[ccp4bb] Postdoc position available at LNBR/CNPEM

[Mario Tyago Murakami]

Postdoctoral position available in carbohydrate enzymology and structural 
biology
We are looking for candidates who are interested in exploring the microbial 
dark matter from Brazilian mega biodiversity aiming at elucidating novel 
mechanisms involved in carbohydrate breakdown and modification using an 
interdisciplinary approach including integrated omics, carbohydrate enzymology, 
site-directed mutagenesis, X-ray crystallography, Cryo-EM, mass spectrometry 
and computational biology.
Application deadline June 21, 2024; Expected starting date August 1st, 2024.

Mário Murakami
mario.murak...@lnbr.cnpem.br



Mário T. Murakami

Scientific Director

Brazilian Biorenewables National Laboratory (LNBR)

National Center for Research in Energy and Materials (CNPEM)

Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, São Paulo, Brasil. CEP: 
13083-100

(19) 3518-3198 | (19) 99654 3909 | 
mario.murak...@lnbr.cnpem.br

www.lnbr.cnpem.br / 
www.cnpem.br




Aviso Legal: Esta mensagem e seus anexos podem conter informações confidenciais 
e/ou de uso restrito. Observe atentamente seu conteúdo e considere eventual 
consulta ao remetente antes de copiá-la, divulgá-la ou distribuí-la. Se você 
recebeu esta mensagem por engano, por favor avise o remetente e apague-a 
imediatamente.

Disclaimer: This email and its attachments may contain confidential and/or 
privileged information. Observe its content carefully and consider possible 
querying to the sender before copying, disclosing or distributing it. If you 
have received this email by mistake, please notify the sender and delete it 
immediately.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position Sweden

[Magnus Andersson]

Hi,

We’re looking for a postdoc at Umeå University to work on membrane protein 
structural biology with a variety of methods, such as cryo-EM and X-ray 
solution scattering. The project can be accommodated to fit the interests of 
the candidate.

This is a great opportunity to contribute to developing membrane protein 
structural biology within the Integrated Structural Biology community at Umeå 
University.

https://www.nature.com/naturecareers/job/12817729/postdoctoral-scholarship-2-years-within-regulation-of-membrane-protein-transport/

Best,

Magnus

###
Magnus Andersson, Associate Professor
Integrated Structural Biology
Department of Chemistry
Umeå University

Email: magnus.p.anders...@umu.se
Phone: +46 720 837370

Mailing address:
Umeå University
Department of Chemistry
KBC-building
SE-901 87 Umeå

Visiting address:
Linnaeusvägen 6





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position Structural Virology, BNITM & CSSB Hamburg

[Maria Rosenthal]

Moin!

I have a 2-year postdoc position to fill in the field of structural 
biology of protein-RNA complexes.


Location is beautiful Hamburg, Germany, with top-notch research 
facilities, great collaborators and a fun and motivated team.


Application deadline is May 19th.

More details here: 
https://jobs.bnitm.de/Postdoc-mfd-full-time-or-part-time-EG-13-TV-AVH-Structural-eng-j330.html


For any questions, feel free to send me an email.

Cheers,

Maria Rosenthal

--

Dr. Maria Rosenthal
Group Leader Structural Virology
Dept. of Virology

Bernhard Nocht Institute for Tropical Medicine
Bernhard-Nocht-Str. 74
D-20359 Hamburg
Germany
Phone:  +49 40 285380 930
Email:  rosent...@bnitm.de
Web:www.bnitm.de 
twitter.com/bnitm_de 
twitter.com/mariar0senthal 


*Join Bunyavirus2024 in Leeds, July 15-16 2024, 
https://eu.eventscloud.com/website/13030/home/*



Foundation under Public Law
Member of the Leibniz Association
Board of Directors: Prof. Dr. Jürgen May (Chair), Prof. Dr. Stephan 
Günther, Prof. Dr. Iris Bruchhaus, Birgit Müller (Managing Director)

Chair of the Board of Trustees: State Ministry Dr. Eva Gümbel



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position in Vancouver - cryo-EM analysis of bioelectricity complexes

[Filip Van Petegem]

Dear colleagues,

A postdoctoral position is available to work on the problem of coupling
between different ion channels in electrically excitable tissues.

https://www.vanpetegemlab.com/opportunities.html

The project entails cryo-EM, electrophysiology and protein biophysics, and
will make use of our state-of-the-art high-resolution EM facility (
https://cryoem.med.ubc.ca/), dedicated patch clamp and planar lipid bilayer
electrophysiology setups, as well as all tools to express and purify
proteins from bacterial and mammalian cells.

We foster a diverse and inclusive lab environment and are looking for
motivated lab members that share these values. Postdoctoral fellows receive
the opportunity to join the Biochemistry Postdoctoral Scholar program at
UBC.  Joining the lab also means joining our local community of labs and
clinicians interested in ion channels and their associated diseases.

We are looking for motivated individuals with a recent PhD (obtained within
the last 4 years) using either structural biology (crystallography, NMR, or
cryo-EM) or electrophysiology. All applications can be sent to
filip.vanpetegem'at'ubc.caPlease include an updated CV, names and
contact details for 3 references, and describe your motivation to join the
team. This is an excellent opportunity for structural biologists to learn
complementary methods, or for electrophysiologists to get exposed to
structural biology methods.


Filip Van Petegem



-- 
Filip Van Petegem, PhD
Professor, Dept. of Biochemistry and Molecular Biology
The University of British Columbia
2350 Health Sciences Mall - Rm 2.356
Vancouver, V6T 1Z3

phone: +1 604 827 4267
email: filip.vanpete...@gmail.com
Twitter: @FilipPetegem
Bluesky: @filipvanpetegem

website: https:///www.vanpetegemlab.com



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position in Structural and Functional Studies of Transmembrane Transporters @ Paz lab, HWI

[Aviv Paz]

The Paz lab at the Hauptman-Woodward Medical Research Institute (HWI) is 
seeking a highly motivated and talented postdoctoral researcher to study the 
function and structure of transport proteins. The position is fully funded, 
available immediately, and is based in Buffalo, NY. The successful candidate 
will contribute to a project aimed at elucidating the structural basis 
controlling the functions of medically relevant transporters using 
cryo-electron microscopy (cryo-EM) and/or X-ray crystallography and various 
biochemical, biophysical, and functional tools. The candidate will also be 
responsible for interpreting and modeling the functional results and structures.

We offer a stimulating and collaborative research environment with access to 
state-of-the-art facilities that enable extensive structure/function studies 
such as the National High-Throughput Crystallization Center and our 
Cryo-Electron Microscopy Center. The candidate is expected to work 
independently, keep meticulous records, and will have the opportunity to 
present their research at national and international conferences and to 
interact with scientists from a variety of disciplines.

Requirements:

•   A Ph.D. in structural biology, biochemistry, biophysics, or a related 
field.
•   Extensive experience and understanding of molecular biology, protein 
production, purification, biochemistry, and structural determination.
•   A proven record of scientific productivity, demonstrated by 
high-quality publications in peer-reviewed journals.
•   Excellent communication and teamwork skills.

HWI is a prominent independent center for structural biology research, with 
outstanding facilities, also managing the IMCA-CAT beamline 17-ID at the 
Advanced Photon Source at Argonne National Laboratory in Lemont, IL. The 
Institute has strong ties with its neighbors at the Jacobs School of Medicine 
at University at Buffalo and Roswell Park Comprehensive Cancer Center.

Application review will begin immediately, and the position will remain open 
until filled. The compensation level for this full-time position is $56,484 and 
includes a generous benefits package. To apply, please send a cover letter, a 
CV, and contact information for three references to a...@hwi.buffalo.edu.

HWI is an equal-opportunity employer and is committed to creating a diverse and 
inclusive environment for all employees.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in the XFEL Hub at Diamond Light Source

[Orville, Allen (DLSLtd,RAL,LSCI)]

Hi,

The XFEL Hub at Diamond Light Source in Oxfordshire UK, has a Postdoctoral 
Research Associate position open (three years duration) to address 
time-resolved, dynamic structural biology. We are eager to work with you on 
serial crystallography correlated with X-ray emission spectroscopy with 
applications and data collected at Diamond and at XFELs, including SwissFEL.

More information and the application process are in the link below.
https://vacancies.diamond.ac.uk/vacancy/postdoctoral-research-associate-xfel-hub-552310.html

The initial closing date for applications is 02 April 2024, however 
applications will be reviewed and interviewed on an ongoing basis until this 
vacancy is filled.

AMO
~ ~ ~ ~ ~
Allen M. Orville, Ph.D.
Wellcome Investigator
Principal Scientist, XFEL Hub at Diamond Light Source
Harwell Science and Innovation Campus
Didcot, Oxfordshire
OX11 0DE
United Kingdom

Phone: +44 (0) 1235 567505
Mobile: +44 (0) 7471 026061
email: allen.orvi...@diamond.ac.uk

AMO site: https://www.diamond.ac.uk/Instruments/Mx/XFEL-Hub/Staff/Orville.html
XFEL-Hub site: https://www.diamond.ac.uk/Instruments/Mx/XFEL-Hub.html






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position available

[Gabriel Demo]

Dear all,

We seek a talented individual to fill a postdoctoral position (at the Central 
European Institute of Technology (CEITEC), Masaryk University Brno, Czech 
Republic.) with expertise in the field of cryo-electron microscopy and 
translation regulation. Ideal candidates should possess a solid foundation in 
biochemistry or structural biology, particularly in single-particle 
cryo-electron microscopy or protein crystallography.

For more details, please visit our website 
https://demolab.ceitec.cz/
 and the postdoctoral position offer 
https://www.ceitec.eu/postdoctoral-fellow-in-the-research-group-of-gabriel-demo/j500.

To apply, please submit your CV, along with contact information for three 
referees, and a brief motivational letter to recruitm...@ceitec.muni.cz. The 
deadline for applications is June 30th, 2024.

Best regards,

--



Mgr. Gabriel Demo, PhD. | CEITEC MU

Junior Group Leader



tel: +420 549 49 7827

e-mail: gabriel.d...@ceitec.muni.cz

web: www.ceitec.cz



Masarykova univerzita

Central European Institute of Technology

Kamenice 5, 625 00 Brno

Kancelář A35/1S155



#CEITECScience

facebook
 | 
twitter
 | 
instagram
 | 
linkedin
 | 
youtube



[E6CD5E50]




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position membrane protein cryo-EM

[Magnus Andersson]

A postdoctoral position is available at the Andersson lab, Umeå University, 
Sweden.

We focus on membrane protein structural biology to understand heart disease and 
antimicrobial resistance. This project is based on cryo-EM characterization – 
but we also use time-resolved X-ray solution scattering and MD simulations 
within the group. We have several ongoing projects and membrane protein 
production protocols are in place also for nanodisc insertion. The focus will 
be structural characterization by cryo-EM and development of time-resolved 
cryo-EM.

Apply here: 
https://www.umu.se/en/work-with-us/postdoctoral-scholarships/6-140-24/

Application deadline February 28.

Best,

Magnus



###
Magnus Andersson, Associate Professor
Integrated Structural Biology
Department of Chemistry
Umeå University

Email: magnus.p.anders...@umu.se
Phone: +46 720 837370

Mailing address:
Umeå University
Department of Chemistry
KBC-building
SE-901 87 Umeå

Visiting address:
Linnaeusvägen 6




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

Re: [ccp4bb] Postdoc Position at the Department of Biochemistry and Redox Biology Center, the University of Nebraska-Lincoln

[limei zhang]

Dear all,
Our group has openings for two postdoc positions. Please see the details below.
Thanks for your time!
Limei Zhang
Associate Professor
Department of Biochemistry/Redox Biology Center
University of Nebraska-Lincoln
Email: limei.zh...@unl.edu
http://biochem.unl.edu/limei-zhang


Postdoctoral Positions at the Department of Biochemistry and Redox Biology 
Center

University of Nebraska-Lincoln, Lincoln NE, USA

Two postdoc positions are available in Dr. Limei Zhang’s group at the 
Department of Biochemistry and Redox Biology Center, University of 
Nebraska-Lincoln, for highly motivated candidates who are interested in 
structural biology, redox biology and infectious disease. The position will 
offer a competitive salary and benefits.

Zhang Group: With funding support from both NIH and NSF, the Zhang Group 
applies a suite of interdisciplinary tools to investigate the 
structure-mechanism relationships of metalloproteins in redox reactions, stress 
responses and antibiotic resistance. For more information about the Zhang 
Group, please visit the website: https://biochem.unl.edu/limei-zhang.

Job responsibilities: The postdoctoral fellow is expected to independently 
design and conduct high-quality research experiments for the assigned project 
under the supervisor’s guidance; analyze data and draft manuscripts for 
publication; take roles in the lab maintenance with other group members; and 
assist the supervisor to mentor undergraduate and graduate students.

Qualifications: The required qualifications include a recent Ph.D. degree (or 
expected soon) in biochemistry, biophysics, chemistry, microbiology or a 
related field; a strong record in conducting high-quality research in protein 
biochemistry or biophysics. Experience in either structural biology (X-ray 
crystallography, cryo-EM or nuclear magnetic resonance) or molecular biology of 
transcriptional regulation is highly desirable.

Training: The postdoc fellow will have the opportunity to learn comprehensive 
methods in preparation and characterization of metalloproteins in the Zhang 
group and first-hand training in cryo-EM in the collaborating research center 
supported by the NSF EPSCoR Research Fellowship.

The University of Nebraska-Lincoln is located in a vibrant and safe city 
offering an outstanding and affordable quality of life, and numerous 
multi-cultural and entertainment benefits. The Redox Biology Center is 
organized as a broad-based interdisciplinary and multi-institutional entity 
involving researchers from the University of Nebraska-Lincoln and the 
University of Nebraska Medical Center in Omaha, and offers a supportive and 
collaborative international environment as well as access to cutting-edge 
proteomics, metabolomics, crystallography, and NMR facilities. We are also 
expected to have a cryo-EM instrument (Glacios w/Falcon 4i, Selectris EF & 
Ceta-D camera) installed at UNL in the summer of 2023.

Recognizing that diversity within a context of inclusivity enhances creativity, 
innovation, impact, and a sense of belonging, the Institute of Agriculture and 
Natural Resources (IANR) and the Department of Biochemistry are committed to 
creating learning, research, Extension programming, and work environments that 
are inclusive of all forms of human diversity. We actively encourage 
applications from and nominations of individuals from underrepresented groups.

To apply for the position, please submit a letter of interest with a short 
summary of past research experience; your curriculum vitae, and contact 
information for three professional references, including phone numbers and 
emails to limei.zh...@unl.edu

As an EO/AA employer, qualified applicants are considered for employment 
without regard to race, color, ethnicity, national origin, sex, pregnancy, 
sexual orientation, gender identity, religion, disability, age, genetic 
information, veteran status, marital status, and/or political affiliation. See 
http://www.unl.edu/equity/notice-nondiscrimination.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position available

[Wei Zhang]

Dear all,

A NIH-funded postdoctoral research associate position is available at Dr.
Wei Zhang's laboratory at the University of Minnesota (Minneapolis,
Minnesota, USA). The successful candidate will study enveloped
virus assembly and entry using cryo-EM, single particle reconstruction,
cryo-ET, subtomogram averaging, and related biochemical and biophysical
methods. The position offers opportunities to work with outstanding
researchers through established and successful collaborations.



*Required Qualifications*. Candidates should have: (1) a Ph.D. in virology,
structural biology, biophysics, or related field; (2) published in
international peer-reviewed journals.



*Preferred Qualifications*. Experience protein structure determination and
strong computation skills.



We welcome all applicants who have a passion for research and the drive to
learn and contribute to the field.  Interested candidates should submit a
pdf with cover letter, CV and names/info for three references to Dr. Zhang
at zhang...@umn.edu.


Best regards,


Wei Zhang



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position available

[Birte Hoecker]

Dear all,

sorry to all who are not currently looking for a PostDoc position.


Postdoctoral opportunity – Structural Biology / Protein Engineering

An ERC-funded postdoctoral position is available in the lab of Birte Höcker at 
Bayreuth University, Germany. Within the project we apply structural biology, 
protein engineering and computational protein design to construct new protein 
motors. We are seeking a motivated personality with experience in protein 
biochemistry and structural biology interested in working in an 
interdisciplinary and international team. The position requires a PhD in 
biochemistry, biotechnology, structural biology, or a related field. Experience 
with structure determination, enzymology, computational protein design or 
directed evolution are all welcome.

The overall project is in collaboration with partners from Lund University, 
Sweden and UNSW in Sydney, Australia. Our own group is situated in the 
biochemistry department of the University of Bayreuth. The department is 
well-equipped in terms of structural biology, biophysics, and computing. 
Bayreuth is a beautiful city in the north of Bavaria in between Fränkischer 
Schweiz and the Fichtelgebirge with great outdoor opportunities. Interested 
candidates should contact me directly for more details on the project. A full 
application should include a CV, short description of prior experience, 
motivation and contact details of references.

Birte Höcker (birte.hoec...@uni-bayreuth.de 
) 




Birte Höcker, Prof. Dr. 
Biochemie, NWIII
Universität Bayreuth
95440 Bayreuth, Germany
www.proteindesign.uni-bayreuth.de






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in structural biology of membrane proteins at the University of Pavia

[Francesca Magnani]

Dear CCP4BB,

We're offering a 2-year position (with possible extensions depending on funding 
availability). The project is focused on exploring solute carrier transporter 
mechanisms through a multidisciplinary approach combining biochemistry, cell 
biology and structural biology. Our lab, part of the University of Pavia's 
Department of Biology and Biotechnology, provides access to cutting-edge 
resources for protein production and biophysical characterisation. Additional 
state-of-the-art instruments are available though a core facility 
(https://cgs.unipv.it/eng/), ensuring an excellent research environment. All 
this is in the cute city of Pavia, just a 20-minute train ride from Milan.

Interested applicants should apply BEFORE 6th of NOVEMBER through the following 
link: 
https://pica.cineca.it/unipv 
where the project is identified as dbb-2023-b08 (responsible person: Francesca 
Magnani).

For additional information, please do not hesitate to contact me at:
francesca.magn...@unipv.it

Best regards,
Francesca

Francesca Magnani, PhD
University of Pavia
Dept. of Biology and Biotechnology
Via Ferrata, 9
27100 Pavia
ITALY

Assistant professor in Molecular Biology at DBB-UNIPV
https://www.fmagnani-lab.com



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in structural biology of membrane proteins at the University of Pavia

[Francesca Magnani]

Dear CCP4BB,


We're offering a 2-year position (with possible extensions depending on
funding availability). The project is focused on exploring solute carrier
transporter mechanisms through a multidisciplinary approach combining
biochemistry, cell biology and structural biology. Our lab, part of the
University of Pavia's Department of Biology and Biotechnology, provides
access to cutting-edge resources for protein production and biophysical
characterisation. Additional state-of-the-art instruments are available
though a core facility (https://cgs.unipv.it/eng/), ensuring an excellent
research environment.


Interested applicants should apply before the *6th of November* through the
following link: https://pica.cineca.it/unipv where the project is
identified as dbb-2023-b08 
(responsible person: Francesca Magnani).


For additional information, please do not hesitate to contact me at
francesca.magn...@unipv.it


Best regards,


--
Francesca Magnani, PhD
University of Pavia
Dept. of Biology and Biotechnology
Via Ferrata, 9
27100 Pavia
ITALY

Ph: (+39) 0382-98-5547
Lab website 

*Assistant professor in Molecular Biology at **DBB-UNIPV*




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position

[Magnus Andersson]

Hi,

We have an open postdoc position focused on data-driven structural refinement 
of neutron reflectometry (and SAXS) data to understand processes at biological 
membranes. The position is shared in the research teams of Magnus Andersson and 
Gerhard Gröbner, Umeå University, Sweden – as part of the "Excellence by 
Choice" Postdoctoral Programme in Life Science (Patron Nobel laureate 
Emmanuelle Charpentier). More information about the programme here:

https://www.nature.com/articles/d42473-023-00296-1

And apply (project no. 10) here:

https://www.umu.se/en/ucmr/ec-postdoc-programme/excellence-by-choice-postdoctoral-programme-in-life-science/

Do not hesitate to contact Magnus Andersson  
(magnus.p.anders...@umu.se) or Gerhard 
Gröbner (gerhard.grob...@umu.se).

Best wishes,

Magnus & Gerhard



###
Magnus Andersson, Associate Professor
Integrated Structural Biology
Department of Chemistry
Umeå University

Email: magnus.p.anders...@umu.se
Phone: +46 720 837370

Mailing address:
Umeå University
Department of Chemistry
KBC-building
SE-901 87 Umeå

Visiting address:
Linnaeusvägen 6




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in structural enzymology in Cambridge, UK

[Stephen Graham]

Hi all,

We have an exciting opportunity for a postdoctoral research scientist to study 
the physical properties of viral enzymes that allow them to evolve resistance 
to anti-viral drugs. This project will use advanced computation biology 
approaches, enzymology and structural biology to define structurally invariant 
regions of the SARS-CoV-2 MPro protease. This will inform the design of future 
therapies that reduce/prevent the evolution of drug resistance and may 
illuminate how evolution of resistance mutations will affect the potency of 
MPro drugs already in clinical trials. This project is a collaboration between 
the University of Cambridge (UK) and Rhodes University (South Africa), funded 
by the Novo Nordisk Foundation as part of the Pandemic Antiviral Discovery 
(PAD) initiative (see 
https://padinitiative.com/awarded-grants/rhodes-university-ozlem-tastan-bishop/).

The successful candidate will be based in my lab within the Virology Division, 
Department of Pathology, on the Cambridge Biomedical Campus - Europe's largest 
biomedical research centre. Cambridge is a great place to work: we have access 
to shiny instruments for modern biophysical and structural research, we have 
regular data collection time at Diamond Light Source, there are lots of smart 
people who you can talk science with, there are old buildings where you can 
dress up in funny gowns to have dinner in wood-panelled rooms, and it's small 
enough that you can either walk or cycle to most places you need to be. There's 
even a river running through it with cows grazing on the banks. If you are a 
biochemists/enzymologist/structural biologist who wants to work with an 
international multidisciplinary team to address fundamental research questions 
with direct relevance to human health and pandemic preparedness, we want to 
hear from you!

Full details of the post and how to apply can be found at 
https://www.jobs.cam.ac.uk/job/42708/. Please note that you must apply through 
the website - applications emailed to me can't be considered but I am happy to 
answer any specific questions you might have.

Cheers,

Stephen

--
Prof. Stephen Graham
School of Biological Sciences Theme Leader: Infection and Immunity
Department of Pathology
University of Cambridge
Tennis Court Road
Cambridge CB2 1QP
http://www.atomicvirology.path.cam.ac.uk/




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position in protein design - industry/academia collaboration in Vancouver

[Filip Van Petegem]

*Postdoctoral opportunity in Protein Design and Structural Biology*


A postdoctoral position is available in the laboratory of Prof. Filip Van
Petegem at the University of British Columbia.  The goal is to apply state
of the art computational protein design methods to create novel protein
molecules to enable structural cryo-EM characterization of therapeutic
candidates and their target. The project is a collaboration with Amgen, one
of the world’s leading biotechnology companies, and is supported through a
MITACS scholarship.



In recent years, antibody-based medicines have emerged as one of the most
effective modalities to treat diverse illnesses from cancer and
inflammation to metabolic and neurological disorders. The successful
candidate will work with experts in computational design to create novel
scaffold proteins and will gain hands-on experience in evaluating
protein-protein interactions in an industrial setting.



The individual we seek has a background in computational protein design and
an interest in testing their designs in a laboratory setting.  We are
looking for a talented and highly motivated PhD graduate with a proven
track record in biochemistry, bioengineering, computer sciences or a
related discipline and a desire to push the envelope of biotherapeutic
research. Experience in protein structure visualization (i.e. PyMOL) and
design tools (i.e. Rosetta) is desired along with experience with protein
purification and experimental characterization. This position offers a
unique opportunity in early-stage drug discovery at the interface of
academia and industry.

Please email your statement of interest and CV to:



Prof. Filip Van Petegem

The University of British Columbia

filip.vanpete...@gmail.com



Dr. Christy A. Thomson

Amgen British Columbia

cthom...@amgen.com





-- 
Filip Van Petegem, PhD
Professor, Dept. of Biochemistry and Molecular Biology
The University of British Columbia
2350 Health Sciences Mall - Rm 2.356
Vancouver, V6T 1Z3

phone: +1 604 827 4267
email: filip.vanpete...@gmail.com
http://crg.ubc.ca/VanPetegem/

Twitter: @FilipPetegem



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in biochemistry and TEM, AFMB lab, Marseille, France

[MARCHOT Pascale]

Postdoc position in biochemistry and TEM, AFMB lab, Marseille, France


A full-time, 24-30 months post-doctoral position for a "structural biochemist" 
with expertise in TEM is available in team “Structural Glycobiology and 
Neurobiology” of the “Architecture et Fonction des Macromolécules Biologiques 
(AFMB)” laboratory, Marseille, France. The AFMB lab is about to welcome a 
state-of-art Glacios 2 TEM 200kV equipped with Selectris X EF and Falcon 4i 
camera that will be used for the project.

The main scope of the project is to document the binding site, orientation and 
mode of action of new peptidic effectors of a ligand-gated ionic channel, using 
TEM and complementary biochemical and biophysical methods.

Reliable experience in expression/purification/biophysical characterization of 
soluble/membrane proteins and their complexes and in electron microscopy is 
mandatory.

The position opens on November 01, 2023, and will remain open until filled.

Details of the offer and the application procedure are available at
https://www.afmb.univ-mrs.fr/en/call-for-applications-for-a-postdoctorate-fellow-in-structural-biochemistry/
or

https://emploi.cnrs.fr/Offres/CDD/UMR7257-PASMAR-002/Default.aspx?lang=EN


Looking forward to receiving your application!






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position, University of Oxford

[Anthony Roberts]

Dear All,

A post-doctoral position is available in our laboratory at the University of 
Oxford to investigate how membrane proteins are transported into cilia. See 
PMID 36462505 (Cell 2022) for background. Further details about this position 
are available in the link below:
https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10_internal_external=E_display_in_irish=N_process_type=_applicant_no=_form_profile_detail=_display_apply_ind=Y_refresh_search=Y_recruitment_id=167632

The successful candidate will have access to outstanding facilities for 
structural and cell biology research, including instruments for cryo-EM, 
cryo-ET and FIB milling:
http://web.path.ox.ac.uk/~bioimaging/electronmicroscope/cryo_em.html

Please get in touch directly 
(anthony.robe...@path.ox.ac.uk) for 
informal inquiries. The closing date for applications is 25th Sep 2023.

Best wishes,

Anthony



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in structural cell biology at the MRC Laboratory of Molecular Biology, Cambridge UK

[Jan Löwe]

*We are recruiting a postdoctoral researcher to investigate the 
molecular mechanisms of bacterial cell division through **/in 
situ/**structural biology.*


The goal of the project is to reveal the organisation and structure of 
the FtsZ filaments and divisome complexes that drive cell constriction 
through focussed ion beam (FIB) milling and electron cryotomography 
(cryo-ET) of Gram-positive bacteria.


The new 3-year position will be located at the MRC Laboratory of 
Molecular Biology (LMB) in Cambridge, UK within the group of Jan Löwe, 
working in collaboration with the groups of Séamus Holden (Warwick 
University, UK) and Anđela Šarić (Institute of Science and Technology 
Austria).


You will be an enthusiastic individual with a PhD in a relevant field, 
or due to complete within 6 months, with a strong background in 
structural biology.


Experience in cryo-EM is required. Some previous work using tomography 
and/or FIB milling will be helpful.


More details and on how to apply are here: 
https://www.nature.com/naturecareers/job/12803194/postdoctoral-scientist-structural-studies-dr-jan-loewe-lmb-2203/


Jan Löwe

MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
Email: j...@mrc-lmb.cam.ac.uk
Phone +44 1223 26 7644
Website: http://www2.mrc-lmb.cam.ac.uk/groups/jyl//




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at SBBS, QMUL

[Vidya Darbari]

A Postdoctoral Research Assistant position in Structural Biology is available 
at Queen Mary University of London (QMUL) to work with Professor Richard 
Pickersgill. This project is in collaboration with Professor Martin Warren and 
colleagues at the Quadram Institute,  also in collaboration with Dr Arianna 
Fornili (QMUL) on the computational aspects of the work. The post-holder will 
be funded by BBSRC on a project entitled “Vitamin scavenging in the gut: 
Structure/function of the tight-binding B12 foraging machinery in Bacteroides – 
and its biotechnological applications”.

The successful candidate should have a PhD (or close to completion) in 
structural biology, biophysics, biochemistry, or a related field. The candidate 
should be able to provide evidence of expertise in protein purification, 
structural biology, and preferably X-ray crystallography. Excellent computing 
skills and a track record of high-quality published research would be an 
advantage. Self-motivation, an ability to work as part of a team and excellent 
research management and presentation skills are essential.

The start date is July 2023 or as soon as possible thereafter. The post is 
full-time and available for 2 years. The salary is in the range of £36,411 - 
£43,592 per annum and is inclusive of London allowance.

Informal enquiries should be addressed to Prof Richard Pickersgill via 
r.w.pickersg...@qmul.ac.uk

The closing date for applications is 14th June 2023.

Further details on the post and application process can be accessed using the 
link:  https://www.jobs.ac.uk/job/CZW464/postdoctoral-research-assistant

Best Regards,
Vidya



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position at the Department of Biochemistry and Redox Biology Center, the University of Nebraska-Lincoln

[limei zhang]

Dear all,
Our group has an opening for several research opportunities. Please see the 
details below.
Thanks for your time!
Limei Zhang
Associate Professor
Department of Biochemistry/Redox Biology Center
University of Nebraska-Lincoln
Email: limei.zh...@unl.edu
http://biochem.unl.edu/limei-zhang


Postdoctoral Position at the Department of Biochemistry and Redox Biology Center

University of Nebraska-Lincoln, Lincoln NE, USA

We are looking for a highly motivated postdoc to work on the structural and 
mechanistic understanding of iron-sulfur proteins involved in redox sensing, 
stress response and antibiotic resistance in Dr. Limei Zhang’s group at the 
Department of Biochemistry and Redox Biology Center, University of 
Nebraska-Lincoln. The position will offer a competitive salary and benefits.

Zhang Group: With funding support from both NIH and NSF, the Zhang Group 
combines state-of-the-art structural biology approaches including cryo-EM, and 
X-ray crystallography with biochemical, biophysical, and molecular biological 
methods to investigate novel metalloproteins involved in redox reactions and 
infectious diseases. For more information about the Zhang Group, please visit 
the website: https://biochem.unl.edu/limei-zhang.

Job responsibilities: The postdoctoral fellow is expected to independently 
design and conduct high-quality research experiments for the assigned project 
under the supervisor’s guidance; analyze data and draft manuscripts for 
publication; take roles in the lab maintenance with other group members; and 
assist the supervisor to mentor undergraduate and graduate students.

Qualifications: The required qualifications include a recent Ph.D. degree (or 
expected soon) in biochemistry, biophysics, chemistry, microbiology or a 
related field; a strong record in conducting high-quality research in 
structural biology or molecular biology. Experience in transcriptional 
regulation, biomolecular interaction, or structural biology (X-ray 
crystallography or cryo-EM) is highly desirable.

Training: The postdoc fellow will have the opportunity to learn comprehensive 
methods in preparation and characterization of metalloproteins in the Zhang 
group and first-hand training in cryo-EM in the collaborating research center 
supported by the NSF EPSCoR Research Fellowship.

Environment: The University of Nebraska-Lincoln is located in a vibrant and 
safe city offering an outstanding and affordable quality of life, and numerous 
multi-cultural and entertainment benefits. The Redox Biology Center is 
organized as a broad-based interdisciplinary and multi-institutional entity 
involving researchers from the University of Nebraska-Lincoln and the 
University of Nebraska Medical Center in Omaha and offers a supportive and 
collaborative international environment as well as access to cutting-edge 
proteomics, metabolomics, crystallography, and NMR facilities. We are also 
expected to have a cryo-EM instrument (Glacios w/Falcon 4i, Selectris EF & 
Ceta-D camera) installed at UNL in 2023.

Recognizing that diversity within a context of inclusivity enhances creativity, 
innovation, impact, and a sense of belonging, the Institute of Agriculture and 
Natural Resources (IANR) and the Department of Biochemistry are committed to 
creating learning, research, Extension programming, and work environments that 
are inclusive of all forms of human diversity. We actively encourage 
applications from and nominations of individuals from underrepresented groups.

How to Apply: To apply for the position, please submit a letter of interest 
with a short summary of past research experience; your curriculum vitae, and 
contact information for three professional references, including phone numbers 
and emails to limei.zh...@unl.edu

As an EO/AA employer, qualified applicants are considered for employment 
without regard to race, color, ethnicity, national origin, sex, pregnancy, 
sexual orientation, gender identity, religion, disability, age, genetic 
information, veteran status, marital status, and/or political affiliation. See 
http://www.unl.edu/equity/notice-nondiscrimination.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in San Antonio, TX

[Yogesh Gupta]

*NIH-funded Postdoctoral Associate position in Structural Virology at the
University of Texas Health Science Center, San Antonio*

The laboratory of Dr. Yogesh Gupta (http://ccri.uthscsa.edu/YGupta.html) is
seeking an enthusiastic Postdoctoral Associate to study the structures and
specificity of RNA modification enzymes. We will mainly use X-ray
crystallography and cryo-EM to study the mechanisms and develop small
molecule antiviral candidates. We provide a rich multi-disciplinary
environment and access to cutting-edge technologies to our trainees.



Further details of our recent work can be found here:

Elife. 2022 Jan 21;11:e67150. doi: 10.7554/eLife.67150
.

Nature Communications. 2021 Jun 2; 12: 3287. PMID: 34078893. doi:
10.1038/s41467-021-23594-y


Nature Communications. 2020 Jul 24;11(1):3718. PMID: 32709886. doi:
10.1038/s41467-020-17496-8




Preference will be given to applicants with demonstrated experience in
protein purification from insect or mammalian cells, protein/nucleic acid
biochemistry, X-ray crystallography, and cryo-EM. Candidates are expected
to possess strong organizational and interpersonal skills and the ability
to work independently but also effectively and collaboratively as part of a
team. An ideal candidate should hold (or soon expect to) a Ph.D. or
equivalent degree in biochemistry/biophysics/structural biology.



The Greehey Children’s Cancer Research Institute (GCCRI) is a unique,
specialized cancer research center of UT Health Science Center San Antonio,
focusing on basic and translational research. It occupies a
state-of-the-art 100,000 sq. foot research facility on the university’s
Greehey Academic and Research Campus. The GCCRI has significant external
funding, a large endowment from the state, and links to philanthropic
entities. San Antonio is the nation’s seventh-largest city and is located
at the edge of the beautiful Texas Hill Country. San Antonio offers a rich,
multicultural community, affordable cost of living, excellent weather, and
a thriving biomedical industry. There is no state income tax in Texas.
Salary is competitive and commensurate with experience.



Interested candidates can apply by sending a short description of their
research accomplishments and a CV with the contact information of 3
references to Dr. Yogesh Gupta (email: gup...@uthscsa.edu).



*All Postdoctoral appointments are designated as security-sensitive
positions. UT Health San Antonio is an Equal Opportunity/Affirmative Action
Employer, including protected veterans and persons with disabilities.*


-- 
Yogesh Gupta, Ph.D.
Associate Professor
Department of Biochemistry and Structural Biology
University of Texas Health Science Center at San Antonio
8403 Floyd Curl Drive, San Antonio, TX, USA 78229
http://ccri.uthscsa.edu/YGupta.html



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position in time-resolved crystallography

[Schulz, Eike-Christian]

Dear all,

There is an opening for a PostDoc position in my group. Funding is generously 
provided by an ERC Synergy Grant for the DynaPLIX project, wherein we aim to 
understand the dynamics of protein ligand interaction via an integrative 
approach combining NMR-spectroscopy (Mikael Akke, Lund University, 
MD-simulations (Kresten Lindorff-Larssen, University of Copenhagen) and 
time-resolved crystallography (Eike C. Schulz, UKE Hamburg).

https://cordis.europa.eu/project/id/101071843

Directly located on the DESY Campus (Petra-III synchrotron/EU-XFEL), we will be 
making ample use of our recently developed HARE and LAMA methods but also 
explore the foundations of protein function via multi-dimensional 
crystallography. Further pushing technology and method development in the field 
I am also terribly excited about our most recent toy, the spitrobot - a 
crystal-plunger that enables cryo-trapping with a time-resolution in the ms 
domain.

Candidates interested in a PostDoc position, motivated to push the boundaries 
in time-resolved (serial) crystallography should reach out directly to me 
(ec.sch...@uke.de), exciting projects are ahead.

Recent pre-prints:
The spitrobot: https://www.biorxiv.org/content/10.1101/2022.09.20.508674v1
Multi-dimensional crystallography: 
https://www.biorxiv.org/content/10.1101/2021.11.07.467596v2

Recent publications:
SSX vs SFX (Science Advances 2021): 
https://www.science.org/doi/10.1126/sciadv.abf1380
Allosteric communication (Science 2019): 
https://www.science.org/doi/10.1126/science.aaw9904
LAMA (Nature Methods 2019) https://www.nature.com/articles/s41592-019-0553-1
HARE (Nature Methods 2018) https://www.nature.com/articles/s41592-018-0180-2


With best regards,

Eike




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position – University of Copenhagen

[Azadeh Shahsavar]

Dear all,



A Postdoc position is available in my group to to help provide a
fundamental understanding of glutamine transport mechanisms mediated by

human lysosomal sodium-coupled neutral amino acid transporters in health
and disease.



I am looking for a talented ambitious candidate, interested in structural
biology and transport mechanisms:



https://candidate.hr-manager.net/ApplicationInit.aspx/?cid=1307=19218=158818=5=false



Deadline: 16-April-2023



Please do not hesitate to contact me "a...@sund.ku.dk" if you have any
questions.



Kind regards,

Azadeh

-- 

*Azadeh Shahsavar, PhD*



*University of Copenhagen*

Faculty of Health and Medical Sciences

Department of Drug Design and Pharmacology

Jagtvej 162

DK-2100 Copenhagen



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position for noncoding RNAs-protein complexes

[Nakanishi, Kotaro]

The Nakanishi lab at The Ohio State University 
(https://u.osu.edu/nakanishilab/) is looking for a highly motivated and skilled 
postdoc.  Our group aims to understand how noncoding RNAs work with their 
cognate proteins to regulate gene expression.  We study human macromolecules 
involved in critical cellular events in normal conditions and diseases.  The 
successful candidates must have a Ph.D. and expertise in X-ray crystallography. 
 Practical skills (protein production on a large scale, protein purification 
using FPLC, crystallization, data collection, and structure determination) are 
essential.  Experience in Cryo-EM is advantageous.  For more information, 
please visit our website.

The position is available immediately.  The annual salary wage is $48,000 - 
60,000 for three years (renewable).  The weather in Columbus is stable, and the 
living cost is reasonable.  So, postdocs can focus on their research to build a 
successful career.

Interested candidates should send the following directly to nakanish...@osu.edu.
• CV including a publication list.
• One-page research statement including 1. the current work, 2. the reason for 
joining our
group, and 3. the future goals after postdoc training.
• Contact information of three references.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in QMUL London

[Aravindan Ilangovan]

Dear All

I am reposting this job advert. Deadline to apply is the 19th February.

We are looking for two postdocs with expertise in structural biology to join 
our research group in the Centre for Structural Biology at Queen Mary 
University of London. These Wellcome Trust funded posts will work towards 
understanding the molecular mechanism of DNA replication initiation in 
bacteria. This structural biology project will take advantage of the expertise 
in the lab working with nucleoprotein complexes aided by dedicated cryo-EM and 
X-ray crystallography facilities. The group has routine access to the Titan 
Krios microscopes at LonCEM and eBIC and an in-house computing infrastructure 
for data processing.

Details about the position and a link to the application system can be found 
here https://www.qmul.ac.uk/jobs/vacancies/items/7930.html

Feel free to contact me (a.ilango...@qmul.ac.uk) 
if you have any specific queries about these posts.

Best
Aravindan Ilangovan
Lecturer in Structural Biology
Abernethy Building,
QMUL London,
UK
https://www.ilangovan-lab.com/




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position available: Structural Biology of RNA-protein complexes

[Yunsun Nam]

A postdoctoral research position is available in the laboratory of Yunsun Nam 
Ph.D., in the Department of Biochemistry at the University of Texas 
Southwestern Medical Center, to study the mechanisms underlying RNA-protein 
complexes important for gene regulation. Our laboratory works on exciting 
projects dissecting how chemistry and structure contribute to assembling 
specific RNA-protein complex architectures important for normal gene 
expression, using structural biology and biochemistry. The RNA-protein 
complexes we study are relevant for normal development as well as diseases. As 
we unravel how dysregulated RNA-protein complexes derail gene expression and 
cause cancer, we use our mechanistic insights to identify novel therapeutic 
avenues.

Postdoctoral scholars will have opportunities to learn the newest methods in 
protein and nucleic acid biochemistry and biophysics, in addition to working in 
an exciting, fast-evolving field in biomedical sciences. We use various 
approaches, including cryo-electron microscopy (cryo-EM), X-ray 
crystallography, NMR spectroscopy, molecular biology, nucleic acid and protein 
biochemistry, genomics with next-generation sequencing, high-throughput 
screening for drug discovery, and cancer cell biology. The postdoctoral fellow 
will have ready access to the top-of-the-line equipment and resources necessary 
for the above approaches. For cryo-EM, we have ready access to four microscopes 
on our campus: two Titan Krios, one Glacios, and one Talos Arctica. Information 
on our postdoctoral training program, benefits, and a virtual tour can be found 
at http://www.utsouthwestern.edu/postdocs.

Candidates must hold a Ph.D. and/or M.D. degree. Experience in biochemistry and 
structural biology leading to publication in peer-reviewed journals is 
recommended. Interested individuals should send a CV, a statement of interest, 
and a list of three references as a single pdf file to: 
yunsun@utsouthwestern.edu (Lab Website: www.ynamlab.org).

UT Southwestern Medical Center is committed to an educational and working 
environment that provides equal opportunity to all members of the University 
community.  As an equal opportunity employer, UT Southwestern prohibits 
unlawful discrimination, including discrimination on the basis of race, color, 
religion, national origin, sex, sexual orientation, gender identity, gender 
expression, age, disability, genetic information, citizenship status, or 
veteran status.  



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in QMUL London

[Aravindan Ilangovan]

Dear All

We are looking for two postdocs with expertise in structural biology to join 
our research group in the Centre for Structural Biology at Queen Mary 
University of London. These Wellcome Trust funded posts will work towards 
understanding the molecular mechanism of DNA replication initiation in 
bacteria. This structural biology project will take advantage of the expertise 
in the lab working with nucleoprotein complexes aided by dedicated cryo-EM and 
X-ray crystallography facilities. The group has routine access to the Titan 
Krios microscopes at LonCEM and eBIC and an in-house computing infrastructure 
for data processing.

Details about the position and a link to the application system can be found 
here https://www.qmul.ac.uk/jobs/vacancies/items/7930.html

Feel free to contact me (a.ilango...@qmul.ac.uk) 
if you have any specific queries about these posts.

Best

Aravindan Ilangovan

Lecturer in Structural Biology
Abernethy Building, QMUL
London, UK
https://www.ilangovan-lab.com/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in structural biology of rRNA modification

[Maria Selmer]

Dear all,

I’m looking for a highly motivated postdoc who will work on structural and 
mechanistic aspects of how rRNA methyltransferases contribute to ribosome 
biogenesis and antibiotic resistance. This will involve a combination of 
structural and biophysical techniques, with a focus on single-particle cryo-EM.

The successful candidate should have a PhD in structural biology, biochemistry 
or biophysics (or a related area) and experience of purification and functional 
or structural characterization of ribosomes and/or RNA, and experience in or 
interest to learn single-particle cryo-EM.

The position is a 2-year postdoc employment with possibility of extension, 
funded by the Swedish Research Council.

Further details and link to application system are found here: 
https://www.uu.se/en/about-uu/join-us/details/?positionId=584582 


Application deadline February 16.

Best regards
Maria

Prof. Maria Selmer
Cell and Molecular Biology, Uppsala University
BMC, Box 596
SE-75124 Uppsala
Sweden

Telephone: +46-(0)18-4714177
https://www.icm.uu.se/structural-biology/selmer-lab/






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


smime.p7s
Description: S/MIME cryptographic signature

[ccp4bb] Postdoc position available at Diamond as part of the NIH funded ASAP consortium developing antivirals

[Walsh, Martin (DLSLtd,RAL,LSCI)]

Dear All
following on from the success of our massive fragment based drug discovery 
effort targeting the main protease of SARS-CoV-2 which led to the COVID 
moonshot initiative (https://postera.ai/moonshot/ ) and has led to things 
working out far more than we would have ever imagined in such a short time 
period (see https://dndi.org/research-development/portfolio/covid-moonshot/ ) 
…..

we now have an exciting opportunity to join our team which is part of one of 
the NIH/NIAID's AViDD 
centers,
 namely AI-driven Structure-enabled Antiviral Platform 
(ASAP)

–So if you are interested in a structure-based drug discovery focused post-doc 
targeting emerging pathogens of concern then look no further – come and join us 
at Diamond – more details here:

https://vacancies.diamond.ac.uk/vacancy/post-doctoral-research-associate-aidriven-structureenabled-antiviral-platform-511397.html
closing date: 5th February 2023

don’t hesitate to contact me directly for more details/questions about the post

Martin
--
Martin A. Walsh (He/Him/His),
Deputy Director Life Sciences &
Group Leader at the Research Complex at Harwell,
Diamond Light Source,
Harwell Science & Innovation Campus,
Didcot OX11 0DE,
UK
T:+44 1235 778518
E:martin.wa...@diamond.ac.uk


-- 
This e-mail and any attachments may contain confidential, copyright and or 
privileged material, and are for the use of the intended addressee only. If you 
are not the intended addressee or an authorised recipient of the addressee 
please notify us of receipt by returning the e-mail and do not use, copy, 
retain, distribute or disclose the information in or attached to the e-mail.
Any opinions expressed within this e-mail are those of the individual and not 
necessarily of Diamond Light Source Ltd. 
Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments 
are free from viruses and we cannot accept liability for any damage which you 
may sustain as a result of software viruses which may be transmitted in or with 
the message.
Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position at Fox Chase Cancer Center, Philadelphia, USA

[Wu, Jinhua]

Dear CCP4 community,

A postdoctoral position is available at Fox Chase Cancer Center, Temple 
University Health System (Philadelphia, PA) for a highly-motivated individual 
in the field of structural biology and protein biochemistry.

Fox Chase Cancer Center is a long-standing NCI-designated Comprehensive Cancer 
Center with multidisciplinary research interests from basic biological sciences 
to drug development and clinical studies. The institute is located in a quiet, 
safe, and convenient neighborhood on the outskirts of the city. It is one of 
the top-ranked work places for postdoctoral researchers in the US.

The research in the lab focuses on structural and mechanistic studies of the 
signaling events mediated by integrins, small GTPases, and kinases, which have 
strong implications in cancer progression, metastasis, and other human 
diseases. We employ these new insights into inhibitor and drug discovery 
(https://www.foxchase.org/people/jinhua-wu). The lab is equipped with top-notch 
crystallographic instruments, including a Mosquito robot, a Formulatrix crystal 
imager, and a brand-new Synergy-S X-ray home source. We also have frequent 
remote beamtimes at BNL and MacChess synchrotrons. The ideal candidates for 
this position should hold a Ph.D. with strong background in X-ray 
crystallography and are also expected to be experienced in construct design, 
protein expression and purification. Prior experience in mammalian cell 
culture, cell signaling, flow cytometry, and cancer biology is desired but not 
required. FCCC offer an outstanding research environment and strong support for 
the career development of our scientists.

If you are interested, please send a cover letter describing previous research 
experience and future plans, a current CV, and a list of three references to: 
jinhua...@fccc.edu.

Regards,
Jinhua


—
Jinhua Wu Ph.D.
Associate Professor
Molecular Therapeutics Program
Fox Chase Cancer Center W410
333 Cottman Ave.
Philadelphia, PA 19111



This electronic message is intended to be for the use of the named recipient, 
and may contain information that is confidential or privileged. This 
communication may contain protected health information (PHI) that is legally 
protected from inappropriate disclosure by the Privacy Standards of the Health 
Insurance Portability and Accountability Act (HIPAA) and relevant Pennsylvania 
Laws. You can direct questions concerning PHI or HIPAA to the Corporate 
Compliance and Privacy Officer at (215) 707-5605. If you are not the intended 
recipient, please note that any dissemination, distribution or copying of this 
communication is strictly prohibited. If you have received this message in 
error, you should notify the sender immediately by telephone or by return 
e-mail and delete and destroy all copies of this message.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in Structural Biology - Cryo-EM of Chromatin Complexes at Halic Lab, SJCRH

[Bilokapic, Silvija]

Hi all

This is an exciting opportunity for a self-motivated scientist to join the 
Structural Biology Department at SJCRH in the laboratory of Dr. Mario Halic. 
The Halic lab studies the epigenetic regulation of gene expression using 
genetics, molecular biology, biochemistry, and structural biology approaches.

The ideal candidate will have extensive experience with biochemical 
methodology, cloning procedures, protein tagging and expression in different 
model organisms, protein and macromolecular complexes purification. Candidates 
should be self-motivated problem-solvers with a high level of accuracy 
especially while multitasking. Experience in structural biology is a plus.

All candidates are expected to have excellent verbal and written communication 
skills, the ability to work independently, and the ability to work 
constructively as a member of a diverse team.



More information about the lab, publications and ongoing projects can be found 
here: https://www.stjude.org/research/labs/halic-lab.html

Applicants should submit CV, cover letter, names and addresses for 3 references 
to mario.ha...@stjude.org. Review of 
applications will begin immediately and continue until the position is filled.



Follow us @LabHalic




Email Disclaimer: www.stjude.org/emaildisclaimer
Consultation Disclaimer: www.stjude.org/consultationdisclaimer



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position at the SGC, University of Toronto

[Levon Halabelian]

A PostDoc position is immediately available at the SGC, University of
Toronto. Details can be found in the following link:
https://www.thesgc.org/careers/toronto/postdoctoral-fellows-structural-biology

APPLICATIONS SHOULD BE SENT TO: [hrsgctoro...@thesgc.org] with the subject
line “SGC Postdoc in Structural Biology”.

Regards,
Levon



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at Duke University

[Seok-Yong Lee]

Dear all,

We are recruiting a postdoc.

A NIH-funded post-doctoral research position is available in the laboratory
of Seok-Yong Lee at the Duke University School of Medicine to study the
structural and mechanistic basis of membrane transport processes. The lab’s
current research focuses on three membrane transport processes: Ca2+ permeation
in somatosensation, drug/metabolite transport, and polysaccharide transport
in microbial cell wall synthesis. The Lee Lab applies a broad
multidisciplinary approach to examine these processes using structural,
biochemical, biophysical, chemical biology, and computational methods. The
successful applicant will work on advancing our mechanistic understanding
of somatosensation into broader biological contexts.



Recent publications from the lab are

Yin et al., *Science*, 2022


Wright, Fedor, et al., *Nature*, 2022


Ren et al., *Nat. Struct. & Mol. Biol.* 2022


Kwon et al., *Nat. Communs.* 2022


Kwon et al., *Nat. Struc. & Mol. Biol*. 2021


Suo et al., *Neuron*, 2020 

Yin et al., *Science*, 2019 



Further information can be found on the Lee lab website (
https://sites.duke.edu/leelab/).



This is a great opportunity for talented biochemists/structural biologists
interested in linking structural biology to sensory neuroscience who would
enjoy being embedded in a scientifically diverse and highly collaborative
group. A strong background in either structural biology (cryo-EM or X-ray)
or membrane protein biochemistry is a plus, but not required.



Interested candidates should send their application material, including
CV/resume, list of publications, a statement of research interests as well
as the contact information of three references, to seok-yong@duke.edu



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in crystallography-driven drug discovery, Yue Lab at Newcastle University

[Wyatt W. Yue]

Dear all


The Yue lab in Newcastle University is currently advertising one postdoc
position in x-ray crystallography, funded for two years in the first
instance, open to all UK/EU/non-EU/international applicants.



https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate/861857001/



You will be a crystallographer working closely with an industry partner
towards small molecule discovery for a rare misfolding disease. You will
carry out crystallography-based fragment screening and biophysical
validation studies to guide compound design for a metabolic enzyme.



You can find out more about our group here:
https://www.staff.ncl.ac.uk/yuelab/



Any informal enquiries you can contact: wyatt@newcastle.ac.uk



Deadline: Friday 18 November 2022. We aim to hold interviews in the week of
28 Nov - 2 Dec 2022.


*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at University of Texas Health Science Center at San Antonio

[Yogesh Gupta]

My research group at UT Health San Antonio
 (UTHSA) is looking for a creative
and self-motivated Postdoctoral Fellow scientist to study the structures
and mechanisms of mRNA modification enzymes. We will use X-ray
crystallography, cryoEM, and enzyme biochemistry to address basic
mechanistic questions and develop strategies for rational drug development.



Below are some of our recent publications:

eLife. 2022 Jan 21;11. PMID: 35060905. doi.org/10.7554/eLife.67150

Nature Communications. 2021 Jun 2; 12: 3287. PMID: 34078893. doi:
10.1038/s41467-021-23594-y


Nature Communications. 2020 Jul 24;11(1):3718. PMID: 32709886. doi:
10.1038/s41467-020-17496-8




The Greehey Children’s Cancer Research Institute (GCCRI) is a unique,
specialized cancer research center focusing on basic and translational
research in childhood cancer and occupies a state-of-the-art 100,000 sq.
foot research facility on the UTHSA’s Greehey Academic Campus. San Antonio
is the nation’s seventh-largest city and is located at the edge of the
beautiful Texas Hill Country. The city offers a rich, multi-cultural
community, affordable cost of living, excellent weather, and a thriving
biomedical industry.



Applicants with prior experience in macromolecular crystallography and a
strong interest in cryoEM studies are encouraged to apply. Interested
candidates can submit their application (CV, a brief description of their
accomplishments, and contacts of 3 references) directly by email to me
(Email: gup...@uthscsa.edu).



Yogesh



Yogesh Gupta, PhD
Associate Professor

University of Texas Health Science Center at San Antonio
Department of Biochemistry & Structural Biology

Greehey Children’s Cancer Research Institute
8403 Floyd Curl Drive, San Antonio, TX, USA 78229

Email: gup...@uthscsa.edu

http://ccri.uthscsa.edu/YGupta.html



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position @ NIH

[Elmlund, Hans (NIH/NCI) [E]]

Dear All,

The Biological Computing Section (BCS) Center for Structural Biology (CSB), 
National Cancer Institute (NCI)—Frederick campus are seeking to recruit a 
postdoctoral fellow. Link to ad below:

https://ccr.cancer.gov/careers/post-doctoral-fellow-electron-microscopy-image-processing-algorithm-development/24314

The job involves development of algorithmic solutions to address the increasing 
demands for quantitative and computational approaches in electron microscopy, 
integrative structural biology, and materials science. The candidate will be 
working in a creative collaborative team developing and applying novel 
computational solutions for analyzing high-dimensional noisy image data.

Best wishes,

Hans Elmlund
--
HANS ELMLUND PhD
Senior Investigator

National Institutes of Health
National Cancer Institute—Frederick Campus
1050 Boyles St, Fredrick MD 21702
United States of America

T:  +1(301)846-5670
M: +1(240)739-9079
E:  hans.elml...@nih.gov
simplecryoem.com



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position at Aarhus University

[Gregers Rom Andersen]

Applications are invited to apply for a 2-year post-doctoral research position 
based on a collaboration between the laboratories of Professors Gregers R 
Andersen (Structural biology) and Jan J Enghild (Protein chemistry and 
biochemistry) at The University of Aarhus in Denmark. Both groups are located 
in the Department of Molecular Biology and Genetics, https://mbg.au.dk/en/

The applicant should have a background in single particle electron microscopy, 
X-ray crystallography or other relevant structural biology approach. Experience 
with protein purification is also required. Prior experience with cryo-electron 
microscopy is preferred, but not strictly necessary. Experience with the Linux 
operating system is also preferable.

The postdoc will join a team applying state-of-the-art techniques of structural 
and molecular biology to investigate the structure and biology of the human 
protein CD109. This is a GPI-anchored cell surface protein that modulates TGFβ 
signaling through direct interactions with TGFβ cytokines and the type I 
receptor TβRI. As a member of the α-macroglobulin protein family, which also 
includes complement factor C3 and human alpha-2-macroglobulin, CD109 has a 
complex multi-domain structure and can exist in multiple conformations.

Facilities available for the project includes:

Protein expression in bacteria and eukaryotic cells, purification with 
state-of-the-art FPLC, and biochemical characterization (amino acid analysis, 
Edman sequencing, mass photometry, BLI, SPR, ITC).

Access to two 300 kV Titan Krios microscopes with Gatan K2 and K3 detectors for 
screening and data collection. There is also access to negative stain EM for 
sample optimization on a 120 kV Technai microscope. Vitrobot and Leica blotting 
devices are available for preparation of grids. There is an in house high 
performance computing cluster dedicated to cryo-EM data processing. More 
information on the cryo-EM environment is available at https://embion.au.dk/

Potential applicants should contact Gregers R Andersen g...@mbg.au.dk for more 
information.

The official call for the position is available at
https://international.au.dk/about/profile/vacant-positions/job/postdoctoral-position-in-characterization-of-cd109s-structure-and-interactions



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at UW-Madison

[Yongna Xing]

Postdoctoral Fellow in Multidisciplinary Structural Biology

Laboratory of Dr. Yongna Xing

McArdle Laboratory of Cancer Research

Wisconsin Institutes for Medical Research (WIMR) II 6451
University of Wisconsin-Madison

 Highland Ave
Madison, WI 53705

A postdoctoral position on multidisciplinary structural biology is available to 
investigate the mechanisms and functions of phosphatase signaling complexes and 
their disease mutations in cancer and intellectual disability. We combine 
cryo-EM, x-ray crystallography, cell biology, system biology, biochemistry, 
computational biology, machine learning, and bioinformatics to gain critical 
knowledge on complex phosphatase signaling networks dictated by both allosteric 
structured cores and versatile signaling motifs. The research is performed in a 
highly multidisciplinary setting with basic scientists with expertise in 
Cryo-EM, biochemistry, cell biology, bioinformatics and chemical biology. We 
are well equipped for multidisciplinary research, such as powerful GPU 
computers, a liquid handling crystallization robot, and a live cell imaging 
system. In addition, our lab is conveniently located near multiple shared 
facilities. Our research is built on collaborations with more than 10 groups 
from US and Europe and dynamic collaborations on campus in basic and clinical 
research. UW-Madison has a highly collaborative research environment that 
easily establishes novel collaborations.

We are seeking productive, and motivated individuals with excellent 
organizational, interpersonal, and communication skills. We expect our 
candidates have strong expertise in cryo-EM, x-ray crystallography, and protein 
biochemistry. We also expect our candidates to feel comfortable expanding their 
expertise and applying in-house bioinformatic tools and machine learning 
algorithms developed in the lab and work both independently and in 
collaboration toward personalized medicine for phosphatase diseases.



The starting salary for the promising candidate will be $54,000 or above.



Review of applications will begin immediately and continue until the position 
is filled. To apply: Please send a cover letter, CV, and the names and contact 
information for three references to Dr. Yongna Xing via email: 
x...@oncology.wisc.edu.



Under-represented minorities are encouraged to apply.


Yongna


___

Yongna Xing, PhD

Professor of Oncology

McArdle Laboratory for Cancer Research

School of Medicine and Public Health

University of Wisconsin-Madison


Tel: 608-262-8376

Email: x...@oncology.wisc.edu



https://mcardle.wisc.edu/who-we-are/mcardle-faculty/yongna-xing-phd

https://mcardle.oncology.wisc.edu/xing/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position on cryo-EM of Ryanodine Receptors - Vancouver, Canada

[Filip Van Petegem]

Dear colleagues,

A postdoctoral position is available to work on ion channel structural
biology in the lab of Filip Van Petegemat the University of British
Columbia (Vancouver, Canada). The project focuses on the regulation and
pathophysiology of Ryanodine Receptors (RyRs) and their associated
proteins. RyRs represent the largest ion channels currently known and are
targets for hundreds of mutations that cause cardiac arrhythmias,
myopathies, and malignant hyperthermia.



The project combines cryo-EM and electrophysiology with various biophysical
methods. For some aspects, X-ray crystallography may be required. Our lab
has steady access to the in-house cryo-EM facility, which houses a Titan
Krios with Falcon IV detector and a 200kV Glacios (Falcon III) for
pre-screening grids, as well as microscopes for negative stain EM.



Minimum requirements for applicants include a PhD in Biochemistry or a
related discipline with extensive experience with one or more structural
biology methods (NMR, X-ray crystallography, or cryo-EM). Direct experience
with membrane proteins is an additional plus.



The lab values diversity and inclusivity, and applicants from all
backgrounds are encouraged to apply. This is an opportunity for people with
a structural biology background to learn electrophysiological methods.



Recent work from the lab includes an investigation of how Ryanodine
Receptors are modulated by small molecules, disease mutations, and
post-translational modification, using cryo-EM, X-ray crystallography,
planar lipid bilayer electrophysiology, and enzyme kinetics.



Recent work on this topic:


Yang et al (2022) *PNAS* 119:e2120416119

Woll et al (2021) *Nature Comm.* 12:807

Ma et al (2020) *Nat Chem Biol*. 16,1246-1254

Haji-Ghassemi et al (2019) *Molecular Cell* 75,1-14


For more information on recent work, see http://crg.ubc.ca/VanPetegem/

The lab is housed within the Life Sciences Centre at UBC (lsi.ubc.ca),
located on the Point Grey campus in Vancouver.


Interested candidates should send a CV, a cover letter showing the
motivation to apply, along with names and contact details for 3 references
to filip.vanpete...@gmail.com.




-- 
Filip Van Petegem, PhD
Professor, Dept. of Biochemistry and Molecular Biology
The University of British Columbia
2350 Health Sciences Mall - Rm 2.356
Vancouver, V6T 1Z3

phone: +1 604 827 4267
email: filip.vanpete...@gmail.com
http://crg.ubc.ca/VanPetegem/

Twitter: @FilipPetegem



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position - Toth Lab at the Institute for Bioscience and Biotechnology Research

[Eric Andrew Toth]

*Position Description: *

The Toth lab at the Institute for Bioscience and Biotechnology Research is
seeking a highly motivated postdoctoral fellow for an NIH-funded research
program aimed at developing designer proteases that selectively destroy
active RAS (see Chen, Y. and Toth, E.A., et al., 2021, *Communications
Biology*, *4*, 299). The overall objective of the research program is to
develop general principles for engineering proteases that can control
signaling in cells, with the RAS family of proteins as our current
proof-of-principal target. The Postdoctoral Fellow will be involved in
research projects involving engineering of candidate RAS-specific
proteases, analysis of protease-substrate complexes, and analysis of the
activity and effects of the proteases in cell models.  The Postdoctoral
Fellow will be expected to independently design and apply molecular
biology, biochemical, and structural biology tools for the expression,
characterization, and structure determination of novel RAS-specific
proteases.

The successful candidate will be able to generate purified recombinant
RAS-specific proteases and RAS proteins, characterize those proteins and
their complexes, and determine the structures of protease and
protease-substrate complexes.  The individual will also analyze the
effectiveness of the RAS-specific proteases in controlling RAS signaling
and cell proliferation in cancer cell models harboring oncogenic RAS
mutants using established cell-based assay techniques.  The individual will
also provide technical direction to laboratory staff, assist the PI in data
management, preparation of manuscripts, grant proposals, and facilitate
operations of the laboratory. This position is funded through March 2025.

*Qualifications:*

The position requires a Ph.D. in biochemistry, molecular biology, or a
closely related discipline.  Candidates who have practical experience in
molecular biology, protein chemistry and/or structural biology will be
considered with the highest priority.  The successful candidate must be
highly motivated with expertise in the fields of structural biology or
biochemistry with a focus on structure-function relationships.  A
particular research focus and interest in in structure determination by
X-ray crystallography or cryoelectron microscopy is preferred.  In
particular, the individual should have extensive experience in biochemistry
as used in the cloning, expression, purification, and characterization of
recombinant proteins, crystallization screening, protein structure
determination, and refinement. Experience in mammalian cell culture and
cell-based assay techniques is preferred.

*Salary:*

Commensurate with qualifications

-- 

*Eric A. Toth, Ph.D. *

Research Assistant Professor
Institute for Bioscience and Biotechnology Research
9600 Gudelsky Drive
Rockville, MD 20850

Email: eat...@umd.edu
Phone: x-240-314-6516



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position available in the lab of Prof. Eddy Arnold (Rutgers University, NJ, USA)

[F. Xavier Ruiz]

Dear All,

We have an immediate opening for a skilled post-doctoral researcher in the 
laboratory of Prof. Eddy Arnold at Rutgers University (NJ, USA).
The aim of the project is to study the structure and function of human viral 
proteins (and polyproteins), including from polymerases from HIV-1, SARS-CoV-2 
and other RNA viruses with pandemic potential, through cryo-electron microscopy 
(and also X-ray crystallography). The funding comes from the recently awarded 
AViDD centers 
(https://cabm.rutgers.edu/news/new-nih-awards-eddy-arnold-lab-antiviral-drug-discovery)
 and the HIVE center (http://www.hivecenter.net/).

For more information about the position, please see the full advert: 
https://jobs.rutgers.edu/postings/166341

Interested candidates should apply via the above link. For informal inquiries, 
please feel free to contact me directly.

Best wishes, 

Xavi

F. Xavier Ruiz
Assistant Research Professor
Arnold Laboratory
Center for Advanced Biotechnology and Medicine
Rutgers University

Websites: https://cabm.rutgers.edu/person/francesc-x-xavi-ruiz-figueras
   https://publons.com/researcher/1525897/francesc-xavier-ruiz/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at the National Cancer Institute in computational structural biology

[Philippe Youkharibache]

A A post-doctoral position is available in the Cancer Data Science Lab in 
computational structural biology to study the structure and function of cell 
surface proteins and engineer optimized chimeric antigen receptor constructs, 
integrating structural, biophysical and biological constraints.  It is a key 
position in an interdisciplinary project bridging structural biology (cryoEM, 
NMR, Xray), computational biology, cell biology and clinical trials.

https://ccr.cancer.gov/careers/post-doctoral-fellow-molecular-modeling-computational-biology/25047
 
 
Chimeric Antigen Receptors (CAR) are the backbone of CAR-T cell therapies 
(https://www.cancer.gov/about-cancer/treatment/research/car-t-cells). They are 
the focus of over 700 clinical studies being conducted worldwide.  Many teams 
throughout the world are focusing on the optimization of CAR-Ts for the 
treatment of patients with relapsed/refractory cancers but the vast majority of 
studies are performed by an empirical trial and error approach.  This project 
brings together expertise in CAR-T cell biology, structural biology, 
computational structural modeling and machine learning to develop a rational 
design approach.
 
Qualifications:
The candidates should hold a Ph.D. degree, have at least one first author 
publication and have a strong knowledge of protein structure.  Experience in 
protein modeling, molecular dynamics simulations (Amber, NAMD, CHARMM, Gromacs 
etc.), and biophysics methods is needed. Artificial Intelligence (Machine 
learning) experience and/or software development experience are a plus but not 
required.
 
To Apply:
Interested individuals should send a cover letter outlining research interests 
and long-term goals, CV and the names of three references to:
Philippe Youkharibache, Ph.D. philippe.youkhariba...@nih.gov
 
 
The NIH is dedicated to building a diverse community in its training and 
employment programs and encourages the application and nomination of qualified 
women, minorities, and individuals with disabilities. DHHS and NIH are Equal 
Opportunity Employers.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position in mitochondrial structural and cellular biology - Center for Protein Research, University of Copenhagen (Kummer)

[Eva Kummer]

Dear all,


we are looking for an excellent, highly motivated and self-organized 
postdoctoral candidate to join our young group at the Center for Protein 
Research at the University of Copenhagen. The postdoc project aims to 
investigate how mitochondria maintain the integrity of their genetic 
information using molecular cell biology and single particle cryo-EM. We are 
specifically looking for someone with significant experience in mammalian cell 
culture techniques, purification of recombinantly expressed proteins and strong 
proficiency in cryo-electron microscopy (single particle or cryo-ET). At CPR, 
you will join a collaborative and international environment.


The position is available from 01 October 2022 or as soon as possible 
thereafter.


For more information, please visit: 
https://employment.ku.dk/faculty/?show=156551

The Center for Protein Research hosts research groups of different disciplines 
ranging from systems biology, proteomics, and chemical biology, to disease 
biology. The primary methodological approaches of our laboratory are single 
particle cryo-electron microscopy and protein and RNA biochemistry. Our group 
profits from generous funding by an NNF-CPR core grant and a Hallas Møller 
Emerging Investigator grant from the Novo Nordisk Foundation. We have access to 
a fully equipped mammalian and insect cell culture facility in house and 
state-of-the-art fluorescence and electron microscopy instrumentation at CPR 
and CFIM (Core Facility for Integrated Microscopy at the University of 
Copenhagen). In addition, CPR entertains several core facilities including 
protein production, crystallography, biophysics, high performance computing, 
mass spectrometry, and genomics.

Please get in touch for informal inquiries via eva.kum...@cpr.ku.dk

Application deadline is 14 June 2022. Application will have to be submitted via 
the online application portal of Copenhagen University.

I am looking forward to be hearing from you.
With best wishes,
Eva


Eva Kummer
Group Leader / Associate Professor

University of Copenhagen
Novo Nordisk Foundation Center for Protein Research
Protein Structure and Function Program
Blegdamsvej 3B
2200 København N




https://www.cpr.ku.dk/research/protein-structure-function-program/kummer/





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in the Marcia lab (EMBL) - deadline May 31st

[Marco MARCIA]

Dear colleagues,
please note this 2-year postdoc position available in my lab at EMBL 
Grenoble to work on long non-coding RNA structure/function!

Kindly distribute it to potentially interested candidates.
Deadline for application is on May 31st and more info on the position, 
plus the link to submit the application can be found at:


https://www.embl.org/jobs/position/GR00182

Thank you!
Marco




--
Dr. Marco MARCIA
Group Leader
EMBL Grenoble
71 Avenue des Martyrs, room 254
38042 Grenoble Cedex 09
France
phone (lab): 0033-(0)476207634
phone (office): 0033-(0)476207759
fax: 0033-(0)476207199
email: mmar...@embl.fr
web: https://www.embl.org/groups/marcia/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position at Fox Chase Cancer Center, Philadelphia, USA

[Wu, Jinhua]

A postdoctoral position is available at Fox Chase Cancer Center, Temple 
University Health System (Philadelphia, PA) for a highly-motivated individual 
in the field of structural biology and protein biochemistry.

Fox Chase Cancer Center is a long-standing NCI-designated Comprehensive Cancer 
Center with multidisciplinary research interests from basic biological sciences 
to drug development and clinical studies. The institute is located in a quiet, 
safe, and convenient neighborhood at the outskirts of the city. It is one of 
the top-ranked work places for visiting scholars and postdoctoral researchers 
in the US.

The research in the lab focuses on structural and mechanistic studies of the 
signaling events mediated by integrins, small GTPases, as well as kinases, 
which have strong implications in cancer progression, metastasis and other 
human diseases, and employing these new insights into inhibitor/drug discovery. 
 (https://www.foxchase.org/people/jinhua-wu.). The lab is equipped with 
top-notch crystallographic instruments including a Mosquito robot, a 
Formulatrix crystal imager, and a brand-new Synergy-S X- ray home source. We 
also have frequent remote beamtimes at BNL and MacChess synchrotrons.  The 
candidate should hold a Ph.D. degree with strong experience in X-ray 
crystallography, protein biochemistry, and molecular biology. Prior experiences 
in mammalian cell culture, flow cytometry, drug screen, and cancer biology, are 
desired but not required. We also offer an outstanding research environment and 
strong support for the career development for our scientists.

If you are interested, please send a cover letter describing previous research 
experience and future plans, a current CV, and a list of three references to: 
jinhua...@fccc.edu.

Best,
Jinhua

—
Jinhua Wu Ph.D.
Associate Professor
Molecular Therapeutics Program
Fox Chase Cancer Center W410
333 Cottman Ave.
Philadelphia, PA 19111
215-728-2867 (office)
215-728-3616 (fax)





This electronic message is intended to be for the use of the named recipient, 
and may contain information that is confidential or privileged. This 
communication may contain protected health information (PHI) that is legally 
protected from inappropriate disclosure by the Privacy Standards of the Health 
Insurance Portability and Accountability Act (HIPAA) and relevant Pennsylvania 
Laws. You can direct questions concerning PHI or HIPAA to the Corporate 
Compliance and Privacy Officer at (215) 707-5605. If you are not the intended 
recipient, please note that any dissemination, distribution or copying of this 
communication is strictly prohibited. If you have received this message in 
error, you should notify the sender immediately by telephone or by return 
e-mail and delete and destroy all copies of this message.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at IECB, Bordeaux, France

[Pierre Maisonneuve]

Dear colleagues, 
 
We have an open position for a highly motivated postdoctoral candidate in my 
group at the European Institute of Chemistry and Biology (IECB) to investigate 
the structural basis of the regulation protein kinases and pseudokinases 
receptors in human signaling by using cryo-EM and X-ray crystallography. 
 
Applicants must have a Ph.D. (or due to complete within 6 months) in 
biochemistry, biophysics, life science or related fields. We are seeking a 
person with expertise in protein biochemistry (ideally in membrane protein) and 
with knowledge in single-particle electron microscopy (cryo-EM). Previous 
experience in protein expression in eukaryotic cells (insect and human) is 
preferred but not required.

The position is funded for 2 years, but the candidate is encouraged to apply 
for additional postdoctoral funding.

The candidate will join an exciting and multidisciplinary scientific 
environment with on-site access to cutting-edge facilities in cryo-EM (housing 
a 200kV Arctica equipped with a K2 summit camera and soon to come 200kV 
Cryo-electron microscope equipped with an energy filter and last generation 
direct detector), X-Ray crystallography, NMR, Biochemistry, Biophysics, 
molecular biology and cell biology. The project involved international 
collaborations with cell biologists for complementary characterization of 
protein function in cell and in mice.  

Interested applicants should submit a cover letter, CV and contact information 
of 2 references here:  
https://emploi.cnrs.fr/Offres/CDD/UMR5248-PIEMAI-001/Default.aspx?lang=EN 

 
The deadline for the application is May 30th. The starting date for this 
position is October 1st.

Example of work that we are developing in the lab:
 
Posternak G*, Tang X*, Maisonneuve P*, Jin T*, Lavoie H* et al., Functional 
characterization of a PROTAC directed against BRAF mutant V600E. Nature 
Chemical Biology. 2020 Nov;16(11):1170-1178. *Equal Contribution
 
Lavoie H*, Sahmi M*, Maisonneuve P* et al., MEK drives BRAF activation through 
allosteric control of KSR proteins. Nature. 2018 Feb 22;554(7693):549-553. 
*Equal Contribution

Best,

Pierre

*
Pierre Maisonneuve Ph.D.

Group Leader
UMR 5248 - Chemistry & Biology of Membranes and Nano-Objects
CNRS - Université de Bordeaux

Institut Européen de Chimie et Biologie
Phone: +33(0)5 40 00 35 88
@: p.maisonne...@iecb.u-bordeaux.fr 
2 rue Robert Escarpit, 
33607 Pessac, France
**
Please consider the environment before printing this email.


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position at MRC-LMB, Cambridge UK

[Suyang Zhang - MRC LMB]

Dear colleagues,

My lab at the MRC-Laboratory of Molecular Biology is recruiting a postdoc
to work on transcription-coupled alternative splicing. We are looking for
candidates with a strong background in biochemistry or cell biology and
experience in mammalian cell culture as well as cell line engineering.

Details of the position and how to apply can be found here:
https://www.nature.com/naturecareers/job/postdoctoral-scientist-structural-studies-dr-suyang-zhang-lmb-1815-mrc-laboratory-of-molecular-biology-756703

Please feel free to contact me by email: szh...@mrc-lmb.cam.ac.uk

Best regards,
Suyang Zhang

Structural Studies Division
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge CB2 0QH, UK



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at SBBS, QMUL

[Vidya Darbari]

A Postdoctoral Research Assistant position is available at Queen Mary 
University of London (QMUL) to work with Professor Richard Pickersgill, Dr 
Vidya Darbari, and Dr Arianna Fornili in collaboration with Dr Vladimir 
Shevchik (University of Lyon) on the structure of the type II secretion system 
assembly platform. The post-holder will be funded by BBSRC on a project 
entitled “Structure of the assembly platform of the bacterial type II secretion 
system”.

The post-holder will conduct research to understand the molecular organisation 
and structure of the assembly platform of the type II secretion system. The 
project involves producing inner membrane assembly complexes and determining 
their structures using cryo-electron microscopy. Key techniques will include 
molecular biology, biochemistry, and cryo-electron microscopy. Prior experience 
in as many of these techniques as possible is desirable. The post-holder will 
join a multidisciplinary team with frequent interactions.

The start date is July 2022 or as soon as possible thereafter. The post is 
full-time and available until July 2025.

For further information and to apply, please refer to the link: 
https://www.findapostdoc.com/search/job-details.aspx?jobcode=10458

Best Regards
Vidya

Dr Vidya Chandran Darbari
Lecturer in Structural Biology
Biochemistry Program Tutor
Deputy Director of Graduate Studies

School of Biological and Behavioural Sciences
Office: 3.18 Abernathy Building
Lab: Blizzard Institute
Queen Mary University of London



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position at the Department of Biochemistry and Redox Biology Center, the University of Nebraska-Lincoln

[limei zhang]

Dear all,
Our group has an opening for several research opportunities. Please see the 
details below.
Thanks for your time!
Limei Zhang
Associate Professor
Department of Biochemistry/Redox Biology Center
University of Nebraska-Lincoln
Email: limei.zh...@unl.edu
http://biochem.unl.edu/limei-zhang

Postdoctoral Position at the Department of Biochemistry and Redox Biology 
Center University of Nebraska-Lincoln, Lincoln NE, USA

A postdoc position is available in Dr. Limei Zhang’s group at the Department of 
Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, for 
highly motivated candidates who are interested in structural biology, redox 
biology and infectious disease. The position will offer a competitive salary 
and benefits.
Zhang Group: With funding support from both NIH and NSF, the Zhang Group 
applies a suite of interdisciplinary tools to investigate the 
structure-mechanism relationships of metalloproteins in redox reactions, stress 
responses and antibiotic resistance. For more information about the Zhang 
Group, please visit the website: https://biochem.unl.edu/limei-zhang.
Job responsibilities: The postdoctoral fellow is expected to independently 
design and conduct high-quality research experiments for the assigned project 
under the supervisor’s guidance; analyze data and draft manuscripts for 
publication; take roles in the lab maintenance with other group members; and 
assist the supervisor to mentor undergraduate and graduate students.
Qualifications: The required qualifications include a recent Ph.D. degree (or 
expected soon) in biochemistry, biophysics, chemistry, microbiology or a 
related field; a strong record in conducting high-quality research in protein 
biochemistry or biophysics. Experience in structural biology (X-ray 
crystallography, cryo-EM or nuclear magnetic resonance) is highly desirable but 
not required.
Training: The postdoc fellow will have the opportunity to learn comprehensive 
methods for preparation and characterization of metalloproteins in the Zhang 
group and the first-hand training in cryo-EM in the collaborating research 
center supported by the NSF EPSCoR Research Fellowship.
The University of Nebraska-Lincoln is located in a vibrant and safe city 
offering an outstanding and affordable quality of life, and numerous 
multi-cultural and entertainment benefits. The Redox Biology Center is 
organized as a broad-based interdisciplinary and multi-institutional entity 
involving researchers from the University of Nebraska-Lincoln and the 
University of Nebraska Medical Center in Omaha and offers a supportive and 
collaborative international environment as well as access to cutting edge 
proteomics, metabolomics, crystallography, and NMR facilities. We are also 
expected to have a cryo-EM instrument (Glacios w/Falcon 4i, Selectris EF & 
Ceta-D camera) installed at UNL in late 2022.
Recognizing that diversity within a context of inclusivity enhances creativity, 
innovation, impact, and a sense of belonging, the Institute of Agriculture and 
Natural Resources (IANR) and the Department of Biochemistry are committed to 
creating learning, research, Extension programming, and work environments that 
are inclusive of all forms of human diversity. We actively encourage 
applications from and nominations of individuals from underrepresented groups.
To apply for the position, please submit a letter of interest with a short 
summary of past research experience; your curriculum vitae, and contact 
information for three professional references, including phone numbers and 
emails to limei.zh...@unl.edu
As an EO/AA employer, qualified applicants are considered for employment 
without regard to race, color, ethnicity, national origin, sex, pregnancy, 
sexual orientation, gender identity, religion, disability, age, genetic 
information, veteran status, marital status, and/or political affiliation. See 
http://www.unl.edu/equity/notice-nondiscrimination.
Thanks for your attention,





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in structural biology at UC Riverside

[Jikui Song]

Position Description: A post-doctoral position is immediately available for 
highly motivated, hard-working candidates to join Dr. Jikui Song’s group in the 
Department of Biochemistry at University of California, Riverside. Dr. Song’s 
research group employs collaborative and multidisciplinary approaches to 
investigate mechanistic basis of cancer epigenetics, in particular chromatin 
modifications that are essential for gene regulation and development. We are 
also exploring the mechanistic basis and regulatory mechanisms of viral 
replication, toward identification of effective therapeutical strategies 
against viral infection. The project will involve structural and dynamic 
characterization of macromolecular complexes using cryo-EM, X-ray 
crystallography, single-molecule FRET and other biochemical/biophysical 
approaches. Examples for recent publications include Zhang et al. Nature (2018) 
554:387-391, Wang et al. Nat. Struct. Mol. Biol. (2020) 27: 875-885, Gao et al. 
Nat. Commun. (2020) 11:3355, and Ren et al. Nat. Commun. (2021) 12:2490. 

Research Environment: The NIH-funded research in the Song lab aims to uncover 
the fundamental principles underlying epigenetic regulation and pathogen-host 
interaction. The successful candidates will have extensive opportunities for 
multiple collaborations with scientists at UC Riverside and worldwide. UC 
Riverside is located at the metropolitan area of Los Angeles. Such an 
environment allows one to have a good balance of life and science.

Qualification and Experience: Successful candidates will have a recent PhD in 
structural biology, biophysics or other related fields, with extensive 
experience in protein production, biochemical characterization and structural 
analysis. Additional background in cryo-EM is highly desirable. Applications 
will be reviewed as they are received. The position will remain open until 
filled. Postdoctoral salary will be commensurate with prior research experience 
and qualifications.

Application: Interested applicants should send curriculum vitae, expected 
starting date, brief summary of previous research experience, and contact 
information of 2-3 references as one single PDF file to Jikui Song, Ph.D. 
Department of Biochemistry, University of California, Riverside, CA 92521 
(Email: jikui.s...@ucr.edu). 

More information can be found in https://songlab.ucr.edu.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at Rice Unversity, Houston

[Yang Gao]

Dear All,

A postdoctoral position is available in Dr. Yang Gao’s Lab 
(http://yanggaolab.blogs.rice.edu/) at Rice University, Houston, TX. Our lab 
studies enzymes and motors in DNA replication and repair (Science 363 (6429), 
eaav7003; Science 352 (6291), 1334). We combined biochemical, and biophysical 
techniques with cryo-electron microscope and crystallography to investigate how 
the genomic DNA is replicated and maintained. In addition, we explore 
structural-based drug screening (PMID: 34900730) and protein engineering (Yang, 
et. al. under revision, Nat. Chem. Biol.). Previous experiences with protein 
cloning, expression, and purifications are needed. Experiences in 
crystallography and cryo-EM are a plus but not stickily required. Candidates 
with experience in biochemical reconstitution and characterizations of large 
enzyme complexes are more than welcome.

Interested candidates please contact Yang at y...@rice.edu for details. 

Best
Yang 

Yang Gao
Assist. Prof., CPRIT Scholar
Department of BioSciences
Rice University



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position @ MPI NAT, Goettingen

[Sonja Lorenz]

Dear colleagues,

my group is looking to hire a motivated postdoc with experience in cell 
biology, a keen interest in proteomics, and the ability to communicate with 
structural biologists. 
It would be fantastic if you could forward the ad below to suitable candidates 
and/or circulate it within your institutes.

Many thanks for your help and best wishes,
Sonja Lorenz
Independent Group Leader
Ubiquitin Signaling Specificity
Max Planck Institute for Multidisciplinary Sciences
Am Fassberg 11
37077 Goettingen
Germany


——
Max Planck Institute for Multidisciplinary Sciences, Göttingen/Germany

The Max Planck Institute for Multidisciplinary Sciences in Göttingen is an 
internationally leading research institute of exceptional scientific breadth. 
The largest institute of the Max Planck Society, it comprises more than 40 
research groups and employs around 1,000 people from over 50 nations.

The research group Ubiquitin Signaling Specificity (Dr. Sonja Lorenz) invites 
applications for a position as

Postdoc (f/m/d)
– Cell biology of ubiquitin ligase complexes –

Our lab aims to understand how ubiquitin − a single, small protein − achieves 
specificity in regulating virtually all aspects of eukaryotic cell biology. A 
major key lies in the action of ubiquitin ligases, the most diversified class 
of enzymes of the ubiquitin system. The immense potential of ubiquitin ligases 
as therapeutic targets is illustrated by the clinical efficacy of thalidomide 
and derivatives in the treatment of hematologic malignancies. However, progress 
towards rationally manipulating these enzymes has been impeded largely by our 
insufficient understanding of their integration into macromolecular complexes 
and the associated structural and functional consequences. We aim to identify 
and characterize macromolecular complexes of ubiquitin ligases to decipher the 
molecular basis of their specificities in substrate recognition and ubiquitin 
chain formation. To this end, we combine chemical-biological, biochemical, cell 
biological, and structural approaches with a particular focus on cryo-electron 
microscopy.

We have a fully-funded postdoc position available for a talented individual to 
uncover cellular ubiquitin ligase assemblies implicated in neurodevelopmental 
disorders.

Your profile:

You have a PhD or equivalent degree in a relevant subject area, such as cell 
and molecular biology, biochemistry or biomedicine.
You have a proven track record in molecular cloning and cell biology, 
specifically in one or more of the following techniques: Crispr/Cas9-mediated 
gene editing, RNA interference, cell fractionation, co-IP, immunofluorescence, 
and live-cell imaging.
Additional experience in neuronal cell culture and/or proteomics will be 
beneficial.
You are curiosity-driven and eager to interact with biochemists and structural 
biologists.
 You are passionate about science and keen to establish creative new approaches 
to tackle challenging protein complexes.
You are self-motivated and independent, and enjoy being part of an 
international, multidisciplinary team.

About us:

We are an independent research group at the Max Planck Institute for 
Multidisciplinary Sciences, one of Germany’s premier research campuses with 
leading-edge infracture in all fields of structural and cell biology. We are a 
highly international and interdisciplinary team, funded by the Max Planck 
Society, the German Research foundation, and the EMBO YIP. The historic city of 
Goettingen, located in the center of Germany, offers great outdoor and cultural 
opportunities, a bustling student scene, and an impressive scientific heritage.

Position details:

The position should be filled as soon as possible, but the exact start date is 
flexible. The position is initially for 2 years with the possibility of 
extension. Payment and benefits are based on the TVöD guidelines.

The Max Planck Society is committed to increasing the number of individuals 
with disabilities in its workforce and therefore encourages applications from 
such qualified individuals. The Max Planck Society strives for gender and 
diversity equality. We welcome applications from all backgrounds.

Application:

Please submit your application including cover letter (explaining background 
and motivation), CV, transcripts, and publication record by e-mail as a single 
PDF file to the email address below. Review of applications will begin 
immediate. Informal inquiries are also welcome.

ausschreibung26...@mpibpc.mpg.de 
Max Planck Institute for Multidisciplinary Sciences
Research Group „Ubiquitin Signaling Specificity“
Dr. Sonja Lorenz
Am Fassberg 11
37077 Göttingen
Germany

Twitter @SLorenzLab

Lab Homepage: https://www.mpinat.mpg.de/lorenz 



To unsubscribe from the CCP4BB list, click the following link:

[ccp4bb] Postdoc position at Imperial College, London

[Low, Harry H]

Dear all,
A postdoctoral position is available in the lab focussed on understanding the 
role and mechanism of ESCRT-III-like membrane remodelling proteins in bacteria 
(for example https://pubmed.ncbi.nlm.nih.gov/34166615/). Core techniques will 
include cryoEM SPA and tomography. The position is funded by the BBSRC and is 
available for four years.

For further details please see 
https://www.imperial.ac.uk/jobs/description/MED03064/research-associate or 
contact Harry Low informally h@imperial.ac.uk. 
The lab webpage can be found at www.thelowlab.org.

The closing date for applications is 21st April 2022.

Regards,
Harry







__
Dr. Harry Low
Wellcome Trust Senior Research Fellow
Department of Infectious Disease
366 Sir Alexander Fleming Building
Imperial College
London, SW7 2AZ
+44 207 594 3064




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position at SGC-TORONTO

[Levon Halabelian]

Hi All,

A PostDoc position is immediately available at the SGC, University of
Toronto. Details can be found in the following link:
Postdoctoral Fellows in Structural Biology | SGC (thesgc.org)


Regards,
Levon



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at Imperial College London

[Bubeck, Doryen A]

Dear all,

I wanted to call your attention to an exciting job opportunity that integrates 
cryoEM and membrane biophysics to understand how the immune system fights 
infection. The position is funded by a Wellcome Trust Investigator Award in the 
labs of Doryen Bubeck (Imperial College London) and Mark Wallace (Kings College 
London). Please see below for details on the position and how to apply.

Best wishes,

Doryen Bubeck

_

Dr. Doryen Bubeck
Director Centre for Structural Biology
Department of Life Sciences
Imperial College London

https://www.imperial.ac.uk/people/d.bubeck
@bubecklab


Job Summary

The Bubeck laboratory (https://www.imperial.ac.uk/people/d.bubeck) is looking 
to recruit a Research Associate with high level of expertise in cellular 
tomography. Additional expertise in microbiology is very suited for the 
position.

Duties and responsibilities

This post, funded by a highly competitive Wellcome Trust Investigator Award, 
aims to uncover how the membrane attack complex (MAC) kills bacterial 
pathogens. The project’s primary objective is to discover 1) where MAC is 
located within the bacterial envelope and 2) how does MAC activation control 
bacterial killing. You will join an exciting interdisciplinary team of 
structural biologists and membrane biophysicists to tackle a major question in 
understanding host-pathogen interactions. The project focuses on cryo electron 
tomography-based studies of MAC within the context of a series of model 
membrane systems. The research builds on the lab’s strong track-record in 
complement structural biology and is closely linked with research activities in 
membrane biophysics with Prof. Mark Wallace 
 at King’s College London.

Essential requirements

You will have a PhD (or be near completion of) in structural biology, ideally 
with experience in cellular tomography. You must have a strong research track 
record in studying protein-protein and protein-membrane complexes preferably 
demonstrated by first author publications in international journals. Experience 
in the design and execution of workflow for structure determination of proteins 
or cellular systems from sample preparation to acquisition and analysis of 
structural biology data.

You must have excellent verbal and written communication skills, and be able to 
write clearly and succinctly for publication. You must also be able to relate 
well with others, form positive relationships with a wide range of people and 
to work as part of a team, as well as independently. The ability to develop and 
apply new concepts and have a creative approach to problem-solving, to set and 
attain research objectives in a multidisciplinary team are also essential.

Further Information

This is a full-time, fixed-term appointment available for up to three years, 
with the possibility of extension. You will be based at South Kensington Campus.

Candidates who have not yet been officially awarded their PhD will be appointed 
as Research Assistant within the salary range, £36,694- £39,888 per annum.

Informal enquiries to Dr. Doryen Bubeck: 
d.bub...@imperial.ac.uk

Closing date is 30 March 2022.

To apply 
https://www.imperial.ac.uk/jobs/description/NAT01088/research-associate-structural-biology



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in the Marcia lab (EMBL) - deadline Feb 25th

[Marco MARCIA]

Dear colleagues,
please note this 2-year postdoc position available in my lab at EMBL 
Grenoble to work on long non-coding RNA structure/function!

Kindly distribute it to potentially interested candidates.
Deadline for application is on February 25th and more info on the 
position, plus the link to submit the application can be found at:


https://www.embl.org/jobs/position/GR00178

Thank you!
Marco



--
Dr. Marco MARCIA
Group Leader
EMBL Grenoble
71 Avenue des Martyrs, room 254
38042 Grenoble Cedex 09
France
phone (lab): 0033-(0)476207634
phone (office): 0033-(0)476207759
fax: 0033-(0)476207199
email: mmar...@embl.fr
web: https://embl.fr/research/unit/marcia/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position available at the University of Chicago

[Minglei Zhao]

Dear All,
A postdoctoral position is available in my lab in the Department of 
Biochemistry and Molecular Biology at the University of Chicago. Research in 
the lab is centered at the interface of chemistry and biology. We are 
interested in the structure and function of molecular machines involved in 
post-transcriptional and post-translational modifications, such as mRNA 
methylation and protein ubiquitination. Structural biology techniques including 
X-ray crystallography and cryo-electron microscopy are used in the lab. For 
more information and recent publications, please visit our website 
(https://zhaolab.uchicago.edu ).

UChicago has a long tradition of research excellence and a stimulating 
environment. It also has a state-of-the-art cryo-EM facility housing a Titan 
Krios, an incoming Glacios, an Aquilos cryo-FIB and a VolumeScope. In addition, 
UChicago operates Argonne National Laboratory for the Department of Energy, 
which is home to the Advanced Photon Source (APS), one of the world’s largest 
synchrotron facilities.

The position will be fully funded by UChicago and NIH under NIH guidelines. 
Qualified applicants should have or expect a Ph.D. degree in molecular biology 
or related fields, be highly self-motivated, and demonstrate ability for 
rigorous scientific research with publications in peer-reviewed journals. The 
candidate is expected to have expertise in molecular biology and a strong 
ability to learn new techniques. Previous experience in structural biology is 
desired but not required. Experience in chemical biology, protein engineering, 
cell biology and protein biochemistry is a plus.

Please send a CV and contact information of three references to: 
mlz...@uchicago.edu .

Thank you for your attention.



Best regards,

Minglei


Minglei Zhao, Ph.D.
Assistant Professor
Department of Biochemistry and Molecular Biology
University of Chicago
GCIS W204  
929 E. 57th Street 
Chicago, IL 60637
Tel: (773) 834-3293
https://zhaolab.uchicago.edu 



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at USP (São Carlos, Brazil)

[Rafael Marques]

The Sérgio Mascarenhas Biophysics and Structural Biology Group, from IFSC/USP, 
is looking for exceptionally motivated and innovative candidates to carry out a 
postdoctoral fellowship in the Thematic Project “Septin filaments: structure, 
polymerization and action in pathologies” to develop a project using Cryo-EM as 
the main technique. In addition, negative staining electron microscopy, MALS 
and SAXS can also be used to determine the oligomerization state, shape and 
homogeneity of septin complexes.

Candidates must have a PhD degree obtained no more than 7 years ago and 
experience in protein purification.

Experience in Structural Biology and Cryo-EM are desirable, but not mandatory.

This opportunity is open to applicants of all nationalities.

Interested candidates should send, by February 25th, to the project 
coordinator, Richard C. Garratt (rich...@ifsc.usp.br ), the following documents 
for registration:

– A letter presenting your interest;
– A short CV, presenting academic background, publications, and information 
that proves your scientific experience;
- Letter of recommendation.


Best Regards

Rafael Marques da Silva
Mestrando em Física Biomolecular
Universidade de São Paulo

Bacharel em Ciências Biológicas
Universidade Federal de São Carlos

phone: +55 16 99766-0021

   "A sorte acompanha uma mente bem treinada"





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position in structural biology

[Shaun Olsen]

Dear Colleagues,

A postdoctoral position is immediately available for a highly motivated 
individual interested in elucidating molecular mechanisms of ubiquitin 
signaling.  Research is focused on the enzymatic machinery responsible for 
protein ubiquitination, in particular, large protein complexes involved in 
regulating DNA repair and immunity.  These issues will be addressed using a 
multidisciplinary approach that includes cryo-EM and X-ray crystallography, 
complemented with biochemical/biophysical techniques and cell-based assays.

Successful candidates will join a vibrant scientific community and enjoy 
frequent access to state-of-the-art cryo-EM instrumentation including a Glacios 
TEM equipped with a Falcon 4 direct electron detector and Selectris Imaging 
Filter that are the centerpiece of our new cryo-EM facility.  Access to 
outstanding X-ray crystallography and NMR resources will also be abundantly 
available.

Candidates should hold a recently obtained PhD in biochemistry, chemistry, or 
related subject.  Demonstrated expertise in cryo-EM is highly desirable, though 
individuals with expertise in X-ray crystallography, protein chemistry, and/or 
the biochemical analysis of protein ubiquitination will also be considered.  
Experience with protein expression in insect and mammalian cells is a plus.


Interested candidates should e-mail a cover letter, CV, and the names of three 
references to: ols...@uthscsa.edu.

Shaun K. Olsen
Associate Professor
Department of Biochemistry & Structural Biology
University of Texas Health Science Center at San Antonio
7703 Floyd Curl Drive, BSB413C/414C
San Antonio, TX 78229
Phone: 210-450-3091
E-mail: ols...@uthscsa.edu



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position in Structural Biology of Gene Silencing and DNA Replication at CSHL

[Joshua-Tor, Leemor]

Applications are invited for enthusiastic postdoctoral and/or senior scientists 
in my lab at Cold Spring Harbor Laboratory to work on the structure and 
mechanism of gene silencing pathways or DNA replication. Please see our web 
page for more details (http://joshua-torlab.labsites.cshl.edu/).

Positions are available for highly motivated, enthusiastic and outstanding 
applicants with a PhD and experience in structural biology.

We have a Titan Krios cryo electron microscope equipped with a K3 Gatan camera, 
and enjoy extremely frequent access. We also have a screening microscope (Talos 
120C), and are about to install a chameleon system for grid preparation. We 
also have an excellent fully equipped X-ray facility, crystallization robots 
and fantastic computational resources including high-performance and GPU 
computers. Combined with the nearby NSLS-II, these are exciting times with 
exciting capabilities. Our lab is equipped with state-of-the-art equipment for 
studying macromolecular interactions, and CSHL has an array of cutting-edge 
core facilities.

Cold Spring Harbor Laboratory (CSHL) provides a unique, stimulating and very 
collaborative environment for scientific interactions. Located on the North 
Shore of Long Island, CSHL is in a beautiful setting and is a wonderful place 
to expand one’s knowledge of biology in many different areas, particularly via 
CSHL’s internationally acclaimed Meetings and Conferences, which our scientists 
can freely attend. CSHL also hosts the exciting cryoEM, macromolecular 
crystallography, gene expression, protein purification and many more relevant 
courses, which bring in the leading experts in the field. For details about 
CSHL please see our web site at: http://www.cshl.edu/

Please send CV, list of publications, a summary of research experience and 
interests, and contact information of three references to lee...@cshl.edu.

Leemor
Leemor Joshua-Tor, Ph. D.
HHMI Investigator
W. M. Keck Professor of Structural Biology
Cold Spring Harbor Laboratory
1 Bungtown Road
Cold Spring Harbor, NY 11724
p: (516) 367-8821
e: lee...@cshl.edu
w: 
http://joshua-torlab.labsites.cshl.edu




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position: cryoEM of membrane protein complexes in Paris IBPC

[Valerie Biou]

dear colleagues,

A postdoc position with EU/CNRS co-funding is open to study protein complexes 
involved in heme import in bacteria. Funding is for two years with a possible 
third year. 
We are looking for a very motivated candidate with strong background in 
single-particle cryo-EM sample preparation, data collection and processing or a 
strong knowledge of membrane protein biochemistry. Candidates should not have 
spent more than 12 months in France during the last 3 years. 

This is part of a Cofund fellowship programme with lots of additional benefits.
http://labexdynamo.ibpc.fr/fp-dynamo-paris/ 
http://labexdynamo.ibpc.fr/postdoc-heme-import-in-bacteria-structural-studies-of-transmembrane-protein-complexes/

Contact: valerie.b...@ibpc.fr
Deadline: March 27, 2022
to apply: https://www.euraxess.fr/jobs/734593
https://emploi.cnrs.fr/Candidat/Offre/FR550-MAGTOR-004/Candidater.aspx

Sincerely,

Valérie Biou, Ph.D. valerie.b...@ibpc.fr
Laboratoire de Biologie Physico-Chimique des Protéines Membranaires
umr7099.ibpc.fr 
UMR 7099 CNRS/Univ. de Paris
Institut de Biologie Physico-Chimique
13 rue Pierre et Marie Curie
75005 Paris - France
Tel : +33 (0)1 5841 5099












To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position at the Department of Biochemistry and Redox Biology Center, the University of Nebraska-Lincoln

[limei zhang]

Dear all,
I'd like to draw your attention to the opening for a postdoc position in my 
group at the Department of Biochemistry and Redox Biology Center, University of 
Nebraska-Lincoln (Lincoln, NE, USA). The research for the postdoc position 
focus on the roles and underlying mechanism of metalloproteins in redox stress 
response and antibiotic resistance. Please click the link below for more 
information.
https://jobrxiv.org/job/university-of-nebraska-lincoln-27778-postdoc-in-structural-biology-and-redox-biochemistry/
[https://jobrxiv.org/wp-content/uploads/2021/03/Link-preview-image-09-03-2021.png]
Postdoc in Structural Biology and Redox Biochemistry - 
jobRxiv
A postdoc position is available in Dr. Limei Zhang’s group at the Department of 
Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, for 
highly motivated candidates who are interested in structural biology, redox 
biology and/or infectious disease.
jobrxiv.org
To apply or for specific questions, please contact me at limei.zh...@unl.edu.
Thanks for your attention,
Limei Zhang
Associate Professor
Department of Biochemistry/Redox Biology Center
University of Nebraska-Lincoln
Email: limei.zh...@unl.edu
http://biochem.unl.edu/limei-zhang





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position: Cryo-EM and Crystallography of functional RNA/protein complexes

[Yunsun Nam]

Postdoctoral Research Fellow position: 
Biochemistry and Structural Biology of Functional RNAs and RNA/protein Complexes

A postdoctoral research position is available in the laboratory of Yunsun Nam, 
in the Department of Biochemistry at University of Texas Southwestern Medical 
Center in Dallas to study the mechanisms of post-transcriptional gene 
regulation. Our laboratory works on exciting projects dissecting the molecular 
mechanisms underlying RNA-mediated gene regulation. The goal is to determine 
how macromolecular recognition and enzymatic regulation are accomplished for 
many RNA-protein complexes, using biochemistry, structural methods, and 
molecular/cellular biology. The functional noncoding RNAs and RNA/protein 
complexes we study are relevant for normal development as well as diseases such 
as cancer, making our mechanistic work valuable for therapeutics research. 
Postdoctoral scholars will have many opportunities to learn the newest methods 
in protein and nucleic acid biochemistry and biophysics, in addition to working 
in an exciting, fast-evolving field in biomedical sciences. We use various 
approaches, including cryo-electron microscopy (cryo-EM), X-ray 
crystallography, NMR spectroscopy, molecular biology, nucleic acid and protein 
biochemistry, genomics with next-generation sequencing, high-throughput 
screening for drug discovery, and mammalian cell-based studies. The 
postdoctoral fellow will have ready access to the top of the line equipment and 
resources necessary for the above approaches. Information on the UT 
Southwestern postdoctoral training program and benefits can be found in the 
Postdoc Handbook on their website. 

Candidates must hold a Ph.D. and/or M.D. degree. Experience in biochemistry 
and/or structural biology leading to publication in peer-reviewed journals is 
recommended. Interested individuals should send a CV, a statement of interests, 
and a list of three references as a single pdf file to:

Yunsun Nam, Ph.D. 
Associate Professor
UT Southwestern Medical Center
5323 Harry Hines Blvd. 
Dallas, TX 75390-9038
yunsun@utsouthwestern.edu
Lab Website: www.ynamlab.org

UT Southwestern Medical Center is committed to an educational and working 
environment that provides equal opportunity to all members of the University 
community. As an equal opportunity employer, UT Southwestern prohibits unlawful 
discrimination, including discrimination on the basis of race, color, religion, 
national origin, sex, sexual orientation, gender identity, gender expression, 
age, disability, genetic information, citizenship status, or veteran status.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position at Fox Chase Cancer Center, Philadelphia, USA

[Wu, Jinhua]

Happy New Year Everyone! We are recruiting a postdoctoral associate as 
described below.


A postdoctoral position is available immediately at Fox Chase Cancer Center 
(Philadelphia, PA) for a highly-motivated individual in the field of structural 
biology and protein biochemistry.

Our lab aims to understand the molecular mechanisms underlying the signaling 
events mediated by integrins, small GTPases, as well as kinases, which have 
strong implications in cancer progression, metastasis and other human diseases, 
and to translate these knowledge into inhibitor/drug discovery. For this, we 
employ a combination of techniques including protein crystallography, electron 
microscopy, binding kinetics analysis, functional assays in mammalian cells, 
and genetic analysis. Our study will facilitate efforts to discover novel 
targets for therapeutic intervention of immune system disorders, tumor 
metastasis, and many other related diseases. 
(https://www.foxchase.org/people/jinhua-wu.)

The candidate should hold a Ph.D. degree with strong experience in X-ray 
crystallography, protein biochemistry, and molecular biology. Prior experiences 
in mammalian cell culture, flow cytometry, drug screen, and cancer biology, are 
desired but not required. Fox Chase Cancer Center is a long-standing 
NCI-designated Comprehensive Cancer Center with multidisciplinary research 
interests from basic biological sciences to drug development and clinical 
studies. The institute is located in a quiet, safe, friendly neighborhood at 
the outskirts of the city. It is one of the top-ranked work places for visiting 
scholars and postdoctoral researchers. We also offer an outstanding research 
environment and strong support for the career development for our scientists.

Please send a cover letter describing previous research experience and future 
plans, a current CV, a copy of graduate transcript, and a list of three 
references to: jinhua...@fccc.edu.

Selected Recent Publications

Zhang P, Azizi L, Kukkurainen S, Gao T, Baikoghli M, Jacquier MC, Sun Y, Maatta 
JAE, Cheng RH, Wehrle-Haller B, Hytonen VP, Wu J. Crystal structure of the 
FERM-folded talin head reveals the determinants for integrin binding. Proc Natl 
Acad Sci U S A. 2020. Epub 2020/12/09. doi: 10.1073/pnas.2014583117. PubMed 
PMID: 33288722.

Kukkurainen S, Azizi L, Zhang P, Jacquier MC, Baikoghli M, von Essen M, 
Tuukkanen A, Laitaoja M, Liu X, Rahikainen R, Orlowski A, Janis J, Maatta JAE, 
Varjosalo M, Vattulainen I, Rog T, Svergun D, Cheng RH, Wu J, Hytonen VP, 
Wehrle-Haller B. The F1 loop of the talin head domain acts as a gatekeeper in 
integrin activation and clustering. J Cell Sci. 2020;133(19). Epub 2020/10/14. 
doi: 10.1242/jcs.239202. PubMed PMID: 33046605.

Cho EA, Zhang P, Kumar V, Kavalchuk M, Zhang H, Huang Q, Duncan JS, Wu J. 
Phosphorylation of RIAM by Src Promotes Integrin Activation by Unmasking the PH 
Domain of RIAM. Structure. 2020. Epub 2020/12/05. doi: 
10.1016/j.str.2020.11.011. PubMed PMID: 33275877.

Chang YC, Su W, Cho EA, Zhang H, Huang Q, Philips MR, Wu J. Molecular basis for 
autoinhibition of RIAM regulated by FAK in integrin activation. Proc Natl Acad 
Sci U S A. 2019;116(9):3524-9. doi: 10.1073/pnas.1818880116. PubMed PMID: 
30733287; PMCID: PMC6397589.


Best wishes,
Jinhua
—
Jinhua Wu Ph.D.
Associate Professor
Molecular Therapeutics Program
Fox Chase Cancer Center W410
333 Cottman Ave.
Philadelphia, PA 19111
215-728-2867 (office)
215-728-3616 (fax)





This electronic message is intended to be for the use of the named recipient, 
and may contain information that is confidential or privileged. This 
communication may contain protected health information (PHI) that is legally 
protected from inappropriate disclosure by the Privacy Standards of the Health 
Insurance Portability and Accountability Act (HIPAA) and relevant Pennsylvania 
Laws. You can direct questions concerning PHI or HIPAA to the Corporate 
Compliance and Privacy Officer at (215) 707-5605. If you are not the intended 
recipient, please note that any dissemination, distribution or copying of this 
communication is strictly prohibited. If you have received this message in 
error, you should notify the sender immediately by telephone or by return 
e-mail and delete and destroy all copies of this message.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position at Caltech

The Hoelz laboratory at the California Institute of Technology seeks to recruit 
an outstanding postdoctoral scientists in structural cell biology. Our 
laboratory focuses on the structure-function relationships of the nuclear pore 
complex and associated nucleocytoplasmic transport machinery.

This position requires a recent Ph.D. degree in biochemistry/biophysics with a 
strong background in biochemistry, x-ray crystallography, or cryo-electron 
microscopy/tomography. The successful applicant should be a highly motivated 
individual with good organizational, communication, and interpersonal skills. 

The laboratory is well-funded and equipped with modern biophysical 
instrumentation. Importantly, Caltech has an exceptional infrastructure for 
structural biology, including access to a high intensity, completely automated, 
state-of-the-art crystallography beamline at the Stanford Synchrotron Radiation 
Lightsource (SSRL), as well as an excellent cryo-electron microscopy facility 
with access to FEI Arctica and Titan Krios microscopes equipped with Gatan K3 
cameras. 

The position is available immediately and funded for 3+ years. Depending on 
performance, the position can be extended for additional years.

To apply, please send your CV, a statement of research interests, and the names 
and contact information of at least two references to André Hoelz 
(ho...@caltech.edu).

Selected Recent Publications

Bley, C.J., Nie, S., Mobbs, G.W., Petrovic, S., Gres, A.T., Liu, X., Mukherjee, 
S., Harvey, S., Huber, F.M., Lin, D.H., Brown, B., Tang, A.W., Rundlet, E.J., 
Correia, A.R., Chen, S., Regmi,  S.G., Dasso, M., Patke, A., Palazzo, A.F., 
Kossiakoff,  A.A., Hoelz, A. (2021). BioRxiv 
(https://doi.org/10.1101/2021.10.26.465790).

Petrovic, S., Samanta, D., Perriches, T., Bley, C.J., Thierbach, K., Brown, B., 
Nie, S., Mobbs, G.W., Liu, X., Hoelz, A. (2021). Architecture of the 
linker-scaffold in the nuclear pore. BioRxiv 
(https://doi.org/10.1101/2021.10.26.465796).

Lin, D. H., Hoelz, A. (2019). The structure of the nuclear pore complex (an 
update). Annu. Rev. Biochem. 88, 725-783. 

Lin, D. H., Correia, A.C., Cai, S.W., Huber, F.M. Jette, C.A., Hoelz, A.* 
(2018). Structural and functional analysis of mRNA export regulation by the 
nuclear pore complex. Nat. Commun., 2319.

Huber, F., Hoelz, A., (2017). Molecular basis for protection of ribosomal 
protein L4 from cellular degradation, Nat. Commun. 8, 14354. 

Lin, D., Stuwe, T., Schilbach, S., Rundlet, E.J., Perriches, T., Mobbs, G., 
Fan, Y., Thierbach, K., Huber, F.M., Collins, L.N., Davenport, A.M., Jeon, 
Y.E., Hoelz, A. (2016). Architecture of the symmetric core of the nuclear pore, 
Science 352, aaf1015. [Cover]

Stuwe, T., Bley, C.J., Thierbach, K., Petrovic, S., Schilbach, S., Mayo, D.J., 
Perriches, T., Rundlet, E.J., Jeon, Y.J., Collins, L.N., Huber, F.M., Lin, 
D.H., Paduch, M., Koide, A., Lu, V., Fischer, J., Hurt, E., Koide, S., 
Kossiakoff, A., Hoelz, A.* (2015). Architecture of the fungal nuclear pore 
inner ring complex, Science 350, 56-64.

Stuwe, T., Correia, A., Lin, D. H., Paduch, M., Lu, V. T., Kossiakoff, A. A., 
Hoelz, A.* (2015). Architecture of the nuclear pore complex coat. Science 347, 
1148-1152.   

Hoelz, A., Debler, E.W., Blobel, G. (2011). Structure of the Nuclear Pore 
Complex, Annu. Rev. Biochem. 80, 613-643.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position - Pseudokinase mechanisms

[Yogesh Kulathu (Staff)]

Dear all

The Kulathu Lab at the MRC PPU, University of Dundee is looking to hire a 
postdoc with strong expertise in biochemistry and structural biology to address 
exciting questions about how the pseudokinases IRAK2 and IRAK3 regulate innate 
immune signalling.

The innate immune response is the first line of defence against bacteria, 
viruses and parasites. When innate immune receptors are triggered, the IRAK 
kinases are activated to trigger a signalling cascade that culminates in the 
expression and secretion of cytokines that shape the immune response to 
invading pathogens. There are 4 IRAK kinases expressed in humans, two of which 
(IRAK2 and IRAK3) lack key catalytic residues and are therefore dead kinases or 
pseudo-kinases. The aim of this project will be to understand the molecular 
mechanisms by which these dead kinases regulate immune signalling. This project 
will build on recently published work1 and utilize protein biochemistry, 
cryo-electron microscopy, X-ray crystallography to define how IRAK kinases are 
activated and regulated. This project has the potential to reveal fundamental 
principles underlying the activation and regulation of innate immune 
signalling, and reveal how they could be modulated to treat inflammatory 
diseases such as arthritis, artherosclerosis, systemic lupus erythematosus and 
psoriasis. This work will be a collaborative project with Sir Philip Cohen.
1Lange et al. Structure 2020. DOI: https://doi.org/10.1016/j.str.2020.11.004

Who we're looking for:
We are looking for a talented, motivated individual with a PhD (or nearing 
completion of your PhD) in Biochemistry, Structural biology or a related field. 
Candidates will be expected to have expertise in the following areas:
· Recombinant protein expression and purification
· In vitro reconstitution and characterization of multiprotein complexes
· Biochemistry, enzyme kinetics
· Structural biology
You will have a track record of research productivity and have demonstrated an 
ability to work independently, enthusiasm for research and excellent 
communication skills. It is expected that the candidate will develop and apply 
a broad range of techniques to pursue the research objectives.

To apply on-line, please visit 
www.dundee.ac.uk/jobs (please quote reference 
number SLSC0989) and submit a single PDF file that contains:
· A curriculum vitae. Please include list of publications and 
submissions to Biorxiv with a brief description of your contribution to the 
work.
· A cover letter that outlines your current research, research 
interests, career goals and a brief summary highlighting your expertise in 
biochemistry, structure-function analyses and/or cell biology.
Informal enquiries may be directed to Yogesh Kulathu 
ykula...@dundee.ac.uk.

As an internationally diverse institution, we welcome job applicants from all 
countries and nationalities. The School of Life Sciences is proud to employ 
staff from over 40 different nations and provides a dynamic, multi-national, 
collegiate and diverse environment with state-of-the-art laboratory, technology 
and teaching facilities. See here for more details on this position and working 
at the University of Dundee: 
https://www.ppu.mrc.ac.uk/careers/recruitment/postdoctoral-research-assistant-slsc0989

Thank you
Yogesh
--

Yogesh Kulathu (he/him)
MRC Investigator
MRC Protein Phosphorylation & Ubiquitylation Unit
The Sir James Black Centre
School of Life Sciences,
University of Dundee
Dundee DD1 5EH, Scotland, UK.

ykula...@dundee.ac.uk
Kulathu Lab Website
Twitter: @YKulathu




The University of Dundee is a registered Scottish Charity, No: SC015096



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position for time-resolved crystallography at NSLS-II

[Martin Fuchs]

Dear all,

We are looking for a postdoc to join our time-resolved synchrotron 
crystallography project at the Center for BioMolecular Structure at National 
Synchrotron Light Source-II (NSLS-II).

Our program operates two MX beamlines, a life-sciences scattering beamline, and 
a cryo-EM facility. The project will establish room temperature- and 
time-resolved serial synchrotron crystallography at the FMX beamline, based on 
our microbeam- and serial crystallography protocols. We collaborate with our 
colleagues at the Brookhaven National Lab Biology department to study dynamic 
processes in proteins such as enzymes.

More about the position, and how to apply:
https://jobs.bnl.gov/job/upton/postdoctoral-research-associate-macromolecular-crystallography/3437/11526913744

We're looking forward to hearing from you. If you have questions please get in 
touch.

Best wishes,
Martin


---

Martin Fuchs
--
Photon Sciences, Mail Stop 745
Brookhaven National Laboratory
Upton, NY 11973, USA
Mail: mfu...@bnl.gov
Phone: +1 631 344 8890



FMX beamline at NSLS-II
https://www.bnl.gov/ps/beamlines/beamline.php?r=17-ID-2

Center for Biomolecular Structure at NSLS-II
https://www.bnl.gov/ps/lifesciences/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position in cryo-EM and crystallography of ion channels in Vancouver, Canada

[Filip Van Petegem]

Dear colleagues,

A postdoc position is available immediately at the University of British
Columbia.


The project combines X-ray crystallography, cryo-EM, and electrophysiology.
Our lab has steady access to the in-house X-ray and cryo-EM facilities:



- Microscopes: 300kV Titan Krios with Falcon IV detector and Selectris
Energy filter.   A 200kV Glacios (Falcon III detector) is available for
prescreening grids


- X-ray equipment in the lab includes Mosquito and Dragonfly robotics, and
we have regular access to an in-house X-ray diffractor (Rigaku Micromax-007
HF with Saturn 744+ CCD detector) and various synchrotron beamlines



Minimum requirements for applicants include a PhD in Biochemistry or a
related discipline with extensive experience in either X-ray
crystallography or cryo-EM, as well as protein expression and
purification.  Direct experience with membrane proteins is an additional
plus.



The lab values diversity and inclusivity, and applicants from all
backgrounds are encouraged to apply. This is an opportunity for people with
structural biology expertise to learn electrophysiological methods.



Recent work from the lab includes an investigation of how Ryanodine
Receptors are modulated by small molecules, disease mutations, and
post-translational modification, using cryo-EM, X-ray crystallography,
planar lipid bilayer electrophysiology, and enzyme kinetics.

Woll et al (2021) *Nature Comm.* 12:807

Ma et al (2020) *Nat Chem Biol*. 16,1246-1254

Haji-Ghassemi et al (2019) *Molecular Cell* 75,1-14



For more information on recent work, see http://crg.ubc.ca/VanPetegem/



The lab is housed within the Life Sciences Centre at UBC (lsi.ubc.ca),
located on the Point Grey campus in Vancouver.



Interested candidates should send a CV, along with names and contact
details for 3 references to *filip.vanpete...@gmail.com
*.




-- 
Filip Van Petegem, PhD
Professor, Dept. of Biochemistry and Molecular Biology
The University of British Columbia
2350 Health Sciences Mall - Rm 2.356
Vancouver, V6T 1Z3

phone: +1 604 827 4267
email: filip.vanpete...@gmail.com
http://crg.ubc.ca/VanPetegem/

Twitter: @FilipPetegem



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position in Structural Biology of Membrane Repair

[Oliver Daumke]

A two-year PostDoc position according to German pay grade 13, with the 
possibility of extension, is available from February 2022 in the group 
of Oliver Daumke at the Max-Delbrück-Center in Berlin in the area of 
‘Structural biology of membrane repair’, with a focus on cryoEM studies. 
The Daumke group studies structure and function of membrane-associated 
proteins, see Ganichkin et al, PNAS 2021, Grunwald et al, Nat Comm 2020, 
Faelber et al, Nature 2019, Turco et al, Mol Cell 2019 for recent examples.


The MDC offers a highly vibrant scientific environment, with 
state-of-the-art infrastructure for structural biology, including cryoEM 
(in house TALOS L120C screening microscope and Titan Krios, Aquilos 
FIB-SEM, Leica CLEM within a cryoEM facility on our campus) and 
crystallography (pipetting robots, plate hotels, regular access to BESSY 
and DESY synchrotrons). Numerous interactions with other structural 
biology, cell biology and biophysical groups on our Campus in 
Berlin-Buch are available.


The applicant should hold a PhD in biochemistry/structural biology or 
closely related areas. Previous experience in structure biology, in 
particular cryo-EM (single particle and/or cryo electron tomography) is 
desirable.Experience in protein expression systems and microscopy is a 
plus.


For application, please use our online portal and submit your 
application as one pdf file (5 MB max.), including a motivation letter 
and a CV with a publication list. Application deadline: November 30, 2021.


https://recruitingapp-5471.de.umantis.com/Vacancies/599/Application/CheckLogin/2?lang=eng 



Please contact Oliver Daumke (oliver.dau...@mdc-berlin.de 
) for further inquiries.





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


smime.p7s
Description: S/MIME Cryptographic Signature

[ccp4bb] postdoc position cryo-EM available (Bajic lab, New York)

[Goran Bajic]

We are looking for a postdoctoral candidate with experience in single-particle 
cryo-EM and willingness to learn virology and immunology. 
Ph.D. in Biochemistry, Biophysics or a related discipline is required. 
Tomography (cryo-ET) experience is an asset but not a pre-requisite.
The Bajic lab uses structural biology (cryo-EM and X-ray crystallography), 
virology and immunology approaches to answer fundamental, mechanistic questions 
in immune responses to viral pathogens. The
position is for a postdoctoral trainee interested in host immune recognition 
mechanisms of influenza, SARS-CoV-2, Chikungunya, and other viruses.

The position is available as soon as possible, but the start date is negotiable.

Lab Website: https://www.bajiclab.org/ 
Twitter: @gogo_science

Find out more about our department: 
https://icahn.mssm.edu/about/departments/microbiology 


To apply, send your C.V., cover letter, and contact information for 3 
references directly to Dr. Bajic.


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in structural analysis of unconventional trypanosome kinetochores, University of Oxford

[Bungo Akiyoshi]

Dear Colleagues,

A postdoc position is available in my group at the Department of Biochemistry, 
University of Oxford.
We are seeking to appoint a motivated person with PhD training in structural 
biology to reveal the structure and function of unconventional kinetoplastid 
kinetochore proteins.

Although it was widely believed that all eukaryotes would have a conserved set 
of kinetochore proteins, we identified more than 20 uncharacterized kinetochore 
proteins (named KKT1–25) in Trypanosoma brucei and discovered that they 
constitute unconventional kinetochores specific to kinetoplastids, a group of 
evolutionarily-divergent eukaryotes (Akiyoshi and Gull, Cell 2014, Marcianò et 
al, Journal of Cell Biology 2021, Tromer et al., Open Biology 2021, Ludzia et 
al., Structure 2021). We are currently characterizing these KKT proteins using 
various techniques including cell biology, bioinformatics, super-resolution 
microscopy, biochemistry, biophysics, and structural biology (X-ray 
crystallography, NMR, electron tomography, and cryoEM/ET).

For more information, please click on the link below:
https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10_internal_external=E_display_in_irish=N_process_type=_applicant_no=_form_profile_detail=_display_apply_ind=Y_refresh_search=Y_recruitment_id=153946

Please contact me if you are interested in this position.

Best wishes,
Bungo

--
Bungo Akiyoshi, PhD
Wellcome Trust Senior Research Fellow, EMBO YIP
Department of Biochemistry, University of Oxford
https://bungoakiyoshi.com/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position available in the lab of Prof. Eddy Arnold (Rutgers University, NJ, USA)

[F. Xavier Ruiz]

Dear All,

We have an immediate opening for a skilled post-doctoral researcher in the 
laboratory of Prof. Eddy Arnold at Rutgers University (NJ, USA). The aim of the 
project is to study the structure and function of human viral proteins, mainly 
polymerases from HIV-1, SARS-CoV-2 and other RNA viruses posing a pandemic 
threat, through X-ray crystallography and cryo-electron microscopy.

For more information about the position, please see the full advert: 
https://jobs.rutgers.edu/postings/145198 
Interested candidates should apply via the above link. For informal inquiries, 
please feel free to contact me directly.

Best wishes,

F. Xavier RUIZ
Assistant Research Professor
Arnold Laboratory Center for Advanced Biotechnology and Medicine Rutgers 
University
https://cabm.rutgers.edu/research/arnold-lab



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position Oxford Univ - Structural and Chemical Biology of E3 Ligases

[Alex Bullock]

A postdoc position is available in the group of Alex Bullock, University of 
Oxford, to study the structural and chemical biology of E3 Ligases as part of 
the EU-funded "EUbOpen" consortium, with funding until 30 April 2025. The 
project will support the next generation of PROTACs/molecular glues for 
targeted protein degradation.
Nature Reviews Drug Discovery volume 18, pages 949-963 (2019)
https://www.nature.com/articles/s41573-019-0047-y

The postholder will optimise purification and crystallisation systems for human 
Cullin-RING E3 ligase substrate adaptor proteins, solve their structures and 
study their interactions with substrate proteins, peptides and low molecular 
weight compounds. The post will involve significant collaborative teamwork 
internally, as well as with external academic and industry partners.

Applications close at noon 10 November 2021. Full details are available here:
Job Details 
(corehr.com)

Informal enquires can be sent to 
alex.bull...@cmd.ox.ac.uk

https://www.cmd.ox.ac.uk/team/alex-bullock
https://www.cmd.ox.ac.uk/research/growth-factor-signalling-and-ubiquitination





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position @ Max Planck Institute for Biophysical Chemistry, Goettingen

[Sonja Lorenz]

Dear colleagues,

my group has an exciting opening for a postdoc position to explore the biology 
of ubiquitin ligase complexes. 
For details, please see:
https://www.mpibpc.mpg.de/18138284/26-21-Postdoc?c=82987 


If you could forward this link to suitable candidates, I would be very grateful.
Thank you and best wishes,

Sonja Lorenz, PhD
Research Group "Ubiquitin Signaling Specificity”
Max Planck Institute for Biophysical Chemistry
Am Fassberg 11
37077 Goettingen
Germany
Twitter@SLorenzLab
https://www.mpibpc.mpg.de/lorenz 


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position protein crystallography, Heinrich-Heine-University, Düsseldorf, Germany

[Astrid Port]

Postdoc position protein crystallography, Heinrich-Heine-University, 
Düsseldorf, Germany


The Center for Structural Studies (CSS) is a central scientific research 
and service facility of the Faculty of Mathematics and Natural Science 
at the Heinrich-Heine-University Düsseldorf (www.css.hhu.de). The CSS 
aims for scientific tasks within all areas of structure-supplying 
methods at an atomic level. The CSS provides all steps as full-service 
as well as access to our infrastructure and scientific support for the 
individual experiments of all members of the HHU and external users.


In particular:
•	X-ray diffraction analysis and structure determination (MX) of 
proteins (in house and at synchrotrons)
•	Small-Angle-X-ray-Scattering-Analysis (SAXS) of proteins and all kinds 
of complexes thereof (in house and at synchrotrons)

•   Molecular Modelling and Simulation for macro- and micromolecules

In support of the MX unit we offer a postdoc position within a BMBF 
(Federal Ministry of Education and Research) founded project for an 
experienced person (100 %, EG 13 TV-L/TVöD-Bund) for 2 years.


Your Qualifications
•	degree in Biochemistry, Biology or a related field and a PhD ideally 
in X-ray protein

crystallography
•   ideally several PDB-depositions and related publications
•	good work experience in protein biochemistry, crystallization and 
X-ray crystallography
•	good knowledge of software packages employed in protein 
crystallography (esp. XDS, CCP4, coot) is a must
•	good communication skills and like to work in a multi-disciplinary 
team


Key Responsibilities
•   all types of crystallographic activities, including:
•   planning and performing crystallization experiments
•	collecting X-ray diffraction data (in-house generator and synchrotron 
beamlines)

•   processing diffraction data, including phasing (mainly MR)
•   refining protein structures following the quality criteria
•   presenting the results

According to the applicant’s personal qualification, employment will be 
based on EG 13 TV-L / EG 13 TVöD-Bund. Qualified candidates should send 
their complete application (cover letter, curriculum vitae, contact info 
of two references, certificates) until 25.10.2021 by e-mail (one single 
pdf-file <5MB) to c...@hhu.de.


We are looking forward to your joining of our team!




--
Heinrich-Heine-Universität
Center for Structural Studies (CSS)
Universitätsstr. 1
40225 Düsseldorf
Germany
www.css.hhu.de



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc position at the SGC-TORONTO, University of Toronto

[Levon Halabelian]

 A PostDoc position is immediately available at the SGC, University of
Toronto. Details can be found in the following link:
https://www.thesgc.org/careers/toronto/postdoctoral-position-%E2%80%93-limited-term

Regards,
Levon



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in computational structural biology at St. Jude

[Marcus Fischer]

We are recruiting a postdoc for a computational structural biology project
that investigates the role of water networks at protein ligand interfaces
with a view towards ligand discovery. The position is available immediately
and NIH funded for 5 years.



We are looking for highly motivated candidates with curiosity and skills to
reveal hidden factors that contribute to protein-ligand binding and
leverage this information for ligand discovery. As this project integrates
experimental and computational data it will require both a solid background
in structural biology and significant computational skills for custom data
analysis and automation. The project is embedded into a dynamic lab that
has strong expertise in modulating protein conformational ensembles with
ligands and temperature (see references below).



The project is housed in the Department of Chemical Biology and Therapeutics
,
and Structural Biology

at
St. Jude Children’s Research Hospital. It builds on strong investments into
a world-class infrastructure in structural and chemical biology. This is an
exciting time to join us and build a career while living in an affordable
city. This postdoc position is NIH funded for 5 years.



Please direct your questions and application package including a cover
letter, current CV, and 3 letters of reference to: Dr. Marcus Fischer (
marcus.fisc...@stjude.org).



Relevant papers include:

   - Bradford et al. (2021). Temperature artifacts in protein structures
   bias ligand-binding predictions. *Chemical Science*.
   DOI: 10.1039/D1SC02751D
   - Fischer (2021). Macromolecular room temperature crystallography. *Q
   Rev Biophys* 54. E1
   - Darby et al. (2019). Water Networks Can Determine the Affinity of
   Ligand Binding to Proteins. *JACS* 141, 15818-26.
   - Balius et al. (2017). Testing inhomogeneous solvation theory in
   structure-based ligand discovery. *PNAS* E6839-46.
   - Fischer et al. (2015). One crystal, two temperatures: cryocooling
   penalties alter ligand binding to transient protein sites. *Chembiochem*
1560-64.
   - Fischer et al. (2014). Incorporation of protein flexibility &
   conformational energy penalties in docking screens to improve ligand
   discovery. *Nature Chemistry* 6, 575-83.



More info at:

https://www.stjude.org/fischer
Minimum Education

   - PhD in structural biology or related field

Minimum Experience

   - High proficiency in coding incl Python
   - Interest in dynamic aspects of structural biology including protein
   flexibility and hydration

Optional requirements:

   - Hands-on molecular biology and crystallography experience


https://postdoc-stjude.icims.com/jobs/8641/postdoctoral-research-assoc/job



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at Rice Unversity, Houston

[Yang Gao]

Dear All,

A postdoctoral position is available in Dr. Yang Gao’s Lab 
(http://yanggaolab.blogs.rice.edu/) at Rice University, Houston, TX. Our lab 
studies enzymes and motors in DNA replication and repair. We combined 
biochemical, biophysical techniques with cryo-electron microscope and 
crystallography to investigate how the genomic DNA is replicated and 
maintained. Previous experiences with protein cloning, expression, and 
purifications are needed. Experiences in crystallography and cryo-EM are a plus 
but not stickily required. Candidates with experience in biochemical 
reconstitution and characterizations of large enzyme complexes are more than 
welcome.

Interested candidates please contact Yang at y...@rice.edu for details. 

Best
Yang 

Yang Gao
Assist. Prof., CPRIT Scholar
Department of BioSciences
Rice University



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in peptide-based PROTACs

[Marcus Hartmann]

Dear BB,

we have a Postdoc opening in our group at the Interfaculty Institute of 
Biochemistry and the Max Planck Institute for Developmental Biology in 
Tübingen, Germany.

We are looking for someone who can't wait to develop peptide-based PROTACs as 
next-generation therapeutics with us. The candidate does not need to be an 
expert in crystallography but have a solid understanding of structural biology 
in general.

Please find more details here:
http://eb.mpg.de/fileadmin/uploads/PostDoc_peptidic_PROTACs.pdf

Best wishes,
Marcus


--
Dr. Marcus Hartmann
Max Planck Institute for Developmental Biology
Max-Planck-Ring 5, 72076 Tübingen, Germany. Phone: +49 (0)7071 601 323
http://www.eb.mpg.de/protein-evolution/marcus-hartmann/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position

[Smita]

Oklahoma State University-Main Campus: College of Arts & Sciences: Department 
of Chemistry


The Department of Chemistry at Oklahoma State University invites applications 
for a Postdoctoral Fellow in Protein NMR in Mohanty lab.  The PI desires an 
applicant that can lead an independent project focusing on protein 
structure-function studies using high-resolution solution NMR, would be able to 
conduct molecular biology (sub-cloning and mutagenesis) work along with 
over-expression and purification of recombinant proteins, will provide updates 
on research progress during weekly group meetings, write scientific manuscripts 
for peer reviewed journals, disseminate research at national conferences 
(oral/poster presentations) and assist the PI with various research related 
work.

Minimum qualifications are a PhD in chemistry or biochemistry or biophysics 
along with familiarity with very good knowledge of protein NMR and 3D structure 
calculation, and other biophysical and computational techniques.  A record of 
scientific output (peer-reviewed publications) and strong writing and 
communications skills are also required.

For full consideration, please apply at https://apply.interfolio.com/93521 and 
submit curriculum vitae and contact information by October 15, 2021. 
Applications will continue to be accepted until the position has been filled.

Oklahoma State University, as an equal opportunity employer, complies with all 
applicable federal and state laws regarding non-discrimination and affirmative 
action.  Oklahoma State University is committed to a policy of equal 
opportunity for all individuals and does not discriminate based on race, 
religion, age, sex, color, national origin, marital status, sexual orientation, 
gender identity/expression, disability, or veteran status with regard to 
employment, educational programs and activities, and/or admissions.  For more 
information, visit https:///eeo.okstate.edu.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in Bergen (Norway)

[Petri Kursula]

Hi,

we are looking for a postdoc in our project, focusing on a multidisciplinary 
approach towards formation, structure, and dynamics in proteolipid multilayer 
structures, such as seen in vertebrate myelin. As we are in the near future 
hiring several people, we are looking for an optimal combination of expertise, 
and various backgrounds related to biophysics and structural biology will be 
considered. 

The announcement, with a deadline on Oct 10th, can be found at:
https://www.jobbnorge.no/en/available-jobs/job/212348/postdoctoral-research-fellow-3-years
 


All applications must be done through the online portal (please do attach a CV 
even though the system does not strictly require it). While applications by 
email will not be considered, informal queries are welcome.

Best regards,
Petri

Petri Kursula
--
Professor 
--
Department of Biomedicine
University of Bergen, Norway
https://link.uib.no/petri
petri.kurs...@uib.no
--
Faculty of Biochemistry and Molecular Medicine
Biocenter Oulu
University of Oulu, Finland
--










To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at University of Colorado School of Medicine

[Zhao, Rui]

To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


postdoc position.pdf
Description: postdoc position.pdf

[ccp4bb] Postdoc Position at a DESY, Deutsches Elektronen-Synchrotron, Hamburg in structural biology of microbial and antimicrobial amyloids and protein fibrils

[Landau Meytal]

 Dear all,
We have a postdoctoral fellow position opening for a highly motivated scientist 
who is interested in ever-growing, multidisciplinary, challenging, and fun 
research for applications in biomedicine, drug development, and nanotechnology.
The project will investigate mechanisms governing virulence and antibacterial 
properties of protein fibrils in infectious and aggregation diseases. The 
research methods include single particle cryoEM reconstruction, cryoEM 
tomography, x-ray crystallography, correlative light and electron microscopy, 
artificial membrane systems (supported lipid bilayers, liposomes), and live 
cell microscopy to study toxicity mechanisms of fibrils on bacteria and 
mammalian cells and within microbial biofilms.
For more information about the research and publications: 
 https://mlandau.net.technion.ac.il/
The project will be carried out at the CSSB, 
Center for Structural Systems Biology, hosted by the Sondermann 
group,
 and in close collaboration and supervision by the Landau group at Technion – 
Israel Institute of Technology. The project will enjoy the state-of-the-art 
high-end facilities at the 
CSSB within the thriving 
research environment for structural biology on the DESY campus.
 Profile

  *   •   Candidate with PhD in Chemistry, Biology, Physics, Bio-materials, 
Bio-technological and Bio-medical Sciences and Engineering, and related fields.
  *   •   Fluent in English (both written and oral).
  *   •   High motivation.
  *   •   Ability to work in a team while maintaining independency.
  *   •   Multidisciplinarity

 Contact person
Please send your CV and a short letter of intent to Meytal Landau
mlan...@technion.ac.il / 
meytal.lan...@cssb-hamburg.de


—
Meytal Landau, Ph.D.
Associate Professor, Faculty of Biology, Technion, Israel Institute of 
Technology
Visiting Group Leader , EMBL DESY, Hamburg, Germany
E-mail :mlan...@technion.ac.il
www: http://mlandau.net.technion.ac.il/
Tel office/lab:+972-77-8871965/4



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in San Antonio, TX

[Yogesh Gupta]

Dear Colleagues:


My laboratory at the University of Texas Health Science Center at San
Antonio is seeking an enthusiastic Postdoctoral Fellow to work on an
NIH-funded project on SARS-CoV-2 and RNA modification. We will use X-ray
crystallography, cryo-EM, and cell-based methods to address basic
mechanistic questions and develop novel antivirals.


These two papers describe our most recent work on SARS-CoV-2.

Nature Communications. 2021 Jun 2; 12: 3287. PMID: 34078893. DOI:
10.1038/s41467-021-23594-y


Nature Communications. 2020 Jul 24;11(1):3718. PMID: 32709886. DOI:
10.1038/s41467-020-17496-8


Preference will be given to applicants with demonstrated experience in
purification and structural characterization of protein-nucleic acid
complexes by X-ray crystallography with a strong interest in learning
cryo-EM. An ideal candidate should hold (or soon expect to hold) a Ph.D. or
equivalent degree in biochemistry/biophysics/structural biology and have no
more than 3 years of postdoc experience. Salary is competitive and
commensurate with experience.

San Antonio is the nation’s seventh-largest city and is located at the edge
of the beautiful Texas Hill County. San Antonio offers a rich,
multi-cultural community, affordable cost of living, excellent weather, and
a thriving biomedical industry. There is no state income tax in Texas. All
Postdoctoral appointments are designated as security-sensitive positions.
The University of Texas Health Science Center at San Antonio is an Equal
Opportunity/Affirmative Action Employer, including protected veterans and
persons with disabilities.


If interested in applying, please send a short description of your research
accomplishments and a CV with contact information of 3 references to Dr.
Yogesh Gupta (email: gup...@uthscsa.edu).


Yogesh

-- 
Yogesh Gupta, PhD
Assistant Professor of Biochemistry & Structural Biology
Greehey Children's Cancer Research Institute
University of Texas Health Science Center
8403 Floyd Curl Drive, San Antonio, TX, USA 78229
http://ccri.uthscsa.edu/YGupta.html



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position available

[Tobias Beck]

Dear all,

We have an opening for a Postdoc position in my group. The Beck group is
located at the University of Hamburg, with labs well-equipped for nano
chemistry and protein chemistry, and supported with computational
infrastructure for protein design. Moreover, state-of-the-art facilities
for structural characterizations such as PETRA III are close by.

The project will focus on machine learning approaches to guide the redesign
of protein containers. Towards this goal, previous knowledge on protein
assemblies and crystal structures will be be implemented. Identification of
suitable models will be carried out to connect the assemblies to surface
properties of proteins.

The position is available starting on October 1st 2021.

Full details of the post and the applications process are available here:
https://www.uni-hamburg.de/stellenangebote/ausschreibung.html?jobID=8d3f1e2aa16d641f16ae505621127752d3d7ee3e

Link to the group homepage:
https://www.chemie.uni-hamburg.de/institute/pc/arbeitsgruppen/beck.html

Deadline for applications is August 16 2021.

I'd appreciate it if you could pass this announcement on to potentially
interested candidates.
Please contact me for further information or informal inquiries: tobias.beck
@chemie.uni-hamburg.de

Best, Tobias.


Prof. Dr. Tobias Beck
University of Hamburg
Department of Chemistry
Institute of Physical Chemistry
Grindelallee 117
D-20146 Hamburg
Germany

phone:   +49 4042838 8210
fax:   +49 4042838 3462
web:   www.chemie.uni-hamburg.de/institute/pc/arbeitsgruppen/beck/




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position - Understanding antibiotic resistance mechanisms in bacteria

[Klaas Pos]

Dear all,

(On behalf of Prof. Achilleas Frangakis and the EFFORT team)

A postdoc position is available in the group of Prof. Achilleas Frangakis, at 
the Goethe University Frankfurt in Germany, in collaboration with partners of 
the EFFORT consortium, to study efflux pumps using single-particle microscopy 
and cryo-electron tomography.

The mission of the candidate will be to conduct structural and biophysical 
characterization of the RND efflux pumps from pathogens, by using 
single-particle cryo-EM. Additionally, efflux pumps will be characterised in 
their native state using cryo-electron tomography.

Diligent, independent and committed candidates are encouraged to apply. 
Candidates should hold a Ph.D. thesis in molecular biology, biochemistry, 
structural biology or similar disciplines.

The EFFORT consortium is developing a newly discovered class of Efflux Pump 
Inhibitors that can boost the activity of a plethora of antibiotics, making 
them much more effective. EFFORT consortium partners are: medicinal chemistry 
(Pr M. Flipo, U1177), chemical biology of antibiotics (Dr. R C Hartkoorn), 
bacterial efflux pumps and structure/functional biology (Pr. K M. Pos, 
University of Frankfurt, Germany) and cryo-electron tomography (Pr. A. 
Frangakis, University of Frankfurt, Germany). The EFFORT consortium is funded 
by an international – French (ANR) and German (BMBF) call for projects on 
antimicrobial resistance.

Application deadline is August 31st, 2021.

For application and more information, please contact: 
achilleas.franga...@biophysik.org 

Prof. Dr. Achilleas Frangakis
Speaker DFG Research Training Group iMOL
Director Buchmann Institute for Molecular Life Sciences

Buchmann Institute for Molecular Life Sciences (BMLS)
Institute of Biophysics
Goethe University Frankfurt
Max-von-Laue-Str. 15, D-60438 Tel: +49 69 798 46462
GermanyFax: +49 69 798 46465

https://www.bmls.de/Electron_Microscopy/aboutus.html
http://www.biophysik.org/frangakis/
https://imol.uni-frankfurt.de
--

With kind regards,

Martin


Klaas Martinus Pos, Ph.D.
Professor of Membrane Transport Machineries
Institute of Biochemistry N200/1.09
Goethe-University Frankfurt am Main
Max-von-Laue-Str. 9
D-60438 Frankfurt am Main
Germany
Tel: +49-69-798 29251
Fax: +49-69-798 29201
E-Mail: p...@em.uni-frankfurt.de
Website: www.biochem.uni-frankfurt.de




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in Structural Data Science at NNF-CPR at the University of Copenhagen (Taylor and Rasmussen groups)

[Nicholas M I Taylor]

Dear all,

We are looking for a joint postdoc in “Structural Data Science” in the Taylor 
group (Structural Biology of Molecular Machines) and Rasmussen group (Human 
Proteome Variation) at the Novo Nordisk Foundation Center for Protein Research, 
University of Copenhagen. We aim to recruit a scientist with extensive 
experience in data science and/or in silico protein folding or design to help 
pioneer and establish this new research field. The position is for 2 years in 
the first instance and can be renewed for up to 4 years in total, providing a 
unique long-term opportunity to work on an exciting project in a well-equipped 
and supportive environment. The position is available immediately, start date 
will be decided together with the candidate.

The full advert and link to the application form can be found here: 
https://employment.ku.dk/faculty/?show=154452

Please contact me (nicholas.tay...@cpr.ku.dk) 
or Simon (simon.rasmus...@cpr.ku.dk) directly 
for further enquiries.

Application deadline:  16 August 2021, 23.59pm CET

Best wishes,

Nicholas

Nicholas M. I. Taylor, PhD
Associate Professor

University of Copenhagen
Faculty of Health and Medical Sciences
Novo Nordisk Foundation Center for Protein Research
Blegdamsvej 3B, building 6.1
2200 Copenhagen N
Denmark

nicholas.tay...@cpr.ku.dk
http://www.cpr.ku.dk

[cid:image001.gif@01D774DB.CB8DD9D0] [cid:image002.png@01D774DB.CB8DD9D0] 






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in evolutionary biochemistry

[Hochberg, Georg]

Dear colleagues,

The Hochberg group in Marburg is looking for a self-motivated postdoc to study 
how molecular machines become more efficient and complex through evolutionary 
history starting as soon as possible. The position is funded by a Human 
Frontiers Grant for three years to study the evolution of the epsilon 
proteobacterial flagellum as part of a collaboration that includes the Beeby 
lab (cryo-electron tomography, Imperial College, UK), the Pedaci lab (single 
cell force measurements, Montpellier, France) and the Cary lab (Metagenomics, 
New Zealand).

The Hochberg lab uses ancestral sequence reconstruction to bring ancient 
protein complexes back to life and study their properties in the lab. We use a 
broad combination of biophysical techniques to study these ancient complexes, 
but in particular mass photometry, in vitro biochemistry, and cry-electron 
microscopy.  We use this approach to answer fundamental questions about how and 
why biochemical complexity evolved in the very deep past.

The candidate would have the opportunity to develop their own evolutionary 
biochemistry research program alongside the consortium project. In particular, 
we are looking for biochemists that are interested in learning evolutionary 
methods to understand how current macromolecular machines came to be the way 
they are. A willingness to learn phylogenetics and immerse themselves in 
evolutionary thought are essential. Prior knowledge of phylogenetics is not.

Marburg is a charming ancient university town in the middle of Germany, within 
an hour of Frankfurt. Our lab is part of the Max-Planck-Institute for 
Terrestrial Microbiology, which is a world leading address for microbiology and 
synthetic biology. The Max Planck Institutes are Germany’s premier basic 
science institutions. The candidate would be joining this thriving community 
and benefit from the unique, basic science focused environment and excellent 
infrastructure at the Max-Planck-Institutes.

Interested candidates should send an email with their CV, a cover letter 
detailing their motivation and contact information for at least 2 references to 
georg.hochb...@mpi-marbug.mpg.de
More information about our work can be found on or website:
https://www.mpi-marburg.mpg.de/hochberg
and a more detailed description of the project can be found here:
https://www.mpi-marburg.mpg.de/642026/Open-Positions

All the best,
Georg Hochberg




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position (Denmark), Structural biology with a focus on metabolite uptake

[Bjørn Panyella Pedersen]

Dear colleagues,

Please pass this open postodoc position along to anyone who might be 
interested. Thanks!

Deadline is Aug. 15th.


/Bjørn


Link: 
https://www.au.dk/om/stillinger/job/re-advertisement-postdoctoral-position-in-structures-of-metabolite-transporting-membrane-proteins-a/




Postdoctoral position in Structures of Metabolite Transporting Membrane 
Proteins at Aarhus University, Denmark.


The Pedersen group at the Department of Molecular Biology and Genetics, Aarhus 
University, is looking for a highly skilled and motivated postdoc with an 
interest in working on metabolite transporting membrane transporters and 
preferably with a proven track record in the area of structural and/or 
functional analysis of membrane proteins.


Starting date is negotiable. The project is fully funded by the European 
Research Council (ERC) for at least 2 years of employment. An extension is 
possible for up to a total maximum of 4 years of employment as a postdoc.


The position

The position seeks to strengthen ongoing activities in the laboratory of Bjørn 
P. Pedersen on structure, related to the function and mechanism of metabolite 
transporting membrane proteins (pedersenlab.dk). Exact project will be shaped 
out in dialogue with top runners. The laboratory's interest is the interplay 
between structure and function of transmembrane transport processes with a 
focus on metabolite uptake systems.

Structures are determined by cryo-electron microscopy, cryo-electron tomography 
and X-ray diffraction. This also involves expression and purification of 
membrane proteins, or complexes, use of detergents, and nanodiscs, and assays 
of transport in vesicles and in cells. First rate facilities are available in a 
highly cooperative environment. The group is part of the Section of Structural 
Biology at Aarhus University.


The candidate

A successful candidate has a relevant Ph.D. degree and a solid and documented 
background in structural biology, biochemistry and/or biophysics. Experience 
with membrane protein expression and purification is favored, and the candidate 
must demonstrate an ability and interest to work with membrane proteins with a 
structural aim. Applicants should be ambitious, show strong collaborative 
skills, and be able to take initiatives and responsibility within the work 
environment.


The Department of Molecular Biology and Genetics

The Department of Molecular Biology and Genetics is part of the Faculty of 
Natural Sciences, Aarhus University and comprises research within the areas of 
Gene Expression, Molecular Medicine, Structural Biology, Systems Biology and 
Plant Molecular Biology. There are currently 75 full time scientific staff and 
120 PhD students. The department is responsible for two educations: Molecular

Biology and Molecular Medicine with a yearly uptake of 160 students in total. 
Please refer to http://mbg.au.dk/ for further information about The Department 
of Molecular Biology and Genetics and to https://international.au.dk/ for 
information on Aarhus University, respectively.


The successful candidate is offered:

• Access to world-leading research infrastructure.

• A research climate inviting lively, open and critical discussion within and 
across different fields of research.

• A working environment with teamwork, close working relations, network 
activities among young scientists and social activities.

• A workplace characterized by professionalism, equality and a healthy 
work-life balance.


The city

In Aarhus you have easy access to beautiful nature, an exciting culture and 
city life as well as a safe environment for children - a great place for the 
whole family. The city of Aarhus has everything you need within a surprisingly 
small area: exciting national and international jobs, delightful residential 
areas, a rich cultural life, and beautiful surrounding landscape of woods and 
coastline that make Aarhus a wonderful place to live and work. See here for 
further details on the city and the university.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc POSITION

[Greg Snyder]

A postdoctoral position is available immediately to participate in an 
inter-disciplinary research program on biophysical studies of HIV proteins and 
virions at the Institute of Human Virology of University of Maryland School of 
Medicine, Baltimore, MD. We are looking for a highly motivated candidate with a 
strong background in immunology, virology, molecular and cell biology and 
fluorescence microscopy. This position requires experience in immunology 
methods, molecular biology techniques including ELISA, western blotting, PCR, 
transfection and fluorescence microscopy. Central to our laboratory mission is 
an in-depth exploration of the basic mechanisms of humoral response to HIV-1 by 
biophysical methods. We are looking for applicants with a PhD in the field of 
Biochemistry, Molecular biology or Immunology. Experience with fluorescence 
microscopy is a plus. If interested, please contact Krishanu Ray 
.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position: Cryo-EM of Chromatin Complexes, Halic Lab

[Bilokapic, Silvija]

Dear all

Halic lab is looking for highly motivated and enthusiastic postdoctoral 
candidate interested in cryo-EM of chromatin complexes. Strong background in 
molecular cloning, expression, and purification of protein complexes is 
essential. Experience in X-ray crystallography or single particle cryo-EM would 
be a plus but not required.
The successful applicant will join a vibrant community at Department of 
Structural Biology, St. Jude Children's Research Hospital, which provides 
access to state-of-the-art integrated structural approaches comprising 
cryo-electron microscopy and tomography (Titan Krios, Talos Arctica and Talos 
L120C ), X-ray crystallography and biomolecular NMR.

To apply, please send a brief letter of interest, a CV, and the names of three 
references to mario.ha...@stjude.org

@LabHalic



Silvija Bilokapic, PhD

Structural Biology

St. Jude Children’s Research Hospital

262 Danny Thomas Place

Memphis, TN 38105-3678




Email Disclaimer: www.stjude.org/emaildisclaimer
Consultation Disclaimer: www.stjude.org/consultationdisclaimer



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position in RNA-protein structural biology / biochemistry at Univ of Delaware

[Jeffrey Mugridge]

*Postdoctoral Researcher - Structure & Function of RNA-Modifying Enzymes*



The Mugridge lab (mugridgelab.org) in the Department of Chemistry &
Biochemistry  at the University of Delaware is
seeking a postdoctoral researcher to join our team. Our lab is focused on a
mechanistic, structure-level understanding of how cellular RNA-modifying
enzymes control diverse chemical modifications on mRNA and tRNA to affect
RNA structure, processing, translation, and stability, and impact human
disease. *We are looking for an enthusiastic, self-motivated postdoc to
lead a project studying the biochemistry and structural biology of
mRNA-modifying enzymes; this project is fully NIH-funded with the
flexibility to explore different scientific directions and ideas.*



*Preferred Candidates*

We welcome applications from scientists of all backgrounds who are excited
about understanding how protein-protein and protein-RNA interactions
regulate RNA modification and function. The ideal candidate will have a PhD
in biochemistry, structural biology, molecular biology, or a related field,
and have experience with protein expression and purification from bacterial
and eukaryotic expression systems, in vitro and/or cell-based biochemical
assays, and macromolecular structural and/or biophysical techniques.
Applicants with experience studying protein-nucleic acid interactions are
particularly encouraged to apply. The successful applicant will also have a
strong scientific record, excellent communication skills, ability to work
independently and as part of team, and willingness to help mentor junior
scientists.



*Our Lab*

The Mugridge lab combines techniques from biochemistry, structural biology,
biophysics, and chemical biology to determine the structural and molecular
mechanisms that regulate the dynamic chemical modification landscape of
RNA, or the ‘epitranscriptome’. Our lab houses brand new instrumentation
for macromolecular protein function and structure work including an AKTA
Pure 25M FPLC, Agilent 1260 Infinity II bio-inert UHPLC with iQMS mass
spectrometer, Zeiss V20 stereomicroscope and other equipment for protein
crystallography, and new infrastructure to support diverse biochemical and
molecular biology techniques. We are part of a multidisciplinary NIH COBRE
center

at
UD and have ready access to state-of-the-art core facilities including
proteomics/mass spectrometry, protein crystallography, NMR, cell imaging
and microscopy, and DNA/RNA sequencing cores. The University of Delaware is
an R1 research University located in the heart of the mid-Atlantic region,
nearby to Philadelphia, Baltimore, coastal beaches, and within easy driving
distance of NYC and Washington DC.



*Apply or ask!*

To apply, email Jeff (mugri...@udel.edu) a single PDF with a one-page cover
letter and a CV including publication record, brief descriptions of
previous research accomplishments and techniques, and the names and contact
information for three references. Applications will be evaluated on a
rolling basis, so please apply ASAP. If interested, feel free to email Jeff
with any questions!


Job listing at jobRxiv




_
Jeffrey S. Mugridge, PhD
Assistant Professor
Department of Chemistry & Biochemistry
169 Brown Laboratory
University of Delaware
302-831-3578 (office)
mugridgelab.org



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at University of Texas Health, San Antonio, TX, USA

[Yogesh Gupta]

*Postdoctoral Fellow position at UT Health School of Medicine, San Antonio,
Texas*


The laboratory of Dr. Yogesh Gupta (http://ccri.uthscsa.edu/YGupta.html) at
the University of Texas Health at San Antonio is seeking an enthusiastic
Postdoctoral Fellow to study structures and function of RNA modification
and chromatin remodeling complexes. We use structural biology (X-ray, NMR,
cryo-EM) and cell-based methods to address basic mechanistic questions in
viral pathogenesis and pediatric cancers. The laboratory provides a rich
multi-disciplinary training environment and access to cutting-edge
technologies in structural biology and drug development.


Further details of our most recent work can be found here:

1. Nature Communications. 2021 Jun 2; 12: 3287. PMID: 34078893. doi:
10.1038/s41467-021-23594-y


2. Nature Communications. 2020 Jul 24;11(1):3718. PMID: 32709886. doi:
10.1038/s41467-020-17496-8


Preference will be given to applicants with demonstrated experience in
protein purification from insect/mammalian cells and structural
characterization of protein-nucleic acid complexes by X-ray crystallography
or cryo-EM. Candidates are expected to possess strong organizational,
interpersonal skills, and ability to work independently but also
effectively and collaboratively as part of a team. An ideal candidate
should hold (or soon expect to hold) a Ph.D. or equivalent degree in a
related discipline and have no more than 2 years of postdoc experience.


The Greehey Children’s Cancer Research Institute (GCCRI) is a unique
specialized cancer research center focusing on basic and translational
research in childhood cancer and occupies a state-of-the-art 100,000 sq.
foot research facility on the university’s Greehey Academic and Research
Campus. The GCCRI has significant external funding, a large endowment from
the state, and links to philanthropic entities. San Antonio is the nation’s
seventh largest city and is located at the edge of the beautiful Texas Hill
County. San Antonio offers a rich, multi-cultural community, affordable
cost of living, excellent weather and a thriving biomedical industry. There
is no state income tax in Texas. All Postdoctoral appointments are
designated as security sensitive positions. The University of Texas Health
Science Center at San Antonio is an Equal Opportunity/Affirmative Action
Employer including protected veterans and persons with disabilities. Salary
is competitive and commensurate with experience.


If interested in applying, please send a short description of your research
accomplishments and a CV with contact information of 3 references to Dr.
Yogesh Gupta (email: gup...@uthscsa.edu).


Yogesh
-- 
Yogesh Gupta, PhD
Assistant Professor of Biochemistry & Structural Biology
PI, Greehey Children's Cancer Research Institute
University of Texas Health Science Center
8403 Floyd Curl Drive, San Antonio, Texas, USA 78229
http://ccri.uthscsa.edu/YGupta.html



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position at the Francis Crick Institute London

[Katrin Rittinger]

Dear All,

A postdoc position in structural biology is available at the Francis Crick 
Institute, London to study the interaction between the bacterial virulence 
protein SteE from Salmonella and host proteins to understand the mechanism by 
which it interferes with host cell signalling. This is a collaboration with 
Teresa Thurston, Centre for Molecular Bacteriology and Infection, Imperial 
College London and funded by the MRC. The postdoc will be located at the Crick 
and will have access to excellent state-of-the-art facilities but will work in 
close collaboration with the Thurston group and a newly appointed postdoc at 
Imperial College who will study the cellular functions of SteE and its effects 
on the host metabolome.
Details and application link can be found here:
https://www.crick.ac.uk/careers-study/vacancies/2021-05-20-postdoctoral-training-fellow

If you have any questions, please don't hesitate to contact me.
Katrin

-
Katrin Rittinger, PhD
The Francis Crick Institute
Molecular Structure of Cell Signalling Laboratory
1 Midland Road
London NW1 1AT, UK

Tel: ++44 (0)20 37962274
katrin.rittin...@crick.ac.uk


The Francis Crick Institute Limited is a registered charity in England and 
Wales no. 1140062 and a company registered in England and Wales no. 06885462, 
with its registered office at 1 Midland Road London NW1 1AT



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position at the University of British Columbia, Vancouver.

[Filip Van Petegem]

Dear ccp4bb,


A position is available for a highly motivated and skilled Post-doctoral
Fellow (PDF) at the University of British Columbia in Vancouver, Canada.
The successful candidate will lead cryo-EM experiments to understand
potassium ion channel complex gating and drug regulation in the heart.
The position will be held within the Life Sciences Centre and Departments
of APT and Biochemistry and Molecular Biology at the University of British
Columbia (UBC), under the co-supervision of Dr. David Fedida and Dr. Filip
Van Petegem.



The successful applicant must have a Ph.D. in structural biology. Excellent
theoretical knowledge and practical skills in either X-ray crystallography
or cryo-EM are required. Familiarity with the production and purification
of membrane proteins is a major plus.  The position forms part of a
collaborative, multidisciplinary effort between the Fedida and Van Petegem
laboratories. As such, excellent oral and written English communication
skills, the proven ability to work and as part of a team, and strong
individual research productivity are essential.



Qualified Applicants should submit a cover letter including contact
information for three professional references, and a curriculum vitae
including a list of publications (*n.b.* do not include reprints).
Application materials should be combined into a single PDF document and
submitted via email to david.fed...@ubc.ca and filip.vanpete...@gmail.com



The position is available immediately. The appointment will be at the rank
of Postdoctoral Fellow with a salary commensurate with research experience,
plus benefits (see
https://hr.ubc.ca/benefits/eligibility-enrolment/eligibility-and-plan-cost/faculty-postdoctoral-fellows-employees-and
 ).



*Equity and diversity are essential to academic excellence. An open and
diverse community fosters the inclusion of voices that have been
underrepresented or discouraged. We encourage applications from members of
groups that have been marginalized on any grounds enumerated under the B.C.
Human Rights Code, including sex, sexual orientation, gender identity or
expression, racialization, disability, political belief, religion, marital
or family status, age, and/or status as a First Nation, Metis, Inuit, or
Indigenous person.*






-- 
Filip Van Petegem, PhD
Professor, Dept. of Biochemistry and Molecular Biology
The University of British Columbia
2350 Health Sciences Mall - Rm 2.356
Vancouver, V6T 1Z3

phone: +1 604 827 4267
email: filip.vanpete...@gmail.com
http://crg.ubc.ca/VanPetegem/

Twitter: @FilipPetegem



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position at Imperial College London

[Zhang, Xiaodong]

Dear all

There is a postdoc position available in my lab. For details and how to apply, 
please follow this link.

https://www.imperial.ac.uk/jobs/description/MED02162/research-associate-structural-biology

kind regards

Prof Xiaodong Zhang, Section of Structural Biology, Department of Infectious 
Disease, Imperial College London
Room 104, Sir Alexander Fleming Building, South Kensington, SW7 2AZ
xiaodong.zh...@imperial.ac.uk, (0) 207 
594 3151, http://www.imperial.ac.uk/people/xiaodong.zhang

PA - Ms Kasia Pearce, 
structuralbiolog...@imperial.ac.uk, 
(0) 207 594 2917





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc position in structural biology

[Shaun Olsen]

Dear Colleagues,

A postdoctoral position is immediately available for a highly motivated 
individual interested in understanding molecular mechanisms of ubiquitin 
signaling.  Research is focused on the enzymatic machinery responsible for 
protein ubiquitination, characterization of PROTAC complexes with potential 
therapeutic value, and structure determination of large protein complexes 
involved in ubiquitin signaling, particularly those regulating DNA repair.  
These issues will be addressed using a multidisciplinary approach that includes 
cryo-EM, X-ray crystallography, and NMR complemented with 
biochemical/biophysical techniques and cell-based assays.  

Candidates should hold a recently obtained PhD in biochemistry, chemistry, or 
related subject, with demonstrated expertise in cryo-EM, X-ray crystallography, 
and/or the biochemical analysis of protein ubiquitination.  Experience with 
protein expression in insect and mammalian cells is a plus.

Interested candidates should e-mail a cover letter, CV, and the names of three 
references to: ols...@uthscsa.edu.

Shaun K. Olsen
Associate Professor
Department of Biochemistry & Structural Biology
University of Texas Health Science Center at San Antonio
7703 Floyd Curl Drive, BSB413C/414C
San Antonio, TX 78229
Phone: 210-450-3091
E-mail: ols...@uthscsa.edu



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Position in Structural Biology at UC San Diego

Postdoc Position in Structural and Functional Characterization of 
Macromolecular Complexes in Transcription and Repair

A postdoc position, supported by NIH funding, is available in the Dong 
Wang Lab at University of California, San Diego. 

Our research focuses on the interplay between two fundamental 
processes: transcription and DNA repair. Current research projects focus on the 
X-ray and CryoEM structural elucidation and functional/biochemical study of 
macromolecular protein-nucleic acid complexes involved in transcription, 
chromatin remodeling, and DNA repair. Please visit https://dongwang.ucsd.edu 
for details of our recent research and publications.

We are looking for a highly motivated individual with experiences in 
biochemistry, and molecular biology, X-ray crystallography, or CryoEM. We 
sincerely invite you join our small, but vibrant and highly productive team. 
Candidates must have at least one original first author publication in the 
related field in an internationally recognized journal. Please send your CV, 
list of publications, and the names and Email addresses of 2-3 references to 
dongw...@ucsd.edu before Oct 15, 2021.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc position micro electron diffraction / single particle analysis @Braunschweig/Germany

[Blankenfeldt, Wulf]

Dear colleagues,

together with Rolf Müller (one of this year's Leibniz Prize winners in Germany) 
we are currently looking for a postdoc to help us establish micro electron 
diffraction (and single particle analysis) in natural product research. Details 
about the position can be found here:

https://www.helmholtz-hzi.de/en/career/open-positions/jobs/view/job/details/research-associate-postdoc-fmd/

I'd be grateful if you could inform potential candidates.

Regards,


Wulf




Helmholtz-Zentrum für Infektionsforschung GmbH | Inhoffenstraße 7 | 38124 
Braunschweig | www.helmholtz-hzi.de

Vorsitzende des Aufsichtsrates: Frau MinDir'in Prof. Dr. Veronika von Messling
Stellvertreter: MinDirig Rüdiger Eichel, Niedersächsisches Ministerium für 
Wissenschaft und Kultur
Geschäftsführung: Prof. Dr. Dirk Heinz; Silke Tannapfel
Gesellschaft mit beschränkter Haftung (GmbH)
Sitz der Gesellschaft: Braunschweig
Handelsregister: Amtsgericht Braunschweig, HRB 477



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/