In the case of F1-ATPase they are not biologically independent copies in the a.u. though, rather subunits of a biological complex... (but perhaps I interpreted the question to narrowly)
Mark J van Raaij Lab 20B Dpto de Estructura de Macromoleculas Centro Nacional de Biotecnologia - CSIC c/Darwin 3 E-28049 Madrid, Spain tel. (+34) 91 585 4616 http://www.cnb.csic.es/~mjvanraaij On 28 Jan 2014, at 05:38, Frank von Delft wrote: > F1 ATPase. Got some Nobel glamour too. > > Sent from tiny silly touch screen > > ----- Reply message ----- > From: "Aaron Thompson" <aaron.a.thomp...@gmail.com> > Date: Tue, Jan 28, 2014 01:10 > Subject: [ccp4bb] Examples of multiple ASU copies with different conformations > To: <CCP4BB@JISCMAIL.AC.UK> > > The structure of kappa opioid receptor fused with T4 lysozyme (4DJH) > contains two copies in the ASU – each copy displays a different orientation > between the receptor and lysozyme. > > > On Mon, Jan 27, 2014 at 10:08 AM, Shane Caldwell <shane.caldwel...@gmail.com > > wrote: > > > Hi ccp4bb, > > > > I'm putting together a talk for some peers that highlights strengths and > > weaknesses of structural models for the outsider. For one point, I'd like > > to find some examples of proteins that show very different conformations > > between different copies in the ASU. One example I know of is c-Abl (1OPL), > > which crystallizes with both autoinhibited and active forms in the ASU, > > with dramatically different domain organization. I'd like to find some > > additional examples - can anyone suggest some other structures that have > > multiple copies with large structural variations? > > > > Thanks in advance! > > > > Shane Caldwell > > McGill University > > > > > > > >
