Dear Kim and List:

First of all Kim; your post was very well laid out and thought provoking.
I've been slow to respond to most posts, but can't resist this one :)

You mentioned that one of your favourite sayings was "if it ain't broke -
don't fix it".  For me, this is an irksome saying because I honestly
believe that, in most cases, the sayer doesn't even realize that "it" is
broke (or about to break).

You also mentioned that you have not had personal experience with this
disorder (in dogs, that is).  I would wager that your view would be quite
different if this disorder were to blind side you as it has many of us who
have experienced it.  I lost a 6 3/4 year old b/t and her 5 unborn puppies
to this disorder and am not over it yet.

Repeatedly, it is cited that over 30% (31%) of Cavaliers are affected with
this order (this refers to the Swedish study that was published in 1994).
I feel it is important we all realize that this study only included 102
dogs in a small geographical area.  Seven years have passed since that
small study was done and this disorder has never really been studied, save
for the Canadian study of only 11 cases - published in 1997.  We really
have no idea if this 31% is a reasonable indication of the general
population.  It could easily be more serious than that!  Conducting a
survey/testings would qualify that figure.  I had understood that a study
was to be undertaken by the CKCSC-USA Club.  Did that study ever get off
the ground?

In the AVAR's list of congenital/inheritable defects of various breeds;
Cavaliers are listed with 13 noteable disorders.  There are two I consider
to be life "threatening".  MVD is the first and Thrombocytopenia is second.
 While I do realize that Thrombocytopenia affected animals can be
assymptomatic, the question one should ask one's self is "for how long".
This disorder can change to something more serious due to a variety of
possible stresses to the system.  Thrombocytopenia can also be either a
primary or a secondary condition, easily compounded to include IMHA
(immune-mediated hemolytic anemis), or DIC (disseminated intravascular
coagulation) to name a few.  Lethargy, black stools or petechial spots on
gums, groin or eyes are symptoms.  Before one can really address how to
treat this disorder, they must first get a clear understanding of it - and
that "they" don't have yet.  So, from my personal experience, and opinion,
I fully support the concerns that Cynthia expressed.  I would also add here
that I concur with others in that I would not treat assymptomatic dogs and
I am even hesitant to "treat" symptomatic ones either because we don't know
what the base problem is.  For my girl, blood transfusions proved
devastating because her autoimmune system reacted violently (twice) to the
introduction of blood (a foreign protein).

I think that Cavalier owners, be they breeders or pet owners, are
wonderfully open to talking about the issues that face our breed.  Those
that risk sharing their health findings do the breed a great service.  One
or two incidences of a particular problem are not considered a worry to the
breed in general; but several people have posted their personal experiences
with this disorder within this small forum.  IMO, this should be considered
a "heads up - wake up call" and address it, face on, the way I know we are
all capable of doing.  Again IMO, assuming that the study figure of 31%
affected is correct, and saying this condition doesn't warrant the relative
health checks, cannot be a good attitude for the future of our breed.

BTW, I understand that Thyroid testing at the right time, can also provide
valuable information about screening for candidates who may develop
Thrombocytopenia.


Pat Barrington - Barrington Cavaliers (Southern Ontario-Canada)
[EMAIL PROTECTED]

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