Hi Ravi,

I had lots of problems as well with TPP under Mac OS X 10.6.4 and I
wrote some guidelines to ease the process for others.

Here is the link:
http://tools.proteomecenter.org/wiki/index.php?title=TPP:Installing_the_Trans-Proteomic_Pipeline_%28TPP%29_4.4.0_on_Mac_OS_X_10.6.4

I hope this helps. If not, let us know!

Kind regards,

Bjorn

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