense. Members of the 'research community' are often short of time and this might prevent them from using OpenDX. Second, a really severe problem are the very limited possibilities for data analysis. If one wants to EXPLORE the data interactively and not just wants to produce stylish pictures of the data, OpenDX might not be the right thing.
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