On 27 Jan 2014, at 19:08, Shane Caldwell <shane.caldwel...@gmail.com> wrote:
Here is another interesting one: Perez, C., Koshy, C., Yildiz, Ö., & Ziegler, C. (2012). Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP. Nature. best wishes, Tobias > Hi ccp4bb, > > I'm putting together a talk for some peers that highlights strengths and > weaknesses of structural models for the outsider. For one point, I'd like to > find some examples of proteins that show very different conformations between > different copies in the ASU. One example I know of is c-Abl (1OPL), which > crystallizes with both autoinhibited and active forms in the ASU, with > dramatically different domain organization. I'd like to find some additional > examples - can anyone suggest some other structures that have multiple copies > with large structural variations? > > Thanks in advance! > > Shane Caldwell > McGill University > >
