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Hi List-
  I would like to respond to Cynthia's post and her request that breeders address the 
issue. This post is not ment to be argumentative or sarcastic, but a view from another 
side...

Cynthia wrote:
 One thing I think we all need to keep in mind is that yes this occurs in over 30% of 
Cavaliers.  But it has been proven to be
a congenital and hereditary problem.  I hope owners and breeders alike are taking this 
seriously.

First off, my personal experience with thrombocytopenia is nonexistent (in dogs, that 
is!).  I was "alerted" to this issue by my local "generalist" vet who, when I was in 
doing going-home-healthy-puppy checks mentioned that she was treating a 3 1/2 year old 
Cavalier bitch (no relation to mine) for this problem, and was having no luck with the 
normal modes of treatment.  She asked if I knew anything breed specific about it.  I 
recalled that there was discussion about it on the list and told her I would look it 
up. I faxed the information and papers I collected to her (alas, now in a file in 
Hawaii and I'm in chilly 'ole Los Angeles this evening), but my
recollection of the studies etc. was that Cavaliers tend to display thrombocytopenia 
more often, but further investigation showed that they don't actually have the 
syndrome-just that machines used to test  their blood cannot read the larger than 
normal cells.  A manual count often results in normal numbers, though the cells are 
not a common size for most canines...now I may have skimmed too shallow on this issue 
and missed that Cavaliers really DO have a greater incidence of true thrombocytopenia, 
but I came away from my research believing that the problem was with the machines, not 
the dogs.

Cynthia went on to say:
The only way we can combat it is to not breed the Cavaliers if they or their offspring 
is to come up with this.  I think if we don't start taking this seriously in ten years 
it's going to be almost as bad a problem as the mitral valve in instances.  I have had 
responses that basically said (and I'm not repeating or quoting but you will get the 
gist) well it's common in Cavaliers, nothing is wrong and basically why stop breeding 
the animals that it shows up in.

Hummm...one of my favorite sayings is, "if it ain't broke, don't fix it".  In this 
case, if my belief is correct and the issue is of different sized cells, not missing 
cells, then why do we need to address this as breeders?  Unless the larger cells are 
causing a physiological problem, who cares?
  The slippery slope of over-testing is easy to build momentum on-it seems like such 
an easy way out of decision making. We test for heart murmurs, patella's, hips, eyes. 
thyroid, elbows, blood discrepancies.  Got the clearances? Breed it!  Missed on one? 
De-sex it and cry me a river!  Often it is the novice breeders or ones with a lack of 
confidence that bang the clearance drum the loudest.  The truly difficult decision; 
does this animal have unique qualities that we want reproduced, takes a back seat to 
the health clearance scramble.
  Now don't misread me.  There are severe health issues in every breed that can and 
are avoided/decreased by judicious testing and removing affected animal from the 
breeding stock.  But, just because they've come up with a new test doesn't mean we all 
have to rush off to the specialist to clear FiFi. Case in point; in the early 70's, 
the newly formed CERF was deciding what conditions were passable or not.  One of the 
conditions in question was juvenile cataracts, seen most often in Golden Retrievers.  
Juvenile cataracts-sounds scary enough...visions of stumbling pups, blind adolescents. 
 But a juvenile cataract, seen ages 4-6 months and up, is a triangular
shaped opacity on the retina of the eye, very small, stable in size. Dogs with this 
condition rarely have vision impairment.   The CERF asked the National Club which side 
of the list they wanted it on-pass or fail (this is how controversial the impairment 
was-they asked the club!) In the end, it got put down as a CERF fail. To be reviewed 
several years down the line...never was, and the breed has seen untold numbers of 
quality specimens tanked simply because of that non intrusive little " mercedes benz 
sign" on a retina.  Please, don't fix what ain't broke.

She goes on to suggest:
 To me that is the wrong mentality.  I am very into the health & welfare of my animals 
and I care about the breed.  We have enough health problems, why would people want to 
add to them?... This is still a small enough problem that if we work hard we can 
combat it
before it gets out of hand.

Were it easy to combat health problems by selective breeding!  If it was that simple, 
we breeders would no longer be plagued with early onset murmurs, PRA, hip dysplasia 
(now in it's 40th year of selective breeding practices), thyroid deficiencies, and 
that pesky uneven black mark trickling down one hock. Genetics are tricky, and most 
dog breeders are school teachers, nurses, AT&T operators, real estate agents, shop 
keepers...not geneticists.  But it is expected of these breeders, by the purebred dog 
buying public and their vets, that they have the knowledge, wisdom and skill to 
produce happy, healthy and condition free dogs. With guarantees. At a reasonable
cost. With 150% of your money back (to the vet) if the dog has a glitch.( Puppy  lemon 
laws ).  And we breeders are to obtain these skills, this knowledge, that wisdom by 
breeding no more than two litters a year, 'cause everyone knows that you are a puppy 
mill if you do more than that!  No one on this list wants to "add to" the health 
issues in our breed. We dread that phone call from a distraught owner (or worst, clue 
less vet) claiming that the woes of their world is our fault. We cherish and strive 
for those yearly holiday cards that say "Thanks for our wonderful, healthy family 
member, pict. enclosed" .  In the breeding of mammals, simple Mendelian pea nor
fruit fly genetics apply, and we can neither wish nor "breed away" a polygenetic trait 
anymore than we can wish away the actions of the pond scum who indiscriminately bred, 
then discarded Mandy, the Black and Tan rescue in North Carolina.

In our stressful and too short lives we need to "pick our battles", and I'm not yet 
convinced that this is one worth fighting. If  I find that this is truly a condition 
that affects a number of our breed, is detrimental and can be "bred for" (or against, 
as the case may be) then I will as a breeder apply that knowledge to my breeding 
practices. But please don't ask me to fix what ain't broke.
Kim Johnson
Allegria Cavaliers and Gold-Rush Golden Retrievers

P.S.- I STILL want to know why a blood test was run on a healthy young dog visit.  
Geez-we don't run blood panels with human healthy baby, children or adolescent visits 
(though if the insurance would pay for it, we probably would).  I believe that the 
first time most US citizens get their blood drawn is during their Military Service 
exam...the males, that is!

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