[NMusers] Next Impact Webinar on Analysis of Big Data with Dr. Ghosh at The Systems Biology Institute

Garuda: Fly to the future of biology by Samik Ghosh, Ph.D. Senior Scientist The Systems Biology Institute Tokyo, Japan March 11, 2015 12:00 to 1:00 pm EST Abstract: With the ever-increasing diversity of omics-scale experimental data, a key challenge is the ability to discover the

[NMusers] Next Rosa Impact Webinar Announcement

, an archive of past webinars, and a list of future webinar speakers may be found at www.rosaandco.com/webinar.htmlhttp://www.rosaandco.com/webinar.html Rebecca Baillie Rebecca Baillie Chief of Staff Rosa Co, LLC rbail...@rosaandco.com

[NMusers] Next Impact Webinar by Peter Bonate, Astellas

Modeler. Tailor. Listener. Buy Peter L. Bonate, PhD, Senior Director, Astellas Global Head - Pharmacokinetics, Modeling, and Simulation Global Clinical Pharmacology Exploratory Development July 15, 2015 1:00 - 2:00 pm EDT Presenting modeling and simulation results to an audience can be a

[NMusers] Next Impact Webinar by Satyaprakash Nayak, Pfizer

Development of a Quantitative Systems Pharmacology Model of the Blood Coagulation Network & its Application to Clinical Programs by Satyaprakash Nayak, Pharmacometrician, Systems Biologist at Pfizer September 16, 2015, 1:00 to 2:00 pm EDT Abstract: A number of therapeutics have been developed or

[NMusers] Director level job opening

Principal, PhysioPD™ Rosa & Co. LLC is the world-wide commercial leader in quantitative systems pharmacology. Rosa supports clients with their critical decisions – from preclinical through clinical development – with the creation and use of mathematical PhysioPD Research Platforms. These

[NMusers] Upcoming QSP Webinar

AbbVie Dermatology QSP Platform: Build Strategy and Applications in Psoriasis Drug Discovery and Clinical Development by Oliver Ghobrial, Sr. Scientist III Systems Pharmacology/DMPK/PKPD, AbbVie, Inc. April 13, 2016 12:00 - 1:00 pm EDT Abstract: In immune disease, complex interactions between

[NMusers] Webinar: Mathematical Optimization of Combination Therapy Regimens

Mathematical Optimization of Combination Therapy Regimens by Helen Moore, Ph.D., Associate Director Quantitative Clinical Pharmacology Bristol-Myers Squibb; Princeton, NJ September 14, 2016 12:00 to 1:00 pm EDT Register at http://rosaandco.com/webinarMoore.html Abstract: Combination therapy

[NMusers] Webinar: Applying QSAR and PBPK Modeling to Bridge Discovery and Assessment of Clinical Potential

Webinar: Applying QSAR and PBPK Modeling to Bridge Discovery and Assessment of Clinical Potential Michael Bolger, Ph.D. and Ted Grasela, Ph.D. Oct 19, 2016, 12:00 to 1:00 EDT Abstract: Mechanistic absorption and physiologically-based pharmacokinetic models play an ever increasing role in

[NMusers] Upcoming QSP webinar

Considerations for Adapting Published Models for PhysioPD-Style Research Michael Weis, PhD Senior Engineer, PhysioPD™ Rosa & Co LLC, San Carlos, CA March 22, 2017, 12:00 pm to 1:00 pm EDT Registration: http://www.rosaandco.com/webinars/2017/weis Abstract: The utilization of published models

[NMusers] Upcoming PK-PD Webinar

A PK-PD Modeling and Simulation Based Strategy for Clinical Translation of Antibody-Drug Conjugates: A case study with T-DM1 Aman Singh, PhD PhD Candidate Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY April 19, 2017, 12:00 pm to 1:00 pm EDT Register at

[NMusers] Upcoming QSP webinar with Valeriu Damian, GSK

QSP - What’s in it for me? Case study examples July 19, 2017 12:00-1:00 PM EDT Register at http://www.rosaandco.com/webinars/2017/damian Valeriu Damian, Director Systems Modeling and Translational Biology GlaxoSmithKline, King of Prussia, PA Drug discovery efforts, often based on qualitative

[NMusers] Approaches to Reproducibility in Systems and Physiological Modeling

Upcoming webinar: Approaches to Reproducibility in Systems and Physiological Modeling By Herbert Sauro, PhD Associate Professor, Department of Bioengineering, University of Washington, Seattle, WA June 14, 2017, 12:00 pm to 1:00 pm EDT Register at

[NMusers] Upcoming modeling webinar

Development of a multiscale skin barrier model for de novo, in silico prediction Dr. Ryan Tasseff, Scientist, Procter and Gamble September 13, 2017 12:00-1:00 PM EDT Register for free: https://register.gotowebinar.com/register/722139264316130 We developed a multiscale, many-cell skin barrier

[NMusers] Webinar: Quantitative Modeling in Support of the Development of a Lupus Drug

Quantitative Modeling in Support of the Development of a Systemic Lupus Erythematosus Drug Konstantinos (Kostas) Biliouris, PhD Principal Pharmacometrics Scientist, Novartis, Cambridge, MA, USA Wednesday, Dec 13, 2017, 12:00 pm to 1:00 pm EST Register at

[NMusers] Webinar: QSP modelling - At the heart of the action

QSP modelling - At the heart of the action Speaker: Nelleke Snelder, Senior Consultant, LAP Consultants, Leiden, The Netherlands Thursday, Nov 16, 2017, 12:00 pm to 1:00 pm EDT Register at https://register.gotowebinar.com/register/3899274333265939713 Abstract: PKPD modelling has developed

[NMusers] Webinar: Ten Simple Rules of Credible Practice of Modeling and Simulation in Healthcare:

Webinar: Ten Simple Rules of Credible Practice of Modeling and Simulation in Healthcare: Application to Bone Remodeling and Heart Valve Modeling Lealem Mulugeta and Andrew Drach Executive Committee Members of the Committee for the Credible Practice of Modeling & Simulation in Healthcare

[NMusers] Webinar: Automated scale reduction of nonlinear QSP models with an example of a bone biology system

Webinar: Automated scale reduction of nonlinear QSP models with an example of a bone biology system Chihiro Hasegawa, PhD PK/PD Scientist, Ono Pharma, Japan, Otago Pharmacometrics Group, University of Otago, New Zealand Wednesday Jan 24, 2018, 4:00 pm to 5:00 pm EST Notice: different time

[NMusers] Webinar AI and drug development

Advancing Drug Development and Outcomes Research with Artificial Intelligence, Machine Learning, and Predictive Models Richard Gliklich, MD Founder and CEO, OM1 Wed, July 18, 2018, 1:00 pm to 2:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: The convergence of

[NMusers] Webinar by Richard Gray, FDA

The Potential Impact of Physiological Computer Models in Medicine: Regulation and Considerations for Ensuring Patient Safety Richard A. Gray, PhD, Senior Research Biomedical Engineer Food and Drug Administration (FDA) Wednesday, Mar 14, 2018, 12:00 pm to 1:00 pm EST Register at

[NMusers] Webinar: Ensuring your QSP model is useful

How to Ensure Your QSP Model is Useful - Illustrative Examples and Lessons Learned Christina Friedrich, PhD and Mike Reed, PhD Chief Engineer and Chief Scientist, Rosa & Co. Wednesday, April 25, 2018, 12:00 pm to 1:00 pm EST Register at https://www.rosaandco.com/webinars Abstract:

[NMusers] Upcoming webinar on how to use gPKPDSim

In Rosa's next monthly webinar on Oct 24th at 1:pm EDT, Iraj Hosseini, the scientist at Genentech who was one of the main drivers behind gPKPDSim, a SimBiology-based GUI for PKPD modeling in drug development, will demonstrate his app and show others how they can use it in their research.

[NMusers] QSP/oncology webinar

Enhancing Phase I Clinical Decision Making Through QSP Modeling: A Case Study of Mosunetuzumab in Relapsed/Refractory Non-Hodgkin's Lymphoma Chi-Chung Li, Ph.D., Senior Scientist, and Iraq Hosseini, Ph.D., Scientist at Genentech Wednesday, Jan 23, 2019, 12:00 to 1:00 pm EST Register at

[NMusers] Webinar by Eric Sobie: QSP, Machine Learning, Cardiotoxicity

Combining mechanistic modeling with machine learning to predict cardiotoxicity and streamline drug development Eric Sobie, PhD Professor, Pharmacological Sciences Icahn School of Medicine at Mount Sinai, New York, NY Wednesday, December 12, 2018, 12:00 to 1:00 pm EST Register at

[NMusers] Webinar: System Level Modeling of the Human Gut Microbiome

System Level Modeling of the Human Gut Microbiome Prasad Dhurjati, PhD Professor of Chemical & Bio-molecular Engineering, Joint appointment as Professor Biological Sciences and Professor of Mathematical Sciences, University of Delaware Thursday, September 20, 2018, 12:00 pm to 1:00 pm EDT

[NMusers] Pharmacometrics Webinar with Stephan Schmidt, March 14th

Pharmacometrics, PBPK, QSP - What's Next? Stephan Schmidt, B.Pharm, Ph.D., F.C.P. Center for Pharmacometrics & Systems Pharmacology, University of Florida  Thursday, March 14, 2019, 12:00 to 1:00 pm EDT Register at https://www.rosaandco.com/webinars Abstract:  Modeling & simulation (M) tools

[NMusers] Webinar: Dynamic Models for Personalized QSP: How models can help us explore big data

Dynamic Models for Personalized QSP: How models can help us explore big data Professor Ioannis (Yannis) P. Androulakis , Biomedical Engineering, Rutgers University Tuesday, Feb 12, 2019, 12:00 to 1:00 pm EST Register at https://www.rosaandco.com/webinars Abstract: In this presentation

[NMusers] Webinar with Dr. Bansal, GSK on QSP Models

Webinar: Modular development and application of platform QSP models to support a broad R portfolio: Examples from immuno-oncology and respiratory therapeutic areas Loveleena Bansal, PhD Scientific Leader, GSK Associate Fellow, at GSK, Collegeville PA Jun 20, 2019 12:00-1:00 PM EDT Registration

[NMusers] Upcoming webinar: Expanding from Basic Towards Systems Pharmacodynamic Models for Methylprednisolone

Expanding from Basic Towards Systems Pharmacodynamic Models for Methylprednisolone Vivaswath S. Ayyar, Ph.D., Research Assistant Professor of Pharmaceutical Sciences, University at Buffalo, NY and PK/PD Scientist, Janssen BioTherapeutics, Spring House, PA Thursday May 23, 2019, 12:00 to 1:00

[NMusers] Webinar with Dr. Trujillo, Merck on QSP Model for Proinsulin to Insulin Conversion Therapy

Leveraging a Diabetes QSP Model to Drive Decisions in Target Identification and Validation for Proinsulin to Insulin Conversion Therapy Maria Trujillo PhD Principal Scientist, Merck and Co Inc, Kenilworth, NJ July 18, 2019 12:00-1:00 PM EDT Registration (Free) at

[NMusers] Webinar: Attack of the Clones: Understanding the kinetics of resistance to cancer treatment

Attack of the Clones: Understanding the kinetics of resistance to cancer treatment James Yates, MMath, PhD, Principal Scientist, AstraZeneca, Cambridge UK Wednesday Sep 18, 2019, 12:00 to 1:00 pm EDT Register for free at https://register.gotowebinar.com/register/4098877494283132684 Abstract:

[NMusers] Seeking Biological Systems Modelers

Position Announcement Biological Systems Modeler Rosa & Co. LLC is seeking a Modeling Engineer to join our PhysioPD(tm) consulting practice. Rosa is a drug-disease modeling and simulation company created to provide innovative modeling solutions to its pharmaceutical clients and meaningful

[NMusers] Open positions for Scientists

Position announcement Associate Life Scientist and Senior Life Scientist, PhysioPD Rosa & Co. LLC is seeking Associate and Senior Life Scientists to join our PhysioPD(tm) consulting practice. Rosa is a drug-disease modeling and simulation company created to provide innovative modeling solutions

[NMusers] Upcoming Modeling Webinar by Dr. Britta Goebel for World Diabetes Day

Quantitative Systems Pharmacology Modeling Support in Development of Novel Diabetes Treatments Dr. Britta Goebel Head of Translational Disease Modeling (Diabetes-CV & I) at Sanofi, Frankfurt Thursday Nov 14, 2019, 12:00 to 1:00 pm EST (World Diabetes Day) Register for free at

[NMusers] Upcoming webinar: Hybrid Genetic Algorithm Approaches to Model Selection

Hybrid Genetic Algorithm Approaches to Model Selection Speaker: Robert Bies, Pharm.D. Ph.D Associate Professor of Pharmaceutical Sciences, Member Computational and Data Enabled Sciences Program University at Buffalo, NY Thursday, Oct 24, 2019, 12:00 to 1:00 pm EDT Register for free at

[NMusers] 2020 BAPKPD Poster Social

Please join us at the annual Bay Area PKPD 2020 Poster Social on Wednesday, March 25th from 1:00 pm to 5:00 pm at Merck Research Laboratories in South San Francisco. We welcome you to submit your recent posters presented at other meetings for a "second chance" to be displayed for the benefit of

[NMusers] Upcoming webinar: Jeffrey Sachs from Merck on MIDD

MIDD: Vaccine R Gets a Shot in the Arm from Pharmacometrics Jeffrey R. Sachs, PhD Senior Principal Scientist at Merck & Co. Wednesday Jan 22, 2020, 12:00 to 1:00 pm EST Register for free at https://www.rosaandco.com/webinars Abstract: The objective is to (1) inform the audience about

[NMusers] Webinar: gQSPSim: a SimBiology-based GUI app for standardized QSP model development and application

gQSPSim: a SimBiology-based GUI app for standardized QSP model development and application Iraj Hosseini, PhD and Justin Feigelman, PhD Scientists at Genentech, Inc Wednesday, April 15, 2020, 12:00 to 1:00 pm EDT Register for free at

[NMusers] Webinar on Modeling and Policy Change

Of "clever" models and "dumb" spreadsheets": what is more effective to drive policy change? Paolo Denti, PhD, Associate Professor at the University of Cape Town When: Wednesday May 20, 2020, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: What often prevents

[NMusers] Stacey Tannenbaum: Making the 'Moster' of Your Poster Webinar tomorrow

Making the 'Moster' of Your Poster Stacey Tannenbaum, PhD, FISoP Senior Director, Pharmacometrics US Clinical Pharmacology and Exploratory Development, Astellas Pharma, Northbrook, IL September 9, 2020 12:00-1:00 PM EDT Register for free at https://www.rosaandco.com/webinars An excerpt from a

[NMusers] Webinar: Do you need a life scientist for QSP modeling?

Do you need a life scientist for QSP modeling? Katherine Kudrycki, PhD, Principal Scientist at Rosa & Co. LLC On October 14, 2020 at 12:00-1:00 PM EST Register for free at https://www.rosaandco.com/webinars Abstract: While QSP models are defined as comprehensive models of biological mechanisms,

[NMusers] Webinar: QSP model of Schizophrenia

Development of a QSP Platform to Quantify Benefits of DAAO Inhibition in Schizophrenia Sergio Iadevaia, PhD Scientific Director QSP, Pharmacometrics and Data Analysis at Takeda Wednesday June 17, 2020, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract:

[NMusers] Webinar: An Integrated Machine Learning Framework for Novel Small Molecule Drug Design

An Integrated Machine Learning Framework for Novel Small Molecule Drug Design Dr. Jonathan E. Allen, Informatics Thrust Leader, Biosecurity Center at ATOM Consortium Wednesday July 15, 2020, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: The drug discovery

[NMusers] Upcoming webinar by Paul Watkins on QST

QST and the Transformation in Drug Safety Assessment Paul B. Watkins, M.D. FAASLD Director, Institute for Drug Safety Sciences , University of North Carolina in Chapel Hill Wednesday December 16, 2020, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract:

[NMusers] Upcoming webinar: Using QSP to predict cardiotoxicity caused by cancer drugs

Using QSP to predict cardiotoxicity caused by cancer drugs Eric Sobie, PhD Professor, Pharmacological Sciences at Icahn School of Medicine at Mount Sinai November 18, 2020 at 12:00-1:00 PM EST Register for free at https://www.rosaandco.com/webinars Abstract Tyrosine kinase inhibitor drugs, or

[NMusers] Webinar: Using QSP to predict cardiotoxicity caused by cancer drugs

Using QSP to predict cardiotoxicity caused by cancer drugs Eric Sobie, PhD Professor, Pharmacological Sciences at Icahn School of Medicine at Mount Sinai, NY Wednesday November 18, 2020, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: Tyrosine kinase

[NMusers] Webinar on Complex Drug-Protein Interactions

Building Kinetic Models with Complex Drug-Protein Interactions: application to the targeted inhibition of MAPK signaling in cancer Luca Gerosa, PhD, Postdoctoral Fellow, Laboratory of Systems Pharmacology, Harvard Medical School Wednesday January 20, 2021, 12:00 to 1:00 pm EDT Register at

[NMusers] BAPKPD Network Special Topics Webinar: Dr. Giacomini, High Throughput Screening and Real World Biomarkers to Predict Drug-Drug and Drug-Nutrient Interactions: Implications to polypharmacy as

Bay Area PKPD Network Special Topics Webinar Thursday, June 10, 2021 from 12:00pm-1:00pm PDT Location: Online Register: for free at https://tinyurl.com/BAPKPD-webinar2021 or see http://www.bapkpd.org/upevent.html for information Kathy Giacomini, Ph.D. Professor, Department of

[NMusers] Webinar: Dr. Siokis from Sanofi: An agent-based simulation platform studying the immunological synapse dynamics

An agent-based simulation platform studying the immunological synapse dynamics Anastasios Siokis, PhD, Postdoc in Translational Disease Modeling, Sanofi, Germany June 9, 2021 12:00-1:00 PM EDT Registration (Free): https://www.rosaandco.com/webinars Abstract: During immunological synapse (IS)

[NMusers] Webinar: Integrating Quantitative Systems Pharmacology and Machine learning, why bother?

Integrating Quantitative Systems Pharmacology and Machine learning, why bother? Tongli Zhang, PhD, Assistant Professor, University of Cincinnati Wednesday July 14, 2021, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: It is challenging to understand complex

[NMusers] Upcoming webinar: Predicting subjective or complex clinical outcomes in QSP models

Predicting subjective or complex clinical outcomes in QSP models: challenges and approaches Vincent Hurez, DVM, PHD, Senior Scientist, Rosa & Co LLC Wednesday May 12, 2021, 12:00 pm to 1:00 pm EDT Register for free at: https://www.rosaandco.com/webinars Abstract: Many clinical trials use complex

[NMusers] Webinar: Modeling Physician Decision-Making Behavior Using Discrete Choice

Out of the Lab - Into the Market: Modeling Physician Decision-Making Behavior Using Discrete Choice Bill Brastow, PhD Principal and CTO Rosa Market Modeling, Rosa & Co Tuesday February 16, 2021, 12:00 to 1:00 pm EDT Register for this free webinar at https://www.rosaandco.com/webinars Abstract:

[NMusers] Webinar: The Ravaging Respiratory Infection: Fighting Influenza Using Mechanistic Models

The Ravaging Respiratory Infection: Fighting Influenza Using Mechanistic Models Amber M. Smith, PhD Assistant Professor, University of Tennessee Health Science Center Wednesday March 17, 2021, 11:00 am to 12:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: Respiratory

[NMusers] Webinar: Probing antibody-target interactions in living systems

Probing antibody-target interactions in living systems Yanguang (Carter) Cao, PhD., Assistant Professor, University of North Carolina at Chapel Hill September 15, 2021, 9:00-10:00 AM PDT Register for free at https://www.rosaandco.com/webinars Abstract: Antibodies have become an attractive class

[NMusers] Webinar with Dr. Palmer on modeling combination cancer therapy

Models to understand and predict the clinical efficacy of combination cancer therapy Dr. Adam Palmer Assistant Professor of Pharmacology, University of North Carolina at Chapel Hill Wednesday October 20, 2021, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars

[NMusers] Webinar: A mechanistic model-based analysis of Fn14 - NFκB dysregulation in glioblastoma multiforme

A mechanistic model-based analysis of Fn14 - NFκB dysregulation in glioblastoma multiforme Dr. Dipak Barua, Research Principal Scientist at Takeda Wednesday December 8, 2021, 12:00 to 1:00 pm EST Register for free at https://www.rosaandco.com/webinars Abstract: Fn14 is a transmembrane receptor

[NMusers] Webinar: Using Machine Intelligence in Building PK/PD and Disease Progression Models.

James Lu, PhD. Principal AI Scientist, Genentech Using Machine Intelligence in Building PK/PD and Disease Progression Models. Nov 17, 2021, 9:00-10:00 AM PST. Register for free at https://www.rosaandco.com/webinars Abstract: The analyses of time course data from clinical trials are currently

[NMusers] March Webinar: Nick Holford

Concentration Guided Dosing Nick Holford, MB, ChB, MSc, FRACP, Professor Emeritus Clinical Pharmacology, Department of Pharmacology and Clinical Pharmacology, University of Auckland, New Zealand Wednesday March 16, 2022, 12:00 to 1:00 pm EDT Register for free at

[NMusers] Webinar: Using Machine Learning Surrogate Modeling for Faster QSP VP-Cohort Generation

Using Machine Learning Surrogate Modeling for Faster QSP VP-Cohort Generation Christina Friedrich, PhD; Jérémy Huard Chief Engineer, PhysioPD, Rosa & Co, LLC; Senior Application Engineer, MathWorks Wednesday February 16, 2022, 12:00 to 1:00 pm EST Register for free at

[NMusers] Dr. Joga Gobburu presents 'Predictive Healthcare Analytics'

Predictive Healthcare Analytics A webinar by Dr. Joga Gobburu Professor, University of Maryland Wednesday April 20, 2022, 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: We started our journey as clinical pharmacologists with pharmacokinetics (PK),

[NMusers] Sept. Webinar: A Pharmacodynamic Model for the Assessment and Optimization of PROTACs

A Pharmacodynamic Model for the Assessment and Optimization of PROTACs Robin T.U. Haid, MSc, PhD Student, Bayer AG, Preclinical Development, Drug Metabolism and Pharmacokinetics, Preclinical Modeling and Simulation / ETH Zurich, Institute of Pharmaceutical Sciences, Biopharmacy Wednesday,

[NMusers] Nov. Webinar: Understand Tumor Response Heterogeneity in Colorectal Cancer: Share the similarities, celebrate the differences.

Understand Tumor Response Heterogeneity in Colorectal Cancer: Share the similarities, celebrate the differences. Jiawei Zhou, PhD, Pharmacometrician, Pfizer Inc., New York Wednesday, November 15, 2023, 12:00-1:00 PM EST Register at https://rosaandco.com/webinars Abstract: Achieving systemic tumor

[NMusers] Oct. Webinar: PK/PD modelling of eflornithine: Assessment of an oral treatment for the fatal parasitic disease human African trypanosomiasis

Mikael Boberg, PhD, Senior Scientist, AstraZeneca R, Gothenburg, Sweden Wednesday, October 11, 2023, 9:00 to 10:00 am PDT Register (free) at https://rosaandco.com/webinars Abstract: Human African trypanosomiasis, also known as sleeping sickness, is a fatal parasitic disease if not treated. It is

[NMusers] Virtual Patients Webinar Roundtable

VPs... You got to know when to hold them, know when to remove them, know when to resample, know when to run. Date: July 13th (14th in NZ). 8am NZST/ 1pm PST/ 4pm EST Register for free at https://rosaandco.com/webinars Abstract: Typically, the workflow of a QSP model includes the creation,

[NMusers] Webinar: Analyzing Outcome Score Data by Chuanpu Hu, Janssen R

Analyzing Outcome Score Data Chuanpu Hu, PhD Senior Scientific Director and Fellow, Janssen R, LLC Wednesday, May 25, 2022 12:00 to 1:00 pm EDT Register for free at https://www.rosaandco.com/webinars Abstract: Clinical trial endpoints are often bounded outcome scores which take restricted

[NMusers] Webinar: AI-powered modeling approaches to support the development of new therapies for autoimmune diseases

AI-powered modeling approaches to support the development of new therapies for autoimmune diseases Philippe Moingeon, PhD, MBA, Head of Immuno-inflammation Portfolio, Servier Wednesday, September 21, 2022, 9:00 to 10:00 am PDT Register for free at

[NMusers] Webinar by Dr. Krzyzanski, Pharmacodynamic age-structured population model for cell trafficking

Wojciech Krzyzanski PhD, MA Associate Professor, University at Buffalo Pharmacodynamic age structured population model for cell trafficking October 19, 2022, 9:00-10:00 AM PDT Registration (Free):

[NMusers] Webinar: Injecting Reality into The Commercial Due Diligence Process for In-Licensing, Partnering, or Purchasing Pharmaceutical Assets in Development.

Injecting Reality into The Commercial Due Diligence Process for In-Licensing, Partnering, or Purchasing Pharmaceutical Assets in Development. Bill Brastow, Ph.D., CTO, Market Modeling, Rosa & Co LLC, San Carlos, CA Wednesday, August 17, 2022, 9:00 to 10:00 am PDT Register for free at

[NMusers] Vincent Lemaire and Fei Hua webinar: Perception of the Use and Impact of QSP in immuno-oncology

"From Cold to Hot: Perception of the Use and Impact of QSP in immuno-oncology – A Survey of the Community and Stakeholders". Vincent Lemaire, Distinguished Scientist Modeling and Simulation, Genentech, South San Francisco, CA Fei Hua, VP, Head of modeling and simulation services, Applied

[NMusers] Webinar: A case‐study of model‐informed drug development

A case‐study of model‐informed drug development of a novel PCSK9 anti sense oligonucleotide Presented by Dr Dinko Rekic, PhD and Dr Jane Knöchel, PhD Global Product Leader – ticagrelor; Clinical Pharmacometrician, AstraZeneca, Gothenburg, Sweden February 8, 2023, 9:00-10:00 AM PST Register at

[NMusers] Webinar: Variability and uncertainty: interpretation and usage of pharmacometric simulations and intervals

Variability and uncertainty: interpretation and usage of pharmacometric simulations and intervals Chuanpu Hu, PhD. Senior Scientific Director and Fellow, Janssen R, LLC Wednesday, November 16, 2022, 9:00 to 10:00 am PST Register at https://rosaandco.com/webinars Abstract: Pharmacometric modeling

RE: [NMusers] March Modeling Webinar: Pharmacokinetic modeling for antivenom development

This is a great example for the use of PK/PD and should be of interest to anyone developing venom-based drugs or antibody/nanobody drugs. Defining Design Rules for Next-Generation Snakebite Antivenoms Natalie Morris University of Bristol, Bristol, UK Wednesday, March 15th at 9:00 PDT Register

[NMusers] Present an Early Career Investigator Webinar

Reminder to send in an abstract for Rosa’s Early Career Investigator Webinars Rosa is seeking PhD students, postdoctoral scholars, and early researchers in academia & industry to present as part of the Rosa World Wide Webinar series. These webinars will support outstanding early career

[NMusers] Early career investigators wanted to give a webinar

Apply to present in Rosa's Early Career Investigator Webinars Rosa is seeking PhD students, postdoctoral scholars, and early researchers in academia & industry to present as part of the Rosa World Wide Webinar series. These webinars will support outstanding early career investigators by

[NMusers] March Modeling Webinar: Pharmacokinetic modeling for antivenom development

Defining Design Rules for Next-Generation Snakebite Antivenoms Natalie Morris University of Bristol, Bristol, UK Wednesday, March 15th at 9:00 PDT Register for free at https://rosaandco.com/webinars Abstract Snakebite is a neglected tropical disease which causes over 100,000 deaths and 400,000

[NMusers] Webinar: QSP Modeling to Support a New Dose Application

Demonstrating Efficacy When Clinical Trials Are Impossible: QSP Modeling to Support a 505(b)(2) Application Rebecca Baillie, PhD, Christina Friedrich, PhD, Jake Nichols, PharmD, MBA Principal Scientist, Chief Engineer, Rosa & Co. San Carlos, CA; Director of Medical Affairs, US World

[NMusers] Webinar on Wednesday: Modeling IFNα signaling

Mechanistic insights into sensitization/desensitization of IFNα signaling and its effect on patient treatment strategies. Dr. Marcus Rosenblatt, PhD University of Freiburg, Freiburg, Germany July 12, 2023, 12:00-1:00 PM EDT Register for free at

[NMusers] June Webinar: A QSP Model to Understand Clinical Cytokine Dynamics Following Bispecific Dosing in Solid Tumors

June Webinar: A QSP Model to Understand Clinical Cytokine Dynamics Following Bispecific Dosing in Solid Tumors Jared Weddell, PhD, Senior Manager, Clinical Pharmacology and Exploratory Development Astellas Pharma US, Northbrook, IL Wednesday, June 14, 2023, 9:00 to 10:00 am PDT Register for

[NMusers] August Webinar: Proteomics-Informed PBPK Modeling to Predict Systemic and Tissue Drug Concentrations in Rats

Proteomics-Informed PBPK Modeling to Predict Systemic and Tissue Drug Concentrations in Rats Sheena Sharma, PhD, Research Investigator, PBPK, Clinical Pharmacology, & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ Wednesday, August 16, 2023, 9:00 to 10:00 am PDT Register for free at

[NMusers] Webinar: Proteomics-Informed PBPK Modeling to Predict Systemic and Tissue Drug Concentrations in Rats

Proteomics-Informed PBPK Modeling to Predict Systemic and Tissue Drug Concentrations in Rats Sheena Sharma, PhD, Research Investigator, PBPK, Clinical Pharmacology, & Pharmacometrics, Bristol Myers Squibb, Lawrenceville, NJ Wednesday, August 16, 2023, 9:00 to 10:00 am PDT Register for free at

[NMusers] July Webinar: Modeling IFNα signaling and optimizing treatment strategies

Mechanistic insights into sensitization/desensitization of IFNα signaling and its effect on patient treatment strategies. Dr. Marcus Rosenblatt, PhD University of Freiburg, Freiburg, Germany July 12, 2023, 12:00-1:00 PM EDT Register for free at

[NMusers] May Webinar: Leveraging machine learning strategies for nonlinear mixed effects model selection

Leveraging machine learning strategies for nonlinear mixed effects model selection (using pyDarwin) By Robert R. Bies, Pharm.D. Ph.D. FISoP Professor of Pharmaceutical Sciences, Member Institute for Artificial Intelligence and Data Science. University at Buffalo, Buffalo NY Wednesday, May 17,

[NMusers] February Modeling Webinar: The Long Road from Discovery to Design

The Long Road from Discovery to Design Brian Topp, Senior Director, Merck, Rahway, NJ Feb 21, 2024 12:00-1:00 PM EST Registration is free: https://rosaandco.com/webinars Abstract: Lockheed Martin does not discovery fighter jets. Ferrari dose not discover F1 race cars. Increasingly, the

[NMusers] January webinar: Clinical Trials For Patients Who Are Not Average

Clinical Trials For Patients Who Are Not Average By Tom Yankeelov, Ph.D. W.A. "Tex" Moncrief Chair of Computational Oncology; Director, Center for Computational Oncology, Oden Institute for Computational Engineering and Sciences; Director, Cancer Imaging Research, Livestrong Cancer Institutes;

[NMusers] Dec. Webinar: The Q-ATN Model of Alzheimer’s Disease: A Work in Progress

The Q-ATN Model of Alzheimer’s Disease: A Work in Progress Norman A. Mazer, M.D., Ph.D., Founder and Disease Modeling Consultant, NAM Consulting, Basel, Switzerland Wednesday, December 13, 2023, 12:00-1:00 PM EST Register at https://rosaandco.com/webinars Abstract: The Q-ATN model is a

[NMusers] March Webinar: From data driven to theoretical: improving preclinical decision making with modeling

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