F1 ATPase. Got some Nobel glamour too. Sent from tiny silly touch screen
----- Reply message ----- From: "Aaron Thompson" <aaron.a.thomp...@gmail.com> Date: Tue, Jan 28, 2014 01:10 Subject: [ccp4bb] Examples of multiple ASU copies with different conformations To: <CCP4BB@JISCMAIL.AC.UK> The structure of kappa opioid receptor fused with T4 lysozyme (4DJH) contains two copies in the ASU – each copy displays a different orientation between the receptor and lysozyme. On Mon, Jan 27, 2014 at 10:08 AM, Shane Caldwell <shane.caldwel...@gmail.com > wrote: > Hi ccp4bb, > > I'm putting together a talk for some peers that highlights strengths and > weaknesses of structural models for the outsider. For one point, I'd like > to find some examples of proteins that show very different conformations > between different copies in the ASU. One example I know of is c-Abl (1OPL), > which crystallizes with both autoinhibited and active forms in the ASU, > with dramatically different domain organization. I'd like to find some > additional examples - can anyone suggest some other structures that have > multiple copies with large structural variations? > > Thanks in advance! > > Shane Caldwell > McGill University > > >
